Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-02-01Clinical Trial Update: Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignancies [Phase 2]
Phase 2 trial of bortezomib plus vorinostat in younger patients with MLL-rearranged hematologic malignancies was terminated; results were po…
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: Safety & Efficacy of Atorvastatin for Prophylaxis of Acute Graft Versus Host Disease in Patients With Hematological Malignancies HLA- Donor Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating atorvastatin for prophylaxis of acute graft-versus-host disease in patients undergoing HLA-mon donor hematopoietic …
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CLINICAL_TRIALS trial_result · 2018-01-17Clinical Trial Update: A Study Of Inotuzumab Ozogamicin Versus Investigator's Choice Of Chemotherapy In Patients With Relapsed Or Refractory Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 trial comparing inotuzumab ozogamicin to investigator's choice chemotherapy in relapsed/refractory acute lymphoblastic leukemia has …
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CLINICAL_TRIALS trial_result · 2018-01-16Clinical Trial Update: Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT [Phase 2]
Phase 2 trial evaluating post-transplant cyclophosphamide as graft-versus-host disease prophylaxis after allogeneic hematopoietic stem cell …
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Rasburicase and Allopurinol in Treating Patients With Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating rasburicase and allopurinol in adults with hematologic malignancies; the study was terminated with results posted i…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: Total Marrow Irradiation for Refractory Acute Leukemia [Phase 1]
A Phase 1 trial evaluating total marrow irradiation for refractory acute leukemia has completed enrollment/status; the study included patien…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: AHN-12 Biodistribution in Advanced Leukemia [Phase 1]
A Phase 1 trial of the investigational agent AHN-12 focusing on biodistribution in advanced leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant [Phase 3]
Phase 3 trial update on graft-versus-host disease prophylaxis in patients with hematologic malignancies undergoing unrelated donor periphera…
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: An Open Label Phase II Pharmacokinetic and Pharmacodynamic Assessment of the Potential for QTc Prolongation Following First Induction Treatment With CPX-351 (Cytarabine:Daunorubicin) Liposome Injection in Acute Leukemias and MDS Patients [Phase 2]
This Phase 2 open-label pharmacokinetic/pharmacodynamic trial evaluated CPX-351 (cytarabine:daunorubicin liposome injection) for potential Q…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Donor Lymphocyte Infusion (DLI) for Relapsed (Post Transplant) Leukemia [NA]
The document reports the completion of a clinical trial evaluating donor lymphocyte infusion for relapsed leukemia after transplantation acr…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Yttrium Y 90 Anti-CD19 Antibody BU-12 in Patients With Advanced Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 trial of BU-12, a Yttrium-90 labeled anti-CD19 antibody, in advanced relapsed or refractory acute lymphoblastic leukemia or chronic …
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignancies [Phase 1]
A Phase 1 trial evaluated ABT-348 as a standalone therapy and in combination with azacitidine for advanced hematologic malignancies; the stu…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Sharing Our Strength: A Research Study for Bone Marrow/Stem Cell Transplant Survivors [NA]
The document reports a completed University of North Carolina clinical trial studying survivorship and psychological outcomes in bone marrow…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Lenalidomide in Acute Leukemias and Chronic Lymphocytic Leukemia. [Phase 1]
This update reports the completion of a Phase 1 trial evaluating lenalidomide in acute myeloid leukemia, acute lymphoblastic leukemia, and c…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Clinical Evaluation of Nelarabine (506U78)in Japanese Patients With Leukemia or Lymphoma [Phase 1]
Phase 1 clinical evaluation of nelarabine in Japanese patients with acute lymphoblastic leukemia and lymphoblastic lymphoma has been complet…
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CLINICAL_TRIALS trial_result · 2017-11-08Clinical Trial Update: T-cell Depleted Alternative Donor Transplantation [Phase 2]
Phase 2 clinical trial of T-cell depleted alternative donor transplantation for acute leukemias and related conditions was terminated with r…
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CLINICAL_TRIALS trial_result · 2017-10-12Clinical Trial Update: Intensified Conditioning Regimen With High-Dose-Etoposide for Allo-HSCT for Adult Acute Lymphoblastic Leukemia [Phase 2, Phase 3]
A Phase 2/3 trial evaluating intensified conditioning with high-dose etoposide for adults undergoing allogeneic hematopoietic stem cell tran…
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CLINICAL_TRIALS trial_result · 2017-10-02Clinical Trial Update: CAT-8015 in Children, Adolescents and Young Adults With Acute Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma [Phase 1]
Phase 1 trial update for CAT-8015 in children and young adults with acute lymphoblastic leukemia or non-Hodgkin's lymphoma; study completed …
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CLINICAL_TRIALS trial_result · 2017-09-27Clinical Trial Update: Study Evaluating the Safety and Efficacy of Astarabine in Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
A completed phase 1/2 trial evaluating safety and efficacy of Astarabine in acute myeloid leukemia and acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2017-09-15Clinical Trial Update: Pilot of Abatacept-based Immunosuppression for Prevention of Acute GvHD During Unrelated Donor HCT [Phase 2]
Phase 2 trial evaluating abatacept-based immunosuppression to prevent acute graft-versus-host disease during unrelated donor hematopoietic c…
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: Donor Peripheral Blood Stem Cell Transplant and Pretargeted Radioimmunotherapy in Treating Patients With High-Risk Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome [Phase 1]
Phase 1 trial evaluating donor peripheral blood stem cell transplantation in combination with pretargeted radioimmunotherapy for patients wi…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: PK Study of Oral and IV Clofarabine in High Risk Myelodysplasia+Acute Leukemias [Phase 1]
Phase 1 pharmacokinetic study of oral and intravenous clofarabine in high-risk myelodysplastic syndrome and acute leukemias; the trial has c…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Fludarabine Phosphate and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia That Has Responded to Treatment With Imatinib Mesylate, Dasatinib, or Nilotinib [Phase 2]
Phase 2 trial assessing fludarabine phosphate with total-body irradiation followed by donor peripheral blood stem cell transplant in adults …
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CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: Safety and Tolerability of HSC835 in Patients With Hematological Malignancies Undergoing Single Umbilical Cord Blood Transplant [Phase 2]
Phase 2 clinical trial update assessing safety and tolerability of HSC835 in patients with hematological malignancies undergoing single umbi…
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CLINICAL_TRIALS trial_result · 2017-08-09Clinical Trial Update: Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies [Phase 2]
This Phase 2 randomized trial comparing haplo cord blood transplantation versus double umbilical cord blood transplantation for hematologic …