Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia [Phase 2]
The document describes a Phase 2 clinical trial evaluating a four-drug regimen (blinatumomab, methotrexate, cytarabine, and ponatinib) for P…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: CIK Cell Therapy for Relapsed or Refractory Acute B-Lymphoblastic Leukemia: Prognostic Impact on Patients With Early CAR-T Cell Dysfunction [NA]
Clinical trial update on cytokine-induced killer (CIK) cell therapy for relapsed or refractory B-cell acute lymphoblastic leukemia, assessin…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies [Phase 1, Phase 2]
A first-in-human study evaluating HLA partially to fully matched allogeneic, cryopreserved deceased donor bone marrow transplantation for va…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
A clinical trial update describing a study to learn more about the health of persons with Down syndrome after treatment for acute leukemia.
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 clinical trial evaluating imatinib mesylate in combination with chemotherapy for newly diagnosed Philadelphia chromosome-positive ac…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 1]
This clinical trial update describes a Phase 1 study of Orca-Q for patients with hematologic malignancies undergoing allogeneic stem cell tr…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT [NA]
Clinical trial update indicates ongoing recruitment for a study evaluating CD45RA-depleted peripheral stem cell addback to prevent viral or …
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution
A pharmacokinetic study is evaluating how crushing venetoclax tablets and dissolving them in solution affects drug exposure, to assess alter…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Inotuzumab Ozogamicin in Treating Patients With B-cell Acute Lymphocytic Leukemia With Positive Minimal Residual Disease [Phase 2]
Phase 2 clinical trial update evaluating Besponsa (Inotuzumab ozogamicin) for B-cell acute lymphoblastic leukemia with positive minimal resi…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant [Phase 2]
A Phase 2 clinical trial update evaluating busulfan, fludarabine phosphate, and post-transplant cyclophosphamide in patients with hematologi…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: The Effect of Mandala on Anxiety and Fear Levels in Children With Leukemia Before Intrathecal Chemotherapy Treatment [NA]
A clinical trial at Ege University is evaluating whether Mandala affects anxiety and fear levels in pediatric leukemia patients before intra…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Exploring the Effect of Calaspargase Pegol on the Coagulation System in Pediatric Acute Lymphoblastic Leukemia (ALL) Patients: Pilot Study
A Mayo Clinic-sponsored pilot clinical trial is evaluating how calaspargase pegol impacts the coagulation system in pediatric acute lymphobl…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma [Phase 2]
A Phase 2 clinical trial update from St. Jude Children's Research Hospital recruiting for therapy in newly diagnosed B-cell precursor acute …
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Weight Gain in Pediatric Leukemia Survivors [NA]
A clinical trial examining weight gain in pediatric leukemia survivors, currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Immune-targeted Combination With Chemotherapy for Acute Leukemia of Ambiguous Lineage [NA]
A clinical trial update notes a planned immune-targeted combination with chemotherapy for adult acute leukemia with ambiguous lineage (ALL/M…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Autologous CD22 CAR T Cells Following Commercial CD19 CAR T Cells in B Cell Malignancies [Phase 1]
Phase 1 trial evaluating autologous CD22-directed CAR T cells after prior commercial CD19-directed CAR T therapy in patients with B-cell mal…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: A 3-cohort Randomized Study Evaluating the Role of New Immunotherapeutic Agents and of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Frontline Therapy of Adults With Acute Lymphoblastic Leukemia [Phase 2, Phase 3]
This Clinical Trials entry describes a multicohort randomized study evaluating new immunotherapies and allogeneic hematopoietic stem cell tr…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Electronic Health Mindfulness-based Music Therapy Intervention for Patients Undergoing Allogeneic Stem Cell Transplantation [NA]
The document updates a clinical trial evaluating an electronic health mindfulness-based music therapy intervention for patients undergoing a…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy
A clinical trial update from Stanford examining outcomes in pediatric and young adult B-cell lymphoid malignancies after commercially availa…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Anti-CD19, Dual Co-stimulatory (4-1BB, CD3ζ) Chimeric Antigen Receptor T-cells in Patients With Relapsed/Refractory Aggressive Lymphoma or Acute Lymphoblastic Leukemia (ALL) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating CD19-directed CAR T-cells with dual co-stimulatory 4-1BB and CD3ζ domains in relapsed/refractory aggress…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: CD19 Chimeric Receptor Expressing T Lymphocytes In B-Cell Non Hodgkin's Lymphoma, ALL & CLL [Phase 1]
Phase 1 study evaluating CD19 CAR-T cells in B-cell non-Hodgkin lymphoma, chronic lymphocytic leukemia, and acute lymphoblastic leukemia; th…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Study to Determine Number of Patients Who Develop High Ammonia Levels After Receiving Recombinant Erwinia Asparaginase
This clinical trial update describes a study to determine how many patients develop elevated ammonia levels after receiving recombinant Erwi…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis [Phase 2]
Phase 2 clinical trial evaluating reduced-dose post-transplant cyclophosphamide as GVHD prophylaxis in HLA-mismatched unrelated donor periph…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: HIIT in Youth With Congenital Heart Disease (MedBIKE) [NA]
A clinical trial update for the MedBIKE study on high-intensity interval training in youth with congenital heart disease, currently recruiti…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Tafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage Leukemia [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating Tafasitamab (MOR00208) in pediatric patients with relapsed or refractory acute lymphoblastic leukem…