Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-11-14Clinical Trial Update: Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft Versus Host Disease (GVHD) Following Myeloablative Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-005) [Phase 3]
Phase 3 trial evaluating Efprezimod Alfa (CD24Fc, MK-7110) for prevention of acute graft-versus-host disease after myeloablative HSCT; study…
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CLINICAL_TRIALS trial_result · 2022-11-04Clinical Trial Update: Low-Intensity Chemotherapy and Blinatumomab in Treating Patients With Philadelphia Chromosome Negative Relapsed or Refractory Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial update on low-intensity chemotherapy combined with blinatumomab in Philadelphia chromosome–negative relapsed or refractory acu…
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CLINICAL_TRIALS trial_result · 2022-10-25Clinical Trial Update: Stem Cell Transplantation With NiCord® (Omidubicel) vs Standard UCB in Patients With Leukemia, Lymphoma, and MDS [Phase 3]
Phase 3 trial comparing NiCord (omidubicel) stem cell transplantation to standard umbilical cord blood in patients with hematologic malignan…
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CLINICAL_TRIALS trial_result · 2022-10-25Clinical Trial Update: Mitoxantrone and Clofarabine for Treatment of Recurrent NHL or Acute Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating mitoxantrone with clofarabine for recurrent non-Hodgkin lymphoma or acute leukemia has completed.
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CLINICAL_TRIALS trial_result · 2022-10-13Clinical Trial Update: Cladribine Combined With G-CSF and Cytarabine as a Salvage Treatment in R/R ALL [Phase 2, Phase 3]
A phase 2/3 clinical trial investigates cladribine with G-CSF and cytarabine as salvage therapy for relapsed/refractory acute lymphoblastic …
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CLINICAL_TRIALS trial_result · 2022-10-12Clinical Trial Update: "Geriatric Assessment Adapted" Therapy for Ph- ALL Elderly Patients [Phase 2]
Phase 2 clinical trial evaluating a geriatric assessment adapted therapy for elderly patients with Philadelphia-negative acute lymphoblastic…
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CLINICAL_TRIALS trial_result · 2022-10-07Clinical Trial Update: Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow [Phase 2]
Phase 2 trial update on specialized blood cell transplants for cancers of the blood and bone marrow; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-09-27Clinical Trial Update: Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial update for Hyper-CVAD with liposomal vincristine in acute lymphoblastic leukemia is completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-09-21Clinical Trial Update: Fludarabine / Total Body Irradiation Regimen for ALLO HCT in Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating a fludarabine and total body irradiation regimen as conditioning for allogeneic hematopoietic cell transpl…
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CLINICAL_TRIALS trial_result · 2022-09-10Clinical Trial Update: SC-PEG Asparaginase vs. Oncaspar in Pediatric Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma [Phase 2]
This Phase 2 trial compares SC-PEG Asparaginase to Oncaspar in pediatric acute lymphoblastic leukemia and lymphoblastic lymphoma, with resul…
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CLINICAL_TRIALS trial_result · 2022-09-02Clinical Trial Update: A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100) [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety and activity of pegylated recombinant human arginase (BCT-100) in pediatric cancers; study completed.
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CLINICAL_TRIALS trial_result · 2022-08-31Clinical Trial Update: Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies [Phase 1]
Phase 1 trial update of a genetically modified T-cell therapy targeting ROR1 in advanced malignancies, with terminated status and posted res…
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CLINICAL_TRIALS trial_result · 2022-08-05Clinical Trial Update: HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies [Phase 2]
Phase 2 clinical trial evaluating HLA-compatible related or unrelated donors with CD34+ enriched, T-cell depleted peripheral blood stem cell…
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CLINICAL_TRIALS trial_result · 2022-07-15Clinical Trial Update: Study of Efficacy and Safety of Reinfusion of Tisagenlecleucel in Pediatric and Young Adult Patients With Acute Lymphoblastic Leukemia (ALL) [Phase 2]
A Phase 2 trial evaluating reinfusion of tisagenlecleucel in pediatric and young adult patients with acute lymphoblastic leukemia has been t…
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CLINICAL_TRIALS trial_result · 2022-07-14Clinical Trial Update: Vyxeos(CPX-351) in Adults w R/R Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial of Vyxeos (CPX-351) in adults with relapsed or refractory acute lymphoblastic leukemia has completed and results were posted i…
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CLINICAL_TRIALS trial_result · 2022-07-13Clinical Trial Update: Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma [Phase 2]
Phase 2 trial evaluating a multi-agent regimen (etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin) for Acute Lymphoblastic L…
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CLINICAL_TRIALS trial_result · 2022-07-12Clinical Trial Update: Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant [Phase 1, Phase 2]
Clinical trial update for a phase 1/2 study evaluating gene-modified donor T-cells after TCR alpha beta–negative depleted stem cell transpla…
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CLINICAL_TRIALS trial_result · 2022-06-10Clinical Trial Update: A Clinical Study of SHP674 (Pegaspargase) in Participants With Newly Diagnosed, Untreated Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical study of SHP674 (Pegaspargase) in newly diagnosed, untreated acute lymphoblastic leukemia has completed with results posted…
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CLINICAL_TRIALS trial_result · 2022-05-27Clinical Trial Update: Phase II Study of Clofarabine in Pediatric Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase II study of clofarabine in pediatric acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2022-05-25Clinical Trial Update: Laboratory Treated T Cells in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, or Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating laboratory-treated T cells in relapsed or refractory B-cell malignancies and acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Sapanisertib in Treating Patients With Relapsed and/or Refractory Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating sapanisertib in adults with relapsed or refractory acute lymphoblastic leukemia; results were posted in Ma…
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Safety and Efficacy of ATIR101 as Adjunctive Treatment to Blood Stem Cell Transplantation From a Haploidentical Family Donor Compared to Post-transplant Cyclophosphamide in Patients With Blood Cancer [Phase 3]
Phase 3 trial updating safety and efficacy of ATIR101 as an adjunct to haploidentical stem cell transplantation versus post-transplant cyclo…
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: International Collaborative Treatment Protocol For Children And Adolescents With Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 international collaborative treatment protocol for children and adolescents with acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2022-05-18Clinical Trial Update: Comparative Study of BFC and BuCy Conditioning Regimen for Allo-PBSCT in Acute B-cell ALL [Phase 4]
Clinical trial comparing BFC versus BuCy conditioning for allogeneic stem cell transplant in acute B-lymphoblastic leukemia; Phase 4, status…
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CLINICAL_TRIALS trial_result · 2022-05-02Clinical Trial Update: Ruxolitinib Phosphate or Dasatinib With Chemotherapy in Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 trial evaluating ruxolitinib phosphate or dasatinib with chemotherapy in relapsed or refractory Philadelphia chromosome-like acute…