Acute Lymphoblastic Leukemia
📧 Sign up to get email alerts when something new happens for Acute Lymphoblastic Leukemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma [Phase 1, Phase 2]
This clinical trial update summarizes the Phase 1/2 results of oral ixazomib in combination with chemotherapy for pediatric patients with re…
-
CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases [Phase 2]
A Phase 2 clinical trial is testing alpha/beta T cell and CD19+ B cell depletion in allogeneic stem cell transplantation for malignant disea…
-
CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: ALL Adult Consortium Trial: Adult ALL Trial [Phase 2]
A Phase 2 trial in adults with acute lymphoblastic leukemia (ALL) completed for the ALL Adult Consortium; results have been posted.
-
CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Insomnia Prevention in Children With Acute Lymphoblastic Leukemia [NA]
Completed clinical trial investigating insomnia prevention in children with acute lymphoblastic leukemia; results have been posted on 2025-0…
-
CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 trial results update for carfilzomib in combination with induction chemotherapy in children with relapsed or refractory acute lympho…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies [Phase 1]
Phase 1 study evaluating CD19/CD22 CAR T cells in children and young adults with recurrent or refractory CD19/CD22-expressing B cell maligna…
-
CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD [Phase 2]
Phase 2 clinical trial assessing selective depletion of CD45RA+ T cells from allogeneic stem cell grafts to prevent graft-versus-host diseas…
-
CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation [Phase 2]
Phase 2 trial comparing three GVHD prophylaxis regimens in nonmyeloablative or reduced-intensity conditioning unrelated donor transplantatio…
-
CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Expanded Access to Ziftomenib
Kura Oncology announces expanded access to the investigational menin inhibitor ziftomenib for eligible patients with acute lymphoblastic leu…
-
CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: CD19 CAR T Cells in Patients With Resistant or Refractory CD19+ Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 study of CD19-directed CAR T cells in patients with resistant or refractory CD19-positive acute lymphoblastic leukemia has completed…
-
CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: A Triple-targeted Cell Preparation Targeting CD19/CD20/CD22 in Patients With Relapsed/Refractory B-cell Acute Lymphocytic Leukemia [Phase 1]
A Phase 1 trial of a triple-targeted CD19/CD20/CD22 CAR-T cell therapy for relapsed/refractory B-cell acute lymphoblastic leukemia has been …
-
CLINICAL_TRIALS trial_result · 2025-05-23Clinical Trial Update: DS-1594b With or Without Azacitidine, Venetoclax, or Mini-HCVD for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
A phase 1/2 study of DS-1594b with or without azacitidine, venetoclax, or mini-HCVD in relapsed or refractory acute myeloid leukemia or acut…
-
CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Supporting Parents to Choose Wisely [NA]
A completed University of Alberta clinical trial evaluated decision-support tools to help parents choose care for children with several comm…
-
CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Study of Anti-CD22 CAR-T Cells Treating Leukemia Children [Phase 2]
A Phase 2 clinical trial evaluating anti-CD22 CAR-T cells for pediatric acute lymphoblastic leukemia has completed, including relapsed and r…
-
CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Phase II Study of Anti-CD19 CAR-T Cells Treating Leukemia Children [Phase 2]
Phase II trial evaluating anti-CD19 CAR-T cell therapy for pediatric acute lymphoblastic leukemia, including relapsed and refractory cases; …
-
CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Feasibility Study to Evaluate Outpatient Blinatumomab in Subjects With Minimal Residual Disease (MRD) of B-precursor Acute Lymphoblastic Leukemia (ALL) [Phase 4]
A Phase 4 feasibility trial evaluating outpatient administration of blinatumomab in patients with minimal residual disease in B-cell precurs…
-
CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Study of huCART19 for Very High-Risk (VHR) Subsets of Pediatric B-ALL [Phase 2]
A Phase 2 study evaluating huCART19 for very high-risk pediatric B-cell acute lymphoblastic leukemia has completed and results have been pos…
-
CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Augmentation of the Graft vs. Leukemia Effect Via Checkpoint Blockade With Pembrolizumab [Phase 1]
Phase 1 study evaluating pembrolizumab to augment graft-versus-leukemia effect in patients with myelodysplastic syndromes and acute myeloid …
-
CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: Accuracy Performance Verification of the INVOS™ System in Pediatrics
A completed clinical trial evaluating the accuracy of the INVOS System for measuring cerebral oxygenation in pediatric patients, including t…
-
CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Venetoclax, Ponatinib, and Dexamethasone in Participants With Philadelphia Chromosome or BCR-ABL Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia [Phase 1, Phase 2]
A Phase 1/2 study evaluating venetoclax, ponatinib, and dexamethasone in patients with BCR-ABL1 positive Philadelphia chromosome positive re…
-
CLINICAL_TRIALS trial_result · 2025-05-01Clinical Trial Update: Flumatinib Versus Imatinib Combined With Chemotherapy for de Novo Ph+ ALL [Phase 4]
Phase 4 clinical trial comparing flumatinib versus imatinib in combination with chemotherapy for newly diagnosed Philadelphia chromosome-pos…
-
CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood Transplantation [Phase 2]
Phase 2 trial evaluating tocilizumab to prevent graft-versus-host disease after cord blood transplantation has been completed.
-
CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: A Study to Evaluate the Long-term Safety of Patients With Advanced Lymphoid Leukemia Who Have Been Previously Administered With UCART19 [Phase 1]
A Phase 1 long-term safety study of UCART19 in patients with advanced lymphoid leukemia is ongoing (status: ACTIVE_NOT_RECRUITING).
-
CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation [Phase 1]
Phase 1 study evaluating itacitinib for prophylaxis of graft-versus-host disease and cytokine release syndrome after T-cell replete haploide…
-
CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched Donors [Phase 2]
A Phase 2 trial evaluating α/β+-T lymphocyte-depleted donor grafts from HLA-mismatched donors in multiple hematologic malignancies was termi…