Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Prophylactic and Therapeutic DLI-X for Leukemia Relapse After HCT [Phase 1]
Phase 1 clinical trial update on DLI-X as a prophylactic and therapeutic donor lymphocyte infusion to prevent or treat leukemia relapse afte…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study [NA]
Completed clinical trial evaluating a geriatric optimization plan to improve survival in older adults undergoing allogeneic hematopoietic ce…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest [NA]
A completed clinical trial evaluated two resuscitation sequences for managing simulated pediatric cardiac arrest.
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: The Role of Serum Cytokines IL_17 A and IL_10 in Disease Activity of Acute B Lymphoblastic Leukemia in South Egypt
A clinical trial is investigating the role of serum cytokines IL-17A and IL-10 in disease activity of B-cell acute lymphoblastic leukemia in…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: PK, PD, Safety and Immunogenicity of Spectrila in Adults With Acute B-cell Lymphoblastic Leukaemia [Phase 2]
Phase 2 study assessing PK, pharmacodynamics, safety and immunogenicity of Spectrila in adults with acute lymphoblastic leukemia (B-cell) ha…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant [Phase 1]
Phase 1 trial of intensity-modulated total marrow irradiation with fludarabine phosphate and melphalan for relapsed hematologic cancers unde…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO) [Phase 2]
A Phase 2 study evaluating a chemotherapy-free induction regimen for Philadelphia chromosome-positive acute lymphoblastic leukemia using ino…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia [Phase 1]
Phase 1 study to identify the highest dose of Revumenib (SNDX-5613) after hematopoietic stem cell transplant in children with acute lymphobl…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Safety and Feasibility of TMLI as Conditioning Regimen in Allogeneic Hematopoietic Stem-cell Transplantation [NA]
This clinical trial evaluated the safety and feasibility of Total Marrow and Lymphoid Irradiation (TMLI) as conditioning before allogeneic h…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Full-Course Immunotherapy Consolidation for Unfit or Fit B-ALL Who Decline Chemotherapy [Phase 2]
Phase 2 clinical trial update for consolidation immunotherapy in acute lymphoblastic leukemia patients who are unfit or decline chemotherapy…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Enzomenib (DSP-5336) for acute leukemias, including acute myeloid leukemia and acute lymphoblastic leu…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome [Phase 1]
A Phase 1 trial evaluating total marrow and lymphoid irradiation with fludarabine and melphalan before donor stem cell transplant for high-r…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]
Phase 2 trial evaluating HLA-mismatched unrelated donor hematopoietic cell transplantation with post-transplantation cyclophosphamide is act…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 study evaluating ruxolitinib in combination with chemotherapy in children with acute lymphoblastic leukemia has completed enrollme…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders [NA]
This update reports the completed status of a trial assessing bone marrow and kidney transplant for patients with chronic kidney disease and…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies [Phase 2]
Phase 2 clinical trial update evaluating TCRαβ-depleted progenitor cell graft with added memory T-cell donor lymphocyte infusion and selecti…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Efficacy and Toxicity of Blinatumomab in the French ATU for Adult BCP-ALL R/R, or With MRD+ (FRENCH-CYTO)
This completed French ATU study assessed the efficacy and safety of blinatumomab in adults with B-cell precursor acute lymphoblastic leukemi…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Low-Intensity Chemotherapy, Ponatinib and Blinatumomab in Treating Patients With Philadelphia Chromosome-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia [Phase 2]
This Phase 2 clinical trial evaluates low-intensity chemotherapy in combination with ponatinib and blinatumomab for Philadelphia chromosome-…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia [Phase 2]
Phase 2 clinical trial update describing a combination chemotherapy regimen for relapsed or refractory acute lymphoblastic leukemia, lymphob…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CAR-T Cells) for the Treatment of Relapsed/Refractory CD19+ Malignancies [Phase 1]
Phase 1 pilot study evaluating anti-CD19 CAR-T cells for relapsed/refractory CD19+ malignancies; the trial is currently recruiting at the Un…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Innovative Prosthetic Systems for Pediatric Limb Loss to Accommodate Growth [NA]
Clinical trial update on innovative prosthetic systems for children with limb deficiencies that can accommodate growth; the study is current…
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia [Phase 2]
This Phase 2 trial evaluating inotuzumab ozogamicin in children with MRD-positive CD22+ acute lymphoblastic leukemia was terminated.
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: A Study of 19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL) [Phase 1]
A Phase 1 study of 19-28z/IL-18 in adults with acute lymphoblastic leukemia is ongoing, including Philadelphia-negative and Philadelphia-pos…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: A Study to Evaluate the Tolerability, Safety, and Efficacy of an Anti-CD19 CAR-T Product in Patients With B-cell Lymphoproliferative Disorders [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a CD19-targeted CAR-T therapy for B-cell lymphoproliferative disorders has completed, assessing tolera…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Dose Escalation/Dose Expansion Study of PRGN-3007 UltraCAR-T Cells in Patients With Advanced Hematologic and Solid Tumor Malignancies [Phase 1]
Phase 1 dose-escalation and expansion study of PRGN-3007 UltraCAR-T cells in patients with advanced hematologic and solid tumors has complet…