Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-08-12Clinical Trial Update: Alemtuzumab and Clofarabine for Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
A clinical trial evaluating alemtuzumab and clofarabine for relapsed or refractory acute lymphoblastic leukemia was terminated; results were…
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CLINICAL_TRIALS trial_result · 2020-08-12Clinical Trial Update: IL-15 Super Agonist ALT-803 to Treat Relapse Of Hematologic Malignancy After Allogeneic SCT [Phase 1, Phase 2]
Clinical trial update on an IL-15 super agonist ALT-803 for relapse of hematologic malignancies after allogeneic stem cell transplant, compl…
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CLINICAL_TRIALS trial_result · 2020-08-11Clinical Trial Update: Pembrolizumab in Treating Minimal Residual Disease in Patients With Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial of pembrolizumab for acute lymphoblastic leukemia with minimal residual disease was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2020-07-24Clinical Trial Update: Adoptive TReg Cell for Suppression of aGVHD After UCB HSCT for Heme Malignancies [Phase 2]
A Phase 2 clinical trial investigating adoptive regulatory T cells to suppress acute graft-versus-host disease after umbilical cord blood st…
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CLINICAL_TRIALS trial_result · 2020-07-13Clinical Trial Update: Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL) [Phase 3]
Phase 3 pediatric trial comparing blinatumomab to standard chemotherapy in high-risk first-relapse B-precursor acute lymphoblastic leukemia …
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CLINICAL_TRIALS trial_result · 2020-07-08Clinical Trial Update: Evaluate the Neuroprotective Effect of Vitamin B6 and Vitamin B12 Against Vincristine Induced Neurotoxicity in Acute Lymphoblastic Leukaemia Patients [Phase 2, Phase 3]
A phase 2/3 trial evaluated whether vitamin B6 and vitamin B12 can protect against vincristine-induced neurotoxicity in patients with acute …
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CLINICAL_TRIALS trial_result · 2020-06-26Clinical Trial Update: P3 Study of Umbilical Cord Blood Cells Expanded With MPCs for Transplantation in Patients With Hematologic Malignancies [Phase 3]
Phase 3 trial of umbilical cord blood cells expanded with MPCs for transplantation in hematologic malignancies has completed.
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CLINICAL_TRIALS trial_result · 2020-06-23Clinical Trial Update: Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma [Phase 3]
A Phase 3 clinical trial update reports results of a risk-adapted chemotherapy approach for younger patients with newly diagnosed standard-r…
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CLINICAL_TRIALS trial_result · 2020-05-04Clinical Trial Update: Treosulfan-based Conditioning in Paediatric Patients With Haematological Malignancies [Phase 2]
Phase 2 trial update evaluating treosulfan-based conditioning in pediatric patients with hematological malignancies.
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CLINICAL_TRIALS trial_result · 2020-04-27Clinical Trial Update: Bioelectrical Impedance Measurement for Predicting Treatment Outcome in Patients With Newly Diagnosed Acute Leukemia [NA]
A completed clinical trial evaluating bioelectrical impedance measurements to predict treatment outcomes in newly diagnosed acute leukemia p…
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CLINICAL_TRIALS trial_result · 2020-04-21Clinical Trial Update: Donor-Derived Humoral Immunity, Hematopoietic Stem Cell Transplantation, TAR [NA]
Clinical trial update on donor-derived humoral immunity and hematopoietic stem cell transplantation completed with posted results in 2020.
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CLINICAL_TRIALS trial_result · 2020-04-15Clinical Trial Update: Thiopurine EnhAnced Maintenance Therapy [Phase 1, Phase 2]
Phase 1/2 trial evaluating thiopurine enhanced maintenance therapy in acute lymphoblastic leukemia and lymphoblastic lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2020-04-07Clinical Trial Update: Treatment of High Risk Adult Acute Lymphoblastic Leukemia [Phase 4]
Phase 4 clinical trial update for high-risk adult acute lymphoblastic leukemia sponsored by PETHEMA Foundation; study completed.
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CLINICAL_TRIALS trial_result · 2020-03-05Clinical Trial Update: Two Combination Chemotherapy Regimens in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 trial comparing two combination chemotherapy regimens in children with newly diagnosed acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2020-03-05Clinical Trial Update: Pethema LAL-RI/2008: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia [Phase 4]
Phase 4 trial update for standard risk acute lymphoblastic leukemia treated under the Pethema LAL-RI/2008 study.
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CLINICAL_TRIALS trial_result · 2020-02-26Clinical Trial Update: Study of ADCT-301 in Patients With Relapsed/Refractory CD25-positive Acute Myeloid Leukemia (AML) or CD25-positive Acute Lymphoblastic Leukemia (ALL) [Phase 1]
Phase 1 trial of ADCT-301 in relapsed/refractory CD25-positive AML or CD25-positive ALL was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-02-20Clinical Trial Update: AC220 for Children With Relapsed/Refractory ALL or AML [Phase 1]
Phase 1 clinical trial update for AC220 in children with relapsed/refractory acute lymphoblastic leukemia or acute myeloid leukemia; study c…
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CLINICAL_TRIALS trial_result · 2020-02-19Clinical Trial Update: Bortezomib With Chemotherapy for Relapsed Pediatric Acute Lymphoblastic Leukemia (ALL) [Phase 1, Phase 2]
Phase 1/2 trial update evaluating bortezomib in combination with chemotherapy for relapsed pediatric acute lymphoblastic leukemia; study com…
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CLINICAL_TRIALS trial_result · 2020-02-18Clinical Trial Update: INCB018424 in Patients With Advanced Hematologic Malignancies [Phase 2]
Phase 2 trial of INCB018424 (ruxolitinib) in patients with advanced hematologic malignancies. Results for diseases including AML, ALL, MDS, …
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: CART19 in Adult Patients With Minimal Residual Disease During Upfront Treatment for ALL [Phase 2]
Phase 2 trial update on CART19 therapy for adults with minimal residual disease during upfront treatment for acute lymphoblastic leukemia; s…
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CLINICAL_TRIALS trial_result · 2020-01-31Clinical Trial Update: Nivolumab and Dasatinib in Treating Patients With Relapsed or Refractory Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 clinical trial investigating nivolumab and dasatinib in relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic …
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CLINICAL_TRIALS trial_result · 2020-01-31Clinical Trial Update: Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating combination chemotherapy in newly diagnosed acute lymphoblastic leukemia in young patients.
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CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: Study of CD19 Specific Chimeric Antigen Receptor Positive T Cells (CAR-T) in ALL and NHL [Phase 1, Phase 2]
Clinical trial update on CD19 CAR-T therapy for acute lymphoblastic leukemia and non-Hodgkin lymphoma (Phase 1/Phase 2).
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CLINICAL_TRIALS trial_result · 2020-01-21Clinical Trial Update: T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts [Phase 2]
A Phase 2 clinical trial evaluating T cell depletion in recipients of HLA haploidentical related donor stem cell grafts for various hematolo…
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CLINICAL_TRIALS trial_result · 2020-01-14Clinical Trial Update: Addition of Gemcitabine to Pre Allo-HSCT Conditioning for Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating the addition of gemcitabine to pre-allo-HSCT conditioning in adults with acute lymphoblastic leukemia.