Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancers [Phase 2]
Phase 2 trial evaluating cord blood transplant with Dilanubicel for HIV-positive hematologic cancers; the study was terminated and results w…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors [Phase 1, Phase 2]
Clinical trial evaluating idasanutlin in combination with chemotherapy or venetoclax in pediatric and young adult relapsed/refractory acute …
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Animal Assisted Interactions With Animal Robot in the Intensive Care Unit (ICU) [NA]
A completed clinical trial evaluating animal-assisted interactions using an animal robot in the ICU; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Prehospital Provider Training With Augmented Reality (AR) [NA]
A clinical trial evaluating prehospital provider training with augmented reality has completed. The provided snippet does not include effica…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Fludarabine, Cytarabine, and Pegcrisantaspase for the Treament of Relapsed or Refractory Leukemia [Phase 1]
Phase 1 trial of fludarabine, cytarabine, and pegcrisantaspase for relapsed or refractory leukemias was terminated; the update notes the stu…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: Clofarabine or High-Dose Cytarabine and Pegaspargase in Children with ALL [Phase 2, Phase 3]
A phase 2/phase 3 trial evaluated clofarabine or high-dose cytarabine in combination with pegaspargase for children with acute lymphoblastic…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: T-cell Receptor α/β Depleted Donor Lymphocyte Infusion [Phase 1]
Phase 1 trial of T-cell receptor α/β-depleted donor lymphocyte infusion was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Administration of Donor MultiTAA-Specific T Cells for ALL [Phase 1]
This update reports the completion of a Phase 1 study evaluating donor multi-TAA-specific T cells for acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies [Phase 1]
Phase 1 clinical trial studying tagraxofusp in pediatric patients with CD123-expressing hematologic malignancies is currently recruiting, sp…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Study of Sequential CAR-T Cell Treating Leukemia Children [Phase 2]
A Phase 2 trial of sequential CAR-T cell therapy for pediatric acute lymphoblastic leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: WT1 Vaccine Treatment of Patients in Remission From Acute Myeloid Leukemia (AML) or Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase 2 trial evaluating the WT1 vaccine in patients in remission from acute myeloid leukemia or acute lymphoblastic leukemia has completed …
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Singapore's Health Outcomes After Critical Illness in Kids
This completed study at KK Women's and Children's Hospital in Singapore evaluates health outcomes in children— including those with pediatri…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial update on a Triplex CMV vaccine designed to prevent CMV infection in patients undergoing hematopoietic stem cell tran…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating CD19-specific CAR-engineered autologous T cells for relapsed or refractory CD19-positive acute lymphoblastic leuk…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Effects of Home-Based Exercise Program in Children After Acute Lymphoblastic Leukemia [NA]
This clinical trial update reports on a completed study evaluating a home-based exercise program in children after acute lymphoblastic leuke…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Cytomegalovirus (CMV) Vaccine in Donors and Recipients Undergoing Allogeneic Hematopoietic Cell Transplant (HCT) [Phase 2]
Phase 2 trial of a cytomegalovirus vaccine for donors and recipients undergoing allogeneic hematopoietic cell transplantation has completed,…
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CLINICAL_TRIALS trial_result · 2024-10-17Clinical Trial Update: CD34 Selected Allogeneic HCT w/ Myeloablative Conditioning Plus CD8+ Memory TCell Infusion in MDS, AL and CML [Phase 2]
Phase 2 clinical trial evaluating CD34-selected allogeneic hematopoietic stem cell transplantation with myeloablative conditioning plus CD8+…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia [Phase 1]
A Phase 1 study evaluating the safety and potential efficacy of combining blinatumomab with nivolumab, with or without ipilimumab, in patien…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Use of Integrated Pulmonary Index Monitorisation in Children Undergoing Botulinum Toxin Injection [NA]
This completed clinical trial evaluated integrated pulmonary index monitoring during botulinum toxin injections in children, including those…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Cardiovascular Function in Acute Leukemia
A completed clinical trial update evaluating cardiovascular function and potential cardiotoxicity in patients with acute leukemia.
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: Applying Pediatric Nursing Excellence Model to Nurses in Orthopedic Surgery Care of Children [NA]
The completed study evaluates applying the Pediatric Nursing Excellence Model to nurses caring for children undergoing orthopedic surgery, f…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 trial evaluating combination chemotherapy with or without blinatumomab in newly diagnosed BCR-ABL-negative B-ALL; status active not …
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 trial evaluating addition of blinatumomab to standard chemotherapy in newly diagnosed BCR-ABL-negative B-lineage acute lymphoblastic…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Phase I Study of CYC140, a PLK-1 Inhibitor, in Advanced Leukemias or MDS [Phase 1]
Phase I study of CYC140, a PLK-1 inhibitor, in advanced leukemias and myelodysplastic syndromes has been terminated.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Blinatumomab Added to Prephase and Consolidation Therapy in Precursor B-acute Lymphoblastic Leukemia in Adults. [Phase 2]
Phase 2 study in adults with precursor B-cell acute lymphoblastic leukemia adds blinatumomab to prephase and consolidation therapy.