Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-09-08Clinical Trial Update: Study of Azacitidine Combined With Homoharringtonie Based Regimens in AML [Phase 2]
A Phase 2 trial evaluating azacitidine in combination with homoharringtonine-based regimens for acute myeloid leukemia is reported as ongoin…
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CLINICAL_TRIALS trial_result · 2022-09-08Clinical Trial Update: Clinical Trial to Assess the Safety and Tolerability of the Combination of Low-dose Cytarabine or Azacitidine Plus Venetoclax and Quizartinib in Newly Diagnosed AML Patients Aged Equal or More Than 60 Years Old [Phase 1, Phase 2]
A Phase 1/2 trial evaluating safety and tolerability of combining low-dose cytarabine or azacitidine with venetoclax and quizartinib in newl…
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CLINICAL_TRIALS trial_result · 2022-09-02Clinical Trial Update: A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100) [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety and activity of pegylated recombinant human arginase (BCT-100) in pediatric cancers; study completed.
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CLINICAL_TRIALS trial_result · 2022-08-29Clinical Trial Update: A Study Evaluating Venetoclax in Combination With Low-Dose Cytarabine in Treatment-Naïve Participants With Acute Myelogenous Leukemia [Phase 1, Phase 2]
A study evaluating venetoclax with low-dose cytarabine in treatment-naïve acute myeloid leukemia participants has completed, with results po…
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CLINICAL_TRIALS trial_result · 2022-08-24Clinical Trial Update: Clinical Study Protocol of Venetoclax Combined With Azacitidine and Harringtonine in the Treatment of sAML [Phase 2]
Phase 2 clinical study protocol evaluating venetoclax with azacitidine and harringtonine for secondary acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2022-08-15Clinical Trial Update: Ruxolitinib Phosphate and Decitabine in Treating Patients With Relapsed or Refractory or Post Myeloproliferative Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 study evaluating the combination of ruxolitinib phosphate and decitabine in patients with relapsed or refractory or post-myeloprol…
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CLINICAL_TRIALS trial_result · 2022-08-08Clinical Trial Update: A Study of Brequinar in Subjects With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
A phase 1/2 trial of brequinar in relapsed/refractory acute myeloid leukemia (AML) was terminated with posted results in 2022.
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CLINICAL_TRIALS trial_result · 2022-08-05Clinical Trial Update: HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies [Phase 2]
Phase 2 clinical trial evaluating HLA-compatible related or unrelated donors with CD34+ enriched, T-cell depleted peripheral blood stem cell…
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CLINICAL_TRIALS trial_result · 2022-08-05Clinical Trial Update: Clinical Trial of Oral Ciprofloxacin and Etoposide in Subjects With Resistant Acute Myeloid Leukemia (AML)(UF-AML-CE-101) [Phase 1, Phase 2]
An early-phase clinical trial investigating oral ciprofloxacin and etoposide in resistant acute myeloid leukemia was terminated; results hav…
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CLINICAL_TRIALS trial_result · 2022-08-04Clinical Trial Update: Administration of Anti-siglec-6 CAR-T Cell Therapy in Relapsed and Refractory Acute Myeloid Leukemia (rr/AML) [Phase 1, Phase 2]
Early-phase trial of anti-Siglec-6 CAR-T therapy for relapsed/refractory acute myeloid leukemia is being investigated in Phase 1/2.
