Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-09-30Clinical Trial Update: Resistance to Methotrexate in Patients With Acute Lymphoblastic Leukemia in Relapse or Remission
This completed clinical trial evaluated resistance to methotrexate in patients with acute lymphoblastic leukemia who were in relapse or remi…
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord Unit [Phase 2]
Phase 2 clinical trial evaluating hematopoietic stem cell transplantation using a CD34-selected mismatched related donor plus one umbilical …
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Rituximab in Treating Young Patients Who Are Receiving Chemotherapy for B-Cell Non-Hodgkin's Lymphoma or B-Cell Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial of rituximab in young patients receiving chemotherapy for B-cell non-Hodgkin lymphoma or B-cell acute lymphoblastic leukemia h…
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CLINICAL_TRIALS trial_result · 2015-09-16Clinical Trial Update: Moxetumomab Pasudotox (CAT-8015, HA22) in Children With B-lineage Acute Lymphoblastic Leukemia and Minimal Residual Disease Prior to Allogeneic Hematopoietic Stem Cell Transplantation [Phase 2]
This is a Phase 2 clinical trial update reporting termination of a study evaluating moxetumomab pasudotox in pediatric B-lineage acute lymph…
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CLINICAL_TRIALS trial_result · 2015-09-09Clinical Trial Update: Clofarabine in Chinese Pediatric Patients With Refractory or Relapsed Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating clofarabine in Chinese pediatric patients with refractory or relapsed acute lymphoblastic leukemia has c…
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CLINICAL_TRIALS trial_result · 2015-09-07Clinical Trial Update: Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial assessing nilotinib in combination with standard chemotherapy for newly diagnosed acute lymphoblastic leukemia. Results have b…
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CLINICAL_TRIALS trial_result · 2015-08-25Clinical Trial Update: MK0457 in Patients With Leukemia (0457-003) [Phase 1]
Phase 1 trial update for MK-0457 (VX-680) in leukemia patients has completed; the study included chronic myeloid leukemia in blast crisis, a…
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CLINICAL_TRIALS trial_result · 2015-08-06Clinical Trial Update: Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 trial comparing dexamethasone vs prednisone in induction and methotrexate with/without leucovorin in maintenance for newly diagnosed…
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CLINICAL_TRIALS trial_result · 2015-08-06Clinical Trial Update: Combination Chemotherapy and Radiation Therapy in Treating Patients With Acute Lymphoblastic Leukemia That Has Relapsed in the CNS or Testes [NA]
This clinical trial update notes the completion and posting of results for a study evaluating combination chemotherapy and radiation therapy…
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: Efficacy and Safety Study of StemEx®, to Treat Subjects With High Risk Hematologic Malignancies, Following Myeloablative Therapy [Phase 2, Phase 3]
This update summarizes a Phase 2/Phase 3 study of StemEx for high-risk hematologic malignancies after myeloablative therapy, focusing on eff…
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CLINICAL_TRIALS trial_result · 2015-07-09Clinical Trial Update: Nilotinib With Chemotherapy for the Treatment of Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
This clinical trial update notes the termination of a Phase 1/2 study evaluating nilotinib in combination with chemotherapy for Philadelphia…
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CLINICAL_TRIALS trial_result · 2015-07-02Clinical Trial Update: Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery [Phase 1]
Phase 1 study sponsored by the National Cancer Institute evaluating dasatinib in patients with metastatic or unresectable solid tumors and l…
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CLINICAL_TRIALS trial_result · 2015-06-29Clinical Trial Update: Methotrexate, Vincristine, Pegylated L-Asparaginase and Dexamethasone (MOAD) in Acute Lymphoblastic Leukemia (ALL) Salvage [Phase 2]
