Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: Decitabine (DAC) w/ or w/o Valproic Acid (VPA) in Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML) [Phase 2]
Phase 2 trial update of decitabine with or without valproic acid in myelodysplastic syndrome and acute myelogenous leukemia; completed with …
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CLINICAL_TRIALS trial_result · 2015-08-11Clinical Trial Update: Safety, Tolerability, Pharmacokinetics and Efficacy of AZD1208 in Acute Myelogenous Leukemia (AML) Patients [Phase 1]
Phase 1 clinical trial of AZD1208 in Acute Myeloid Leukemia assessed safety, tolerability, pharmacokinetics and preliminary efficacy; the st…
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CLINICAL_TRIALS trial_result · 2015-08-05Clinical Trial Update: Selumetinib in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update evaluating selumetinib in adults with recurrent or refractory acute myeloid leukemia, including AML with t(15;…
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CLINICAL_TRIALS trial_result · 2015-07-28Clinical Trial Update: Phase 1 Study of CC-486 in Japanese Subjects With Hematological Neoplasms [Phase 1]
Termination of a Phase 1 trial evaluating oral azacitidine (CC-486) in Japanese subjects with hematological neoplasms.
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CLINICAL_TRIALS trial_result · 2015-07-27Clinical Trial Update: Combination of GTI-2040 and Cytarabine in the Treatment of Refractory and Relapsed Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 trial evaluating the combination of GTI-2040 and cytarabine in patients with refractory or relapsed acute myeloid leukemia. The stud…
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CLINICAL_TRIALS trial_result · 2015-07-23Clinical Trial Update: Lipid Use, Nutrition, and Colitis in Patients With Hematological Malignancies [Phase 2]
Phase 2 clinical trial assessing lipid use and nutrition for colitis and mucositis in patients with hematologic malignancies, including AML;…
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CLINICAL_TRIALS trial_result · 2015-07-23Clinical Trial Update: Tipifarnib, Cytarabine, and Daunorubicin in Treating Older Patients With Acute Myeloid Leukemia [Phase 1]
This Phase 1 trial studied a combination of tipifarnib, cytarabine, and daunorubicin in older patients with acute myeloid leukemia; the stud…
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: Efficacy and Safety Study of StemEx®, to Treat Subjects With High Risk Hematologic Malignancies, Following Myeloablative Therapy [Phase 2, Phase 3]
This update summarizes a Phase 2/Phase 3 study of StemEx for high-risk hematologic malignancies after myeloablative therapy, focusing on eff…
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 trial results comparing three combination chemotherapy regimens in adults with relapsed or refractory acute myeloid leukemia; the st…
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CLINICAL_TRIALS trial_result · 2015-07-03Clinical Trial Update: Donor Natural Killer Cells and Aldesleukin in Treating Patients w/High Risk AML Undergoing Donor Stem Cell Transplant [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating donor natural killer cells plus aldesleukin in high-risk acute myeloid leukemia patients undergoing dono…
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: Vorinostat in Combination With Azacitidine in Patients With Newly-Diagnosed Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial evaluating vorinostat in combination with azacitidine in newly diagnosed AML or MDS; study completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2015-07-01Clinical Trial Update: A Phase I/II Study of MGCD0103 With Azacitidine in Patients With High-Risk Myelodysplastic Syndrome (MDS) or Acute Myelogenous Leukemia [Phase 1, Phase 2]
A Phase I/II study evaluating the combination of MGCD0103 with azacitidine in high-risk myelodysplastic syndrome or acute myeloid leukemia h…
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CLINICAL_TRIALS trial_result · 2015-07-01Clinical Trial Update: MGCD0103 in Elderly Patients With Previously Untreated AML/High Risk MDS or Adults With Relapsed/Refractory Disease [Phase 2]
Phase 2 trial of MGCD0103 (mocetinostat) in elderly patients with previously untreated acute myeloid leukemia/high-risk myelodysplastic synd…
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CLINICAL_TRIALS trial_result · 2015-06-26Clinical Trial Update: Study of Infusion of Blood Cells (Lymphocytes) to Stimulate the Immune System to Fight Leukemia/Lymphoma [Phase 2]
A Phase 2 trial evaluating infusion of blood cells (lymphocytes) to stimulate the immune system for fighting leukemia/lymphoma was terminate…
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CLINICAL_TRIALS trial_result · 2015-06-24Clinical Trial Update: Disease Stabilization in AML by Treatment With ATRA, Valproic Acid and Low-dose Cytarabine [Phase 1, Phase 2]
A Phase 1/2 trial in Acute myeloid leukemia reports disease stabilization with a combination of all-trans retinoic acid, valproic acid, and …
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CLINICAL_TRIALS trial_result · 2015-06-24Clinical Trial Update: Differentiation Induction in Acute Myelogenous Leukemia [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial in acute myeloid leukemia sponsored by the University of Bergen has completed.
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CLINICAL_TRIALS trial_result · 2015-06-24Clinical Trial Update: A Study of Imatinib With Reinduction Chemotherapy Using Mitoxantrone, Etoposide and Cytarabine in Patients With Relapsed/Refractory C-kit Positive (AML) Acute Myeloid Leukemia [Phase 1, Phase 2]
A phase 1/2 study evaluating the combination of imatinib with reinduction chemotherapy (mitoxantrone, etoposide, cytarabine) in relapsed/ref…
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancy [Phase 1]
Phase 1 clinical trial evaluating the safety, tolerability, and biological activity of oral clioquinol in patients with relapsed or refracto…
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancy [Phase 1]
This Phase 1 clinical trial update reports the tolerance and biologic activity of oral ciclopirox olamine in patients with relapsed or refra…
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Safety and Efficacy Study of Nilotinib Combined With Mitoxantrone, Etoposide, and High-dose Cytarabine Induction Chemotherapy Followed by Consolidation for Patients With C-kit Positive Acute Myeloid Leukemia [Phase 1, Phase 2]
This terminated Phase 1/2 trial evaluated the safety and efficacy of adding nilotinib to a mitoxantrone, etoposide, and high-dose cytarabine…
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CLINICAL_TRIALS trial_result · 2015-06-19Clinical Trial Update: Cholecalciferol in Treating Patients With Acute Myeloid Leukemia Undergoing Intensive Induction Chemotherapy [Phase 2]
Phase 2 trial evaluating cholecalciferol (Vitamin D3) in adults with acute myeloid leukemia undergoing intensive induction chemotherapy; the…
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CLINICAL_TRIALS trial_result · 2015-06-19Clinical Trial Update: Maintenance Therapy in Acute Myeloid Leukemia (AML) Patients [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating maintenance therapy in patients with acute myeloid leukemia. The stu…
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Abdominal CT to Predict the Risk of Acute Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation [EARLY_Phase 1]
An early-phase study update reporting completion of a trial using abdominal CT to predict acute graft-versus-host disease risk after allogen…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: 5-Fluoro-2'-Deoxycytidine and Tetrahydrouridine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes [Phase 1]
Phase 1 trial assessing 5-Fluoro-2'-Deoxycytidine with tetrahydrouridine in adults with acute myeloid leukemia or myelodysplastic syndromes;…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Phase I Study of OPB-51602 in Patients With Hematologic Malignancies [Phase 1]
Phase I trial results are reported for OPB-51602 in patients with hematologic malignancies including multiple myeloma, non-Hodgkin lymphoma,…