Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: 3-AP and High-Dose Cytarabine in Treating Patients With Advanced Hematologic Malignancies [Phase 1]
Phase 1 trial evaluating the combination of triapine (3-AP) with high-dose cytarabine in adults with advanced hematologic malignancies has c…
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: PS-341 in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia in Blast Phase, or Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial update (completed) of PS-341 (bortezomib) in patients with refractory or relapsed acute myeloid leukemia, acute lymph…
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: Rebeccamycin Analog in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia [Phase 1]
Phase 1 study evaluating a rebeccamycin analog in adults with relapsed or refractory acute myeloid leukemia, myelodysplastic syndromes, acut…
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: CCI-779 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, or Chronic Myelogenous Leukemia in Blastic Phase [Phase 2]
A Phase 2 trial evaluating CCI-779 (temsirolimus) in adults with relapsed or refractory acute myeloid leukemia, acute lymphoblastic leukemia…
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: BMS-214662 in Treating Patients With Acute Leukemia, Myelodysplastic Syndrome, or Chronic Myeloid Leukemia [Phase 1]
Phase 1 study of BMS-214662 in patients with various leukemias and myelodysplastic syndromes has completed enrollment; the document lists th…
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: Decitabine in Treating Children With Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia [Phase 1]
A Phase 1 pediatric trial evaluates decitabine for relapsed or refractory acute myeloid leukemia and acute lymphoblastic leukemia, including…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Raltitrexed in Treating Children With Refractory Acute Leukemia [Phase 1]
This document provides an update on a Phase 1 clinical trial of Raltitrexed for refractory acute leukemia in children, including recurrent c…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [NA]
Completed clinical trial evaluating a combination chemotherapy regimen for newly diagnosed pediatric acute lymphoblastic leukemia, including…
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CLINICAL_TRIALS trial_result · 2013-01-11Clinical Trial Update: SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic Syndromes [Phase 1]
This Phase 1 trial evaluated SB-715992 in adults with various acute leukemias, chronic myeloid leukemia in blast phase, and advanced myelody…
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CLINICAL_TRIALS trial_result · 2013-01-11Clinical Trial Update: Pharmacokinetic Profile of Vincristine Administered With Imatinib for Bcr-Abl Positive Acute Lymphoblastic Leukemia (ALL) Compared to That Without Imatinib for Bcr-Abl Negative ALL
A terminated clinical trial comparing the pharmacokinetic profile of vincristine when given with imatinib in BCR-ABL positive acute lymphobl…
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CLINICAL_TRIALS research · 2013-01-11Clinical Trial Update: Quality of Life Study for Adult Patients With Acute Lymphoblastic Leukemia
A completed quality of life study in adult patients with Acute Lymphoblastic Leukemia, sponsored by the University Health Network in Toronto…
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: Sorafenib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Chronic Myelogenous Leukemia [Phase 1]
A Phase 1 trial evaluating sorafenib in adults with relapsed or refractory acute myeloid leukemia, acute lymphoblastic leukemia, or chronic …
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CLINICAL_TRIALS trial_result · 2013-01-08Clinical Trial Update: Dasatinib in Treating Patients With Chronic Myelogenous Leukemia or Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 clinical trial evaluating dasatinib in patients with chronic myeloid leukemia or acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2013-01-07Clinical Trial Update: Vorinostat and Decitabine in Treating Patients With Relapsed, Refractory, or Poor-Prognosis Hematologic Cancer or Other Diseases [Phase 1]
This Phase 1 trial evaluates the safety and feasibility of combining vorinostat with decitabine in adults with relapsed, refractory, or poor…
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FDA approval · 2012-12-20FDA Approved: TASIGNA — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for Tasigna (nilotinib) submitted by Novartis Pharmaceuticals Corporation. The action typically upda…
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FDA approval · 2012-12-14FDA Approved: ICLUSIG — Original Application (Takeda Pharmaceuticals America, Inc.)
This FDA page documents the original approval of ICLUSIG (ponatinib hydrochloride) by Takeda Pharmaceuticals America, Inc.
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CLINICAL_TRIALS trial_result · 2012-12-07Clinical Trial Update: Reduced Intensity Donor Stem Cell Transplant in Treating Patients With High Risk Acute Lymphocytic Leukemia in Complete Remission [Phase 2]
Phase 2 study of reduced-intensity conditioning followed by donor stem cell transplant for high-risk acute lymphoblastic leukemia in complet…
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CLINICAL_TRIALS trial_result · 2012-12-07Clinical Trial Update: Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated Donor [Phase 2]
Phase 2 study evaluating parathyroid hormone after sequential cord blood transplantation from an unrelated donor; the trial was terminated a…
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CLINICAL_TRIALS trial_result · 2012-11-29Clinical Trial Update: Safety and Efficacy of Marqibo in Relapsed Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial update for Marqibo in relapsed acute lymphoblastic leukemia completed with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-11-09Clinical Trial Update: Non-Myeloablative Allogeneic Stem Cell Transplantation With Matched Unrelated Donors for Treatment of Hematologic Malignancies, Renal Cell Carcinoma, and Aplastic Anemia
This clinical trial evaluated non-myeloablative allogeneic stem cell transplantation with matched unrelated donors across several hematologi…
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CLINICAL_TRIALS withdrawal · 2012-11-08Clinical Trial Update: Bendamustine in Acute Lymphoblastic Leukemia/Lymphoma (ALL) [Phase 2]
A Phase 2 trial evaluating bendamustine for acute lymphoblastic leukemia and lymphoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-10-19Clinical Trial Update: Bendamustine in Acute Leukemia and MDS [Phase 1, Phase 2]
Phase 1/2 trial of bendamustine in acute leukemia and myelodysplastic syndromes was terminated with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-10-10Clinical Trial Update: Liposomal Cytarabine for Central Nervous System (CNS)-Treatment in High-risk Acute Lymphoblastic Leukemia (ALL) [Phase 3]
A Phase 3 trial evaluating liposomal cytarabine for central nervous system treatment in high-risk acute lymphoblastic leukemia has been susp…
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Combination Chemotherapy in Treating Children With Relapsed or Refractory Acute Lymphocytic Leukemia [Phase 2]
This clinical trial update reports the termination of a Phase 2 study evaluating a combination chemotherapy regimen for children with relaps…
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CLINICAL_TRIALS safety_alert · 2012-09-12Clinical Trial Update: Thromboembolic Complications Related to Asparaginase in Children With Acute Lymphoblastic Leukemia (ALL) Treated According to NOPHO ALL 2008
This clinical trial update discusses thromboembolic complications related to asparaginase in children with acute lymphoblastic leukemia trea…