Phase 2 results for the MOAD regimen (methotrexate, vincristine, pegylated L-asparaginase and dexamethasone) in salvage therapy for acute ly…
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CLINICAL_TRIALS trial_result · 2015-06-26Clinical Trial Update: Allogeneic Stem Cell Transplantation in Children and Adolescents With Acute Lymphoblastic Leukaemia [Phase 3]
Phase 3 clinical trial evaluating allogeneic stem cell transplantation in children and adolescents with acute lymphoblastic leukemia; the st…
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CLINICAL_TRIALS trial_result · 2015-06-26Clinical Trial Update: Study of Infusion of Blood Cells (Lymphocytes) to Stimulate the Immune System to Fight Leukemia/Lymphoma [Phase 2]
A Phase 2 trial evaluating infusion of blood cells (lymphocytes) to stimulate the immune system for fighting leukemia/lymphoma was terminate…
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancy [Phase 1]
Phase 1 clinical trial evaluating the safety, tolerability, and biological activity of oral clioquinol in patients with relapsed or refracto…
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CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: Study of Farnesyl Protein Transferase Inhibitor (FPTI) in Patients With Leukemia (Study P00701) [Phase 1, Phase 2]
Phase 1/2 trial of a Farnesyl Protein Transferase Inhibitor in leukemia and myelodysplastic syndromes has completed, sponsored by Merck Shar…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Phase I Study of OPB-51602 in Patients With Hematologic Malignancies [Phase 1]
Phase I trial results are reported for OPB-51602 in patients with hematologic malignancies including multiple myeloma, non-Hodgkin lymphoma,…
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CLINICAL_TRIALS trial_result · 2015-05-15Clinical Trial Update: Bortezomib, Vorinostat and Dexamethasone for Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase 2 trial evaluating bortezomib, vorinostat, and dexamethasone for relapsed/refractory acute lymphoblastic leukemia has been terminated …
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Chronic Graft-versus-host Disease (cGvHD) Prophylaxis With or Without ATG Prior to Stem Cell Transplantation (SCT) From HLA-identical Siblings in Patients With Acute Leukemia [Phase 3]
Phase 3 trial evaluating prophylaxis for chronic graft-versus-host disease using anti-thymocyte globulin (ATG) prior to stem cell transplant…
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Allogeneic Stem Cell Transplantation (SCT) With Treosulfan, VP-16 and Cyclophosphamid for Patients With Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase 2 clinical trial evaluating allogeneic stem cell transplantation using treosulfan, etoposide (VP-16), and cyclophosphamide for acute l…
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CLINICAL_TRIALS trial_result · 2015-05-08Clinical Trial Update: PROCEDYTE: Depocyte® Administration (Liposomal Cytarabine) as Prophylaxis of Neuromeningeal Infiltration in Acute Lymphoblastic Leukemia [Phase 3]
A Phase 3 trial of Depocyte (liposomal cytarabine) for prophylaxis of neuromeningeal infiltration in acute lymphoblastic leukemia has been t…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias [Phase 1]
Phase 1 study of TH-302 (evofosfamide), a hypoxia-activated prodrug, in patients with advanced leukemias has been completed, with evaluation…
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CLINICAL_TRIALS trial_result · 2015-04-30Clinical Trial Update: A Safety and Tolerability Study of Clofarabine, Etoposide, Cyclophosphamide, PEG-asparaginase, and Vincristine in Pediatric Acute Lymphoblastic Leukemia (ALL) [Phase 1]
Phase 1 safety and tolerability study of a multi-agent regimen (clofarabine, etoposide, cyclophosphamide, peg-asparaginase, and vincristine)…
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CLINICAL_TRIALS trial_result · 2015-04-28Clinical Trial Update: Sorafenib in Treating Patients With Refractory or Relapsed Acute Leukemia, Myelodysplastic Syndromes, or Blastic Phase Chronic Myelogenous Leukemia [Phase 1]
This Phase 1 trial update reports on the use of sorafenib in patients with refractory or relapsed acute leukemia, myelodysplastic syndromes,…