Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Study of Palbociclib in MLL-rearranged Acute Leukemias [Phase 1, Phase 2]
A clinical trial investigating palbociclib in MLL-rearranged acute leukemias (AML and ALL) across Phase 1 and Phase 2 ongoing with currently…
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: ALL SCTped FORUM - Pharmacogenomic Study (add-on Study) [Phase 4]
Pharmacogenomic add-on study in Acute Lymphoblastic Leukemia is in Phase 4 and actively recruiting.
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CLINICAL_TRIALS trial_result · 2019-04-08Clinical Trial Update: CD19 hsCAR-T for Refractory/Relapsed CD19+ B-ALL Patients [Phase 2]
Phase 2 clinical trial update for CD19 hsCAR-T therapy in refractory/relapsed CD19+ B-ALL.
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CLINICAL_TRIALS trial_result · 2019-04-03Clinical Trial Update: Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma [Phase 2]
Phase 2 trial update on re-induction therapy for relapsed pediatric T-cell acute lymphoblastic leukemia or lymphoma; study terminated with p…
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CLINICAL_TRIALS trial_result · 2019-03-20Clinical Trial Update: Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD) [Phase 3]
A Phase 3 trial evaluating US-ATG-F to prevent chronic graft-versus-host disease in hematologic malignancy patients has completed with resul…
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CLINICAL_TRIALS trial_result · 2019-02-26Clinical Trial Update: Pilot Study Evaluating Safety & Efficacy of DCBT: NiCord® & UNM CBU to Patients With Hematological Malignancies [Phase 1, Phase 2]
A pilot Phase 1/2 study evaluating safety and efficacy of NiCord and UNM CBU in patients with various hematologic malignancies has completed…
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CLINICAL_TRIALS trial_result · 2019-02-19Clinical Trial Update: Erwinase for Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) (IND 104224) [Phase 1]
A Phase 1 trial of Erwinase for relapsed/refractory acute lymphoblastic leukemia, including patients with allergies to PEGylated or native E…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Chemotherapy With or Without Imatinib and/or Peripheral Stem Cell Transplant in Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating chemotherapy with or without imatinib and/or peripheral stem cell transplant in adults with acute lymphoblastic leu…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: SugarFACT - Sugar Requirements For African Children Trial [NA]
The SugarFACT trial evaluating sugar requirements for African children has been terminated, with conditions including hypoglycemia in non-di…
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: Bridging Study to Eliminate Presence of MRD for Acute Leukemia Before HCT [Phase 2]
Phase 2 bridging study evaluating elimination of minimal residual disease before hematopoietic cell transplantation in acute leukemia; study…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Propofol to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Anesthesia [NA]
This completed clinical trial evaluated whether propofol reduces postanesthetic emergence agitation in pediatric patients undergoing general…
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CLINICAL_TRIALS trial_result · 2019-01-25Clinical Trial Update: Clofarabine-cyclophosphamide as Salvage Therapy for Refractory and Relapsed Acute Lymphoblastic Leukemia (ALL) Adults [Phase 2]
A Phase 2 trial evaluating the combination of clofarabine and cyclophosphamide as salvage therapy for adults with refractory or relapsed acu…
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CLINICAL_TRIALS trial_result · 2019-01-25Clinical Trial Update: Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS [Phase 1]
Phase 1 clinical trial evaluating Yttrium-90 anti-CD45 monoclonal antibody BC8 followed by donor stem cell transplant in patients with high-…
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CLINICAL_TRIALS trial_result · 2019-01-24Clinical Trial Update: Red Cell Transfusion Goals in Patients With Acute Leukemias [Phase 1]
Phase 1 trial completed evaluating red blood cell transfusion goals in patients with acute leukemias (acute lymphoblastic leukemia, acute my…
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CLINICAL_TRIALS trial_result · 2019-01-18Clinical Trial Update: Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation [Phase 1]
Phase 1 trial evaluating inducible regulatory T cells (iTregs) in non-myeloablative sibling donor peripheral blood stem cell transplantation…
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CLINICAL_TRIALS trial_result · 2019-01-04Clinical Trial Update: Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies [Phase 2]
Phase 2 results from a study using donor umbilical cord blood stem cell transplants in patients with hematologic malignancies have been post…
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CLINICAL_TRIALS trial_result · 2018-12-10Clinical Trial Update: Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 3]
A Phase 3 trial evaluated whether adding lestaurtinib to standard chemotherapy improves outcomes in children with newly diagnosed acute lymp…
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CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: Anti-CD19 CAR-T Therapy Combine With HSCT to Treat MRD+ B-cell Malignancies [Phase 1, Phase 2]
A clinical trial update describes an anti-CD19 CAR-T therapy combined with hematopoietic stem cell transplantation for MRD-positive B-cell m…
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Nonmyeloablative Preparative Regimen Using Mylotarg for Patients With High Risk Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia (ALL), Chronic Myeloid Leukemia (CML) and Myelodysplastic Syndrome (MDS) [Phase 2, Phase 3]
A nonmyeloablative preparative regimen using Mylotarg (gemtuzumab ozogamicin) was studied in Phase 2/Phase 3 trials for high-risk acute myel…
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CLINICAL_TRIALS trial_result · 2018-10-23Clinical Trial Update: GIMEMA LAL 0496: High-dose Anthracycline in the Induction Regimen for the Treatment of Adult ALL. [Phase 2]
Phase 2 clinical trial evaluating high-dose anthracycline added to induction therapy for adults with acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2018-10-17Clinical Trial Update: G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumor [Phase 4]
A Phase 4 clinical trial evaluating G-CSF alone or in combination with GM-CSF for prevention and treatment of infection in children with mal…
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CLINICAL_TRIALS trial_result · 2018-10-09Clinical Trial Update: Bortezomib and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 study evaluating bortezomib with combination chemotherapy in adults with relapsed or refractory acute lymphoblastic leukemia; trial …
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CLINICAL_TRIALS trial_result · 2018-10-01Clinical Trial Update: A Dose-finding Study of the Bromodomain (Brd) Inhibitor OTX015/ Birabresib (MK-8628) in Hematologic Malignancies (MK-8628-001) [Phase 1]
Phase 1 dose-finding study of the bromodomain inhibitor birabresib (OTX015/MK-8628) in hematologic malignancies has completed with results p…
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CLINICAL_TRIALS trial_result · 2018-09-06Clinical Trial Update: Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 trial evaluating calaspargase pegol or pegaspargase with combination chemotherapy in younger patients with newly diagnosed high-risk…
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CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: HLA 10/10 Matched Unrelated Donor vs Haploidentical Allogenic Hematopoietic Stem Cell Transplantation [Phase 3]
Phase 3 trial comparing HLA 10/10 matched unrelated donor versus haploidentical allogeneic hematopoietic stem cell transplantation for acute…