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CLINICAL_TRIALS trial_result · 2022-08-01Clinical Trial Update: Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Total Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial evaluating a combined regimen including iodine-131 monoclonal antibody BC8, fludarabine phosphate, total body irradia…
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CLINICAL_TRIALS trial_result · 2022-07-19Clinical Trial Update: Patients Receiving Induction With Liposomal Daunorubicin and Cytarabine (CPX-351) for Acute Myeloid Leukemia [Phase 4]
Phase 4 clinical trial update for CPX-351 (liposomal daunorubicin and cytarabine) in acute myeloid leukemia; study terminated with results p…
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CLINICAL_TRIALS trial_result · 2022-07-14Clinical Trial Update: VAH Versus VA for Salvage Therapy of R/R-AML [Phase 3]
A Phase 3 clinical trial comparing VAH versus VA as salvage therapy for relapsed/refractory acute myeloid leukemia, with venetoclax-azacitid…
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CLINICAL_TRIALS trial_result · 2022-07-05Clinical Trial Update: Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients [Phase 1, Phase 2]
Phase 1/2 trial evaluating decitabine with sequential rapamycin or ribavirin in high-risk acute myeloid leukemia completed; results posted i…
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CLINICAL_TRIALS trial_result · 2022-07-01Clinical Trial Update: Gemtuzumab Ozogamicin in Induction and Glasdegib in Postremission Therapy in Patients With AML (Acute Myeloid Leukemia) [Phase 3]
Phase 3 trial update for Gemtuzumab Ozogamicin in induction and Glasdegib in postremission therapy in acute myeloid leukemia has been termin…
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CLINICAL_TRIALS trial_result · 2022-06-28Clinical Trial Update: Efficacy and Safety of Decitabine as Epigenetic Priming With Induction Chemotherapy in Pediatric Acute Myelogenous Leukemia (AML) Subjects [Phase 2]
Phase 2 trial investigating decitabine as epigenetic priming with induction chemotherapy in pediatric acute myeloid leukemia; study terminat…
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CLINICAL_TRIALS trial_result · 2022-06-27Clinical Trial Update: A Study of ASP2215 (Gilteritinib), Administered as Maintenance Therapy Following Induction/Consolidation Therapy for Subjects With FMS-like Tyrosine Kinase 3 (FLT3/ITD) Acute Myeloid Leukemia (AML) in First Complete Remission [Phase 2]
Phase 2 trial evaluating gilteritinib as maintenance therapy after induction/consolidation in adults with FLT3-ITD acute myeloid leukemia in…
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CLINICAL_TRIALS trial_result · 2022-06-24Clinical Trial Update: A Study of ASP2215 (Gilteritinib) Combined With Atezolizumab in Patients With Relapsed or Treatment Refractory FMS-like Tyrosine Kinase (FLT3) Mutated Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 trial evaluating the combination of gilteritinib and atezolizumab in relapsed or FLT3-mutated acute myeloid leukemia. The study is…
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CLINICAL_TRIALS trial_result · 2022-06-23Clinical Trial Update: Decitabine and Talazoparib in Untreated AML and R/R AML [Phase 1, Phase 2]
Phase 1/2 trial evaluating decitabine with talazoparib in untreated and relapsed/refractory acute myeloid leukemia has completed with result…
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CLINICAL_TRIALS trial_result · 2022-06-23Clinical Trial Update: Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Previously Treated With Donor Stem Cell Transplant [Phase 1, Phase 2]
Phase 1/2 trial evaluating laboratory-treated T cells in relapsed hematologic malignancies after donor stem cell transplantation; trial term…
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CLINICAL_TRIALS trial_result · 2022-06-22Clinical Trial Update: A Study of Oral Sapacitabine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 3]
Phase 3 trial of oral sapacitabine in elderly patients with newly diagnosed acute myeloid leukemia has completed; results posted.
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CLINICAL_TRIALS trial_result · 2022-06-21Clinical Trial Update: A Study Evaluating the Safety and Efficacy of Idasanutlin in Combination With Cytarabine and Daunorubicin in Patients Newly Diagnosed With Acute Myeloid Leukemia (AML) and the Safety and Efficacy of Idasanutlin in the Maintenance of First AML Complete Remission [Phase 1, Phase 2]
Clinical trial evaluating idasanutlin in combination with cytarabine and daunorubicin in newly diagnosed AML and maintenance in first remiss…
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CLINICAL_TRIALS trial_result · 2022-06-21Clinical Trial Update: A Trial to Evaluate the Safety and Efficacy of oNKord® in Subjects With Acute Myeloid Leukemia [Phase 1, Phase 2]
Clinical trial update for oNKord in acute myeloid leukemia (Phase 1/Phase 2) evaluating safety and efficacy.
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CLINICAL_TRIALS trial_result · 2022-06-15Clinical Trial Update: AflacLL1901 (CHOA-AML) [Phase 2]
Phase 2 clinical trial update for AflacLL1901 (CHOA-AML) in childhood acute myeloid leukemia; the study has been terminated with results pos…
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CLINICAL_TRIALS trial_result · 2022-06-03Clinical Trial Update: A Study of CPX-351 (Vyxeos™) With Quizartinib for the Treatment of FLT3-ITD Mutation-Positive Acute Myeloid Leukemia [Phase 2]
Phase 2 trial update of CPX-351 (Vyxeos) combined with quizartinib for FLT3-ITD positive acute myeloid leukemia (AML) has been terminated wi…