Acute Lymphoblastic Leukemia

• CLINICAL_TRIALS trial_result · 2013-10-16
  Clinical Trial Update: Chemotherapy With or Without Total-Body Irradiation Prior to Bone Marrow Transplantation in Treating Children With Acute Lymphoblastic Leukemia [Phase 3]

  A Phase 3 study examining chemotherapy with or without total-body irradiation before bone marrow transplantation in children with acute lymp…

• CLINICAL_TRIALS trial_result · 2013-10-08
  Clinical Trial Update: Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Acute Leukemia [Phase 1, Phase 2]

  This document reports the completion of a Phase 1/2 clinical trial evaluating the combination of flavopiridol, cytarabine, and mitoxantrone …

• CLINICAL_TRIALS trial_result · 2013-09-30
  Clinical Trial Update: Vorinostat and Idarubicin in Treating Patients With Relapsed or Refractory Leukemia or Myelodysplastic Syndromes [Phase 1]

  A Phase 1 study evaluating the combination of vorinostat with idarubicin in patients with relapsed or refractory leukemia or myelodysplastic…

• CLINICAL_TRIALS trial_result · 2013-09-30
  Clinical Trial Update: Tanespimycin and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, Chronic Myelomonocytic Leukemia, or Myelodysplastic Syndromes [Phase 1]

  Phase 1 trial evaluating Tanespimycin in combination with Cytarabine in adults with relapsed or refractory acute myeloid leukemia, acute lym…

• CLINICAL_TRIALS trial_result · 2013-09-30
  Clinical Trial Update: 7-Hydroxystaurosporine and Perifosine in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia or High Risk Myelodysplastic Syndromes [Phase 1]

  Phase 1 trial of the combination therapy 7-Hydroxystaurosporine and perifosine in adults with relapsed or refractory acute leukemias, chroni…

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• CLINICAL_TRIALS trial_result · 2013-09-30
  Clinical Trial Update: Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Relapsed or Refractory Acute Leukemia [Phase 1]

  A Phase 1 trial evaluating flavopiridol with cytarabine and mitoxantrone in adults with relapsed or refractory acute leukemia; the study has…

• CLINICAL_TRIALS trial_result · 2013-09-30
  Clinical Trial Update: SJG-136 in Treating Patients With Relapsed or Refractory Acute Leukemia, Myelodysplastic Syndromes, Blastic Phase Chronic Myelogenous Leukemia, or Chronic Lymphocytic Leukemia [Phase 1]

  Phase 1 trial of SJG-136 in relapsed or refractory hematologic cancers (acute myeloid leukemia subtypes, myelodysplastic syndromes, blast-ph…

• CLINICAL_TRIALS trial_result · 2013-08-28
  Clinical Trial Update: Haploidentical Natural Killer (NK) Cells With Epratuzumab for Relapsed Acute Lymphoblastic Leukemia (ALL) [Phase 2]

  This is a Phase 2 trial evaluating haploidentical natural killer cells with epratuzumab for relapsed acute lymphoblastic leukemia; the study…

• CLINICAL_TRIALS trial_result · 2013-08-28
  Clinical Trial Update: Irinotecan, Vincristine, and Dexamethasone In Children With Relapsed And/Or Refractory Hematologic Malignancies [Phase 1]

  A phase 1 trial from St. Jude Children’s Research Hospital evaluates irinotecan with vincristine and dexamethasone in children with relapsed…

• CLINICAL_TRIALS trial_result · 2013-08-27
  Clinical Trial Update: Utility of XCL1 as a Prognostic Marker in Acute Lymphoblastic Leukemia

  This clinical trial update reports on the completed study evaluating XCL1 as a prognostic biomarker in acute lymphoblastic leukemia.

• CLINICAL_TRIALS trial_result · 2013-08-26
  Clinical Trial Update: Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia [Phase 3]

  Completed Phase 3 trial evaluating combination chemotherapy for children with acute lymphoblastic leukemia.

