Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial update evaluating a combination of venetoclax, decitabine, and cedazuridine for relapsed or refractory acute myeloi…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update. It evaluates a conditioning strategy using chemotherapy, total body irradiation, and post-transpl…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms [Phase 1]
Phase 1 study evaluating FLAG-Ida chemotherapy plus pivekimab sunirine (IMGN632) for newly diagnosed adverse-risk acute myeloid leukemia and…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Multi-Site Break Through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib [Phase 1, Phase 2]
A multi-site Phase I/II trial at MD Anderson Cancer Center is evaluating the combination of venetoclax (BCL-2 inhibitor) and revumenib (meni…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia [Phase 1]
A Phase 1 pediatric trial aims to identify the highest tolerated dose of a cedazuridine-decitabine combination with filgrastim after hematop…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Testing the Combination of Targeted Radiotherapy With Anti-Cancer Drugs, Venetoclax and ASTX-727, to Improve Outcomes for Adults With Newly Diagnosed Acute Myeloid Leukemia [Phase 1]
This Phase 1 clinical trial investigates the combination of targeted radiotherapy with Venetoclax and ASTX-727 for adults with newly diagnos…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) [Phase 1, Phase 2]
Phase I/II trial evaluating an engineered donor graft named Orca Q for pediatric hematopoietic cell transplantation is currently suspended. …
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring [Phase 1]
Phase 1 rollover study by Janssen Research & Development to continue study treatment and ongoing safety monitoring in patients with acute my…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Decitabine, Cytarabine, and Daunorubicin Hydrochloride in Treating Patients With Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial evaluating the combination of decitabine, cytarabine, and daunorubicin hydrochloride for treatment of Acute Myeloid…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Venetoclax or Placebo in Combination With Reduced-Intensity Conditioning Hematopoietic Cell (Bone Marrow/Blood Stem Cell) Transplant and as Maintenance Therapy After Transplant in Patients With Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial) [Phase 2]
A Phase 2 clinical trial evaluating venetoclax or placebo with reduced-intensity conditioning hematopoietic cell transplant followed by main…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Study of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AML [Phase 3]
A Phase 3 trial comparing crenolanib to midostaurin after induction and consolidation chemotherapy in newly diagnosed FLT3-mutated acute mye…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: High-dose Ascorbate (HDA) in Combination With Standard of Care Azacitidine and Venetoclax in Acute Myeloid Leukemia (AML) [Phase 1]
This Phase 1 clinical trial is evaluating high-dose ascorbate in combination with azacitidine and venetoclax for Acute Myeloid Leukemia. The…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: A Phase 1, Open-Label, Sequential Cross-over, Bioavailability/Bioequivalence Study to Compare the Pharmacokinetics of Oral Cladribine With the Reference Listed Drug, Intravenous Cladribine [Phase 1]
Phase 1 open-label bioavailability study comparing pharmacokinetics of oral cladribine with intravenous cladribine. The study status is TERM…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Phase I Clinical Trial of ThINKK Adoptive Immunotherapy After Allogeneic Hematopoietic Transplantation in Children With Leukemia or Neuroblastoma [Phase 1]
Phase I clinical trial update for ThINKK Adoptive Immunotherapy after allogeneic hematopoietic stem cell transplantation in children with ac…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial evaluating AOH1996 in relapsed or refractory acute myeloid leukemia is currently suspended.
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Vyxeos for Re-induction Treatment of Acute Myeloid Leukemia Patients With Persistent Disease After Induction [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating Vyxeos as re-induction therapy for acute myeloid leukemia in patients with persistent disease af…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Azacitidine and Venetoclax as Induction Therapy With Venetoclax Maintenance in the Elderly With AML [Phase 2]
Phase 2 study evaluating induction therapy with azacitidine and venetoclax followed by venetoclax maintenance in elderly patients with acute…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: High- Fiber/ Low-fat Diet for Prevention of Recurrent Clostridioides Difficile Infection in Oncology [NA]
A completed clinical trial examined whether a high-fiber, low-fat diet can prevent recurrent Clostridioides difficile infection in oncology …
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies [Phase 1]
Phase 1 safety trial update for SEA-CD70 in myeloid malignancies; the study in myelodysplastic syndrome and acute myeloid leukemia is curren…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Prophylactic and Therapeutic DLI-X for Leukemia Relapse After HCT [Phase 1]
Phase 1 clinical trial update on DLI-X as a prophylactic and therapeutic donor lymphocyte infusion to prevent or treat leukemia relapse afte…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study [NA]
Completed clinical trial evaluating a geriatric optimization plan to improve survival in older adults undergoing allogeneic hematopoietic ce…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Axatilimab Combined With Decitabine/Venetoclax for the Treatment of TP53-mutated AML [Phase 1]
Phase 1 trial exploring axatilimab with decitabine and venetoclax for TP53-mutated acute myeloid leukemia; the study status is not yet recru…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Gentulizumab in Relapsed/Refractory Acute Myelogenous Leukemia or Myelodysplastic Syndrome [Phase 1]
A Phase 1 study of Gentulizumab in relapsed/refractory acute myeloid leukemia or myelodysplastic syndromes has been terminated.
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed/Refractory Hematologic Malignancies [Phase 1, Phase 2]
A completed Phase 1/2 study evaluating CTX131 in adults with relapsed or refractory hematologic malignancies, assessing safety and efficacy …
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
This clinical trials update covers a Phase I/II study of the MUC1 inhibitor GO-203-2C in adults with relapsed or refractory acute myeloid le…