Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: A Bioavailability Study of Nilotinib in Healthy, Adult, Human Subjects Under Fasted Conditions. [Phase 1]
A Phase 1 bioavailability study of nilotinib in healthy adult participants under fasted conditions has been completed.
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Squishy Toy and Palpation in Pediatric IV Success [NA]
A completed clinical trial from Akdeniz University evaluating a squishy toy-assisted palpation technique to improve intravenous access succe…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Ciprofloxacin vs Ceftazidime for Empirical Treatment of High-Risk Neutropenic Fever in Children With Hematologic Malignancies [Phase 4]
Phase 4 trial comparing ciprofloxacin to ceftazidime as empirical therapy for high-risk febrile neutropenia in children with hematologic can…
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell [Phase 1, Phase 2]
A completed Phase 1/2 study from Stanford evaluated a haploidentical hematopoietic cell transplantation approach using a T-cell depleted gra…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Safety and Feasibility of CD19 CAR T Cells Using CliniMACS Prodigy for Relapsed/Refractory CD19 Positive ALL and NHL [EARLY_Phase 1]
An early-phase trial evaluating the safety and feasibility of CD19 CAR T cells manufactured with the CliniMACS Prodigy platform for relapsed…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Incidence of Invasive Fungal Infections Among Patients With Acute Lymphoblastic Leukemia Ph-negative
Clinical trial update noting ongoing recruitment for a study assessing the incidence of invasive fungal infections in adults with Ph-negativ…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Tagraxofusp and Low-Intensity Chemotherapy for the Treatment of CD123 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating tagraxofusp in combination with low-intensity chemotherapy for CD123-positive relapsed or refractory acute lympho…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Long-term Follow-up of Patients Treated With Genetically Modified Autologous T Cells [Phase 2]
This clinical trial update reports long-term follow-up data from patients treated with Autolus' autologous CAR T cell therapy in multiple my…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: A Study of Inotuzumab Ozogamicin in Chinese Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 4]
Pfizer's Phase 4 trial of Inotuzumab Ozogamicin in Chinese patients with relapsed or refractory acute lymphoblastic leukemia has completed a…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]
Phase 2 clinical trial evaluating HLA-mismatched unrelated donor bone marrow transplantation with post-transplant cyclophosphamide; the stud…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Study of Escalating Doses of INA03 Administered Intravenously as Single Agent in Adult Patients With Relapse/Refractory Acute Leukemia [EARLY_Phase 1]
An early-phase 1 study evaluated escalating intravenous doses of INA03 as a single agent in adults with relapsed or refractory acute leukemi…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Impact of Low-intensity Chemotherapy Combined With Short-course Blinatumomab on Allo-HSCT in Adults With Ph- B-ALL [Phase 2]
Phase 2 trial update examining whether adding low-intensity chemotherapy to a short course of blinatumomab improves outcomes for adults with…
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial evaluating 225Ac-DOTA-Anti-CD38 (daratumumab radiolabeled with Actinium-225) in combination with fludarabine, melphal…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Haplo Peripheral Blood Sct In GVHD Prevention [Phase 1]
Phase 1 trial update reporting the completion of a haploidentical peripheral blood stem cell transplantation approach for the prevention of …
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Total Marrow and Lymphoid Irradiation and Chemotherapy Before DSCT in Treating Patients With High-Risk ALL or AML [Phase 2]
Phase 2 trial update evaluating total marrow and lymphoid irradiation plus chemotherapy before donor stem cell transplantation in high-risk …
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene [Phase 1]
Phase 1 clinical trial of CASPALLO allodepleted T cells engineered with an inducible caspase-9 suicide gene; the study is currently active b…
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Telemedicine Optimized Burn Intervention [NA]
Completed clinical trial evaluating a telemedicine-optimized burn intervention. Results have been posted for conditions including burn injur…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCT [Phase 2]
This Phase 2 trial comparing post-transplant cyclophosphamide (PTCy) plus ruxolitinib versus PTCy with tacrolimus and MMF in matched related…
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CLINICAL_TRIALS trial_result · 2025-07-04Clinical Trial Update: UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep [Phase 2]
Phase 2 clinical trial evaluating non-myeloablative preparative regimens followed by umbilical cord blood transplantation for various hemato…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Human AntiCD19 Chimeric Antigen Receptor T Cells for Relapsed or Refractory Lymphoid Malignancies [Phase 1]
Phase 1 clinical trial evaluating human anti-CD19 CAR-T cells for relapsed or refractory lymphoid malignancies is currently active but not r…
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: CD19.CAR Allogeneic NKT for Patients With Relapsed or Refractory B-Cell Malignancies (ANCHOR) [Phase 1]
Phase 1 study update for CD19 CAR-allogeneic NKT therapy (ANCHOR) in relapsed or refractory B-cell malignancies; the trial is currently acti…
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: A Real-world Study of the Effectiveness of Tisagenlecleucel in Acute Lymphoblastic Leukemia Patients
This clinical trial update summarizes real-world effectiveness data for tisagenlecleucel in patients with acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: CAR-Multicenter Analysis (CAR-MA): Retrospective Study to Characterize CAR T-cell Outcomes and Related Toxicities in Children and Young Adults With B-ALL
Multicenter retrospective analysis assessing CAR T-cell therapy outcomes and related toxicities in children and young adults with B-cell acu…
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Biology and Benefits of Music Play and Stories for Kids/Parents During ALL Treatment [NA]
A completed clinical trial evaluating the biology and benefits of music play and storytelling for children undergoing treatment for acute ly…
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia [Phase 1]
A Phase 1 clinical trial evaluating total marrow and lymphoid irradiation with chemotherapy before donor transplantation in patients with my…