• CLINICAL_TRIALS trial_result · 2013-08-26
  Clinical Trial Update: Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia [NA]

  This trial update discusses a study evaluating combination chemotherapy for young patients with acute lymphoblastic leukemia.

• CLINICAL_TRIALS trial_result · 2013-08-22
  Clinical Trial Update: Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia [Phase 3]

  Phase 3 clinical trial completed evaluating combination chemotherapy in children with relapsed acute lymphoblastic leukemia.

• CLINICAL_TRIALS trial_result · 2013-08-21
  Clinical Trial Update: Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia [Phase 3]

  Phase 3 clinical trial evaluating a combination chemotherapy regimen for non-Hodgkin lymphoma or acute lymphoblastic leukemia; the study has…

• CLINICAL_TRIALS trial_result · 2013-08-14
  Clinical Trial Update: Pilot Study of Umbilical Cord Blood Transplantation in Adult Patient With Advanced Hematopoietic Malignancies [NA]

  This clinical trial update indicates that a pilot study of umbilical cord blood transplantation in adults with advanced hematopoietic malign…

• CLINICAL_TRIALS trial_result · 2013-08-12
  Clinical Trial Update: Combination Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 3]

  This update notes the completion of a Phase 3 study evaluating combination chemotherapy in young patients with relapsed or refractory acute …

• CLINICAL_TRIALS trial_result · 2013-08-07
  Clinical Trial Update: Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia [Phase 2]

  Phase 2 clinical trial update evaluating combination chemotherapy for relapsed or refractory acute lymphoblastic leukemia.

• CLINICAL_TRIALS trial_result · 2013-08-02
  Clinical Trial Update: Pilot Study of Reduced-Intensity Umbilical Cord Blood Transplantation in Adult Patients Wtih Advanced Hematopoietic Malignancies

  The trial evaluating reduced-intensity umbilical cord blood transplantation in adults with advanced hematopoietic malignancies has been term…

• CLINICAL_TRIALS trial_result · 2013-08-02
  Clinical Trial Update: Unrelated Stem Cell Transplantation for Adults With Hematopoietic Disorders

  This clinical trial update notes the completion of an unrelated donor stem cell transplantation study in adults with hematopoietic disorders…

• CLINICAL_TRIALS trial_result · 2013-07-16
  Clinical Trial Update: Pilot Study of Haploidentical Natural Killer Cell Infusions for Poor Prognosis Non-AML Hematologic Malignancies [Phase 1]

  Phase 1 pilot study evaluating haploidentical natural killer cell infusions for poor-prognosis non-AML hematologic malignancies has complete…

• CLINICAL_TRIALS trial_result · 2013-07-10
  Clinical Trial Update: Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Relapsed Acute Lymphocytic Leukemia [Phase 2]

  A Phase 2 trial evaluating combination chemotherapy followed by peripheral stem cell transplantation in children with relapsed acute lymphob…

• CLINICAL_TRIALS trial_result · 2013-07-02
  Clinical Trial Update: A Phase 1 Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies [Phase 1]

  A Phase 1 dose-escalation study of TAK-901 in subjects with advanced hematologic malignancies; the trial has completed.

• CLINICAL_TRIALS trial_result · 2013-06-28
  Clinical Trial Update: Pharmacokinetic Study of Doxorubicin in Children With Cancer [Phase 2]

  A completed Phase 2 pharmacokinetic study of doxorubicin in pediatric cancer patients, providing pharmacokinetic data for children with Wilm…

• CLINICAL_TRIALS trial_result · 2013-06-26
  Clinical Trial Update: Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia [Phase 1, Phase 2]

  A Phase 1/2 clinical trial comparing combination chemotherapy followed by peripheral stem cell transplantation versus isotretinoin in patien…

• CLINICAL_TRIALS trial_result · 2013-06-26
  Clinical Trial Update: The Influence of Thiopurine Methyltransferase Activity on Toxicity After High-dose Methotrexate in Childhood Acute Lymphoblastic Leukemia

  The study investigates whether thiopurine methyltransferase (TPMT) activity affects toxicity from high-dose methotrexate in pediatric acute …