Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-06-08Clinical Trial Update: Unrelated Umbilical Cord Blood (UBC)Transplantation [NA]
Clinical trial update for unrelated umbilical cord blood transplantation; the study is completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-05-13Clinical Trial Update: A Phase I-II Open Label Non-Randomized Study Using TL32711 for Patients With Acute Myelogenous Leukemia, Myelodysplastic Syndrome and Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Phase I-II open-label trial of TL32711 in acute myeloid leukemia, myelodysplastic syndrome, and acute lymphoblastic leukemia; study terminat…
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CLINICAL_TRIALS trial_result · 2021-05-03Clinical Trial Update: Combination Chemotherapy and Ofatumumab in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma [Phase 2]
Phase 2 trial evaluating combination chemotherapy and Ofatumumab in adults with acute lymphoblastic leukemia or lymphoblastic lymphoma compl…
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CLINICAL_TRIALS trial_result · 2021-05-03Clinical Trial Update: Blinatumomab in High-risk B-cell Precursor Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating blinatumomab in adults with high-risk B-cell precursor acute lymphoblastic leukemia is ongoing (active, no…
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CLINICAL_TRIALS trial_result · 2021-04-13Clinical Trial Update: Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 study assessing the combination of chemotherapy with inotuzumab ozogamicin in patients with B-cell acute lymphoblastic leukemia, inc…
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CLINICAL_TRIALS trial_result · 2021-04-13Clinical Trial Update: Busulfan and Cyclophosphamide Followed By ALLO BMT [NA]
Clinical trial update for busulfan and cyclophosphamide followed by allogeneic stem cell transplant in acute leukemias; study is terminated …
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CLINICAL_TRIALS trial_result · 2021-04-12Clinical Trial Update: Inotuzumab Ozogamicin in Treating Patients With Relapsed or Refractory CD22 Positive Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating Inotuzumab Ozogamicin for relapsed or refractory CD22-positive acute lymphoblastic leukemia has been terminated wit…
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CLINICAL_TRIALS trial_result · 2021-03-19Clinical Trial Update: Anti-CD19 Chimeric Antigen Receptor (CAR)-Transduced T Cell Therapy for Patients With B Cell Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial update for an anti-CD19 CAR-T cell therapy in B cell malignancies has completed recruiting.
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CLINICAL_TRIALS trial_result · 2021-02-26Clinical Trial Update: Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating treosulfan, fludarabine phosphate, and total-body irradiation as conditioning before donor stem cell transplant in …
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Haploidentical Stem Cell Transplantation for Children With Therapy Resistant Leukemia [Phase 2]
Phase 2 clinical trial evaluating haploidentical stem cell transplantation for children with therapy-resistant leukemia (ALL and AML) has be…
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CLINICAL_TRIALS trial_result · 2021-02-04Clinical Trial Update: Vaccinating Children After Chemotherapy [Phase 4]
Phase 4 trial update on vaccinating children after chemotherapy for acute lymphoblastic leukemia; results posted.
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CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: Targeting CD19 and CD22 CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory Acute B Lymphocytic Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating CAR-T cells targeting CD19 and CD22 for relapsed or refractory acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor [Phase 2]
Phase 2 trial evaluating two doses of ATIR101 (T-lymphocyte enriched, host alloreactive T-cell depleted) in hematologic malignancy patients …
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Safety and Efficacy of Donor T-lymphocytes Depleted ex Vivo of Host Alloreactive T-cells (ATIR) in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor [Phase 2]
Phase 2 trial update on ATIR, donor T-lymphocytes depleted ex vivo of host alloreactive T-cells, in patients with hematologic malignancies p…
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Study to Evaluate Nilotinib in Adult Patients With Imatinib-resistant or Imatinib-intolerant Chronic Myelogenous Leukemia (CML), or Relapse/Refractory Ph+ Acute Lymphoblastic Leukemia (ALL) (Extension Study) [Phase 1, Phase 2]
Extension study evaluating nilotinib in adults with imatinib-resistant/intolerant CML or relapse/refractory Philadelphia-positive ALL; compl…
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CLINICAL_TRIALS trial_result · 2020-12-03Clinical Trial Update: Modified Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) Program for Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial update of Modified Hyper-CVAD regimen for acute lymphoblastic leukemia has completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-11-20Clinical Trial Update: Personalized Targeted Preparative Regimen Before T-depleted Allogeneic HSCT in Children With Chemoresistent Acute Leukemias [Phase 3]
Phase 3 trial evaluating a personalized preparative regimen prior to T-depleted allogeneic HSCT in children with chemoresistant acute leukem…
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CLINICAL_TRIALS trial_result · 2020-10-27Clinical Trial Update: A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL [Phase 1, Phase 2]
Phase 1/2 pilot trial of decitabine and vorinostat with chemotherapy for relapsed acute lymphoblastic leukemia (ALL) in children; study term…
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CLINICAL_TRIALS trial_result · 2020-10-12Clinical Trial Update: Donor Lymphocyte Infusion With Azacitidine to Prevent Hematologic Malignancy Relapse After Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial evaluating donor lymphocyte infusion with azacitidine to prevent relapse after stem cell transplantation.
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CLINICAL_TRIALS trial_result · 2020-10-08Clinical Trial Update: De Novo Adult Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia (ALL) Patients [Phase 2]
Phase 2 clinical trial update for de novo adult Philadelphia chromosome-positive acute lymphoblastic leukemia (ALL) patients.
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CLINICAL_TRIALS trial_result · 2020-09-21Clinical Trial Update: Transplantation of NiCord®, Umbilical Cord Blood-derived Ex Vivo Expanded Cells, in Patients With HM [Phase 1, Phase 2]
Phase 1/2 clinical trial update for NiCord (umbilical cord blood-derived ex vivo expanded cells) in hematological malignancies, including AL…
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CLINICAL_TRIALS trial_result · 2020-09-14Clinical Trial Update: Efficacy and Safety of the BiTE Antibody Blinatumomab in Chinese Adult Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (ALL) [Phase 3]
Phase 3 trial update on blinatumomab in Chinese adults with relapsed/refractory B-precursor acute lymphoblastic leukemia; results completed …
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CLINICAL_TRIALS trial_result · 2020-09-10Clinical Trial Update: Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases [Phase 2]
Phase 2 trial evaluating myeloablative umbilical cord blood transplantation in various hematological diseases has completed with results pos…
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CLINICAL_TRIALS trial_result · 2020-09-09Clinical Trial Update: ABT-751 With Chemotherapy for Relapsed Pediatric ALL [Phase 1, Phase 2]
Phase 1/Phase 2 trial of ABT-751 combined with chemotherapy for relapsed/recurrent pediatric acute lymphoblastic leukemia was terminated wit…
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CLINICAL_TRIALS trial_result · 2020-08-31Clinical Trial Update: Anti-CD19 White Blood Cells for Children and Young Adults With B Cell Leukemia or Lymphoma [Phase 1]
Phase 1 trial of anti-CD19 white blood cells in children and young adults with B-cell leukemia or lymphoma completed; results posted in 2020…