Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: CD5 Chimeric Antigen Receptor (CAR) T Cells in Subjects With Relapsed or Refractory T-cell Malignancies [Phase 1, Phase 2]
An update on an ongoing Phase 1/2 clinical trial evaluating CD5-targeted CAR T cells for relapsed or refractory T-cell malignancies, includi…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Clinical Trial of CD19 and CD22 CAR Sequential Therapy Versus Single CD19 CAR Bridging to HSCT for r/r B-ALL Patients [NA]
A recruiting clinical trial is evaluating sequential CD19 and CD22 CAR-T cell therapy versus a single CD19 CAR bridging to hematopoietic ste…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Phase I Study of Hyper-CVAD In Combination With Venetoclax In Pediatric Patients With Relapsed or Refractory Acute Leukemias That Are of the Lymphoid Lineage Including Bi-Phenotypic or Undifferentiated Leukemias [Phase 1]
A Phase I pediatric trial evaluating Hyper-CVAD in combination with venetoclax for relapsed or refractory acute leukemias of the lymphoid li…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Phase II Study of the Combination of Subcutaneous Blinatumomab and Olverembatinib in Patients With Philadelphia Chromosome (ph)-Positive and/or BCR::ABL1 Positive Acute Lymphoblastic Leukemia (ALL) [Phase 2]
Phase II clinical trial evaluating the combination of subcutaneous blinatumomab and olverembatinib for Philadelphia chromosome-positive and/…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Pediatric Normative Markerless Movement Analysis
A pediatric clinical trial evaluating normative markerless movement analysis in patients with acute lymphoblastic leukemia and adolescents i…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: CalPeg for Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) [Phase 1]
A Phase 1 clinical trial evaluating CalPeg for newly diagnosed acute lymphoblastic leukemia is currently recruiting. The study is sponsored …
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Ponatinib Plus Chemotherapy in Acute Lymphoblastic Leukemia Patients [Phase 2]
Phase 2 clinical trial evaluating ponatinib in combination with chemotherapy for acute lymphoblastic leukemia; currently not recruiting.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Phase II Study of the Combination of Ponatinib With Mini-hyper CVD Chemotherapy and Venetoclax in Patients With Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia [Phase 2]
Phase II trial evaluating the combination of ponatinib with mini-hyper CVD chemotherapy and venetoclax in relapsed or refractory T-cell acut…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant [Phase 1]
A Phase 1 clinical trial evaluating Revumenib for acute leukemia in patients after allogeneic stem cell transplant; the study is currently r…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: CiproPAL (Ciprofloxacin Prophylaxis in Acute Leukaemia) [NA]
This clinical trial update describes CiproPAL, a ciprofloxacin prophylaxis study in patients with acute lymphoblastic leukemia, which is cur…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Symptom Cluster Heterogeneity and Gut Microbiota Mechanisms in Childhood Cancer Survivors
A pediatric cancer survivor study focusing on symptom cluster heterogeneity and gut microbiota mechanisms is currently recruiting, including…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the combination of capivasertib, venetoclax, and low-intensity chemotherapy in adults with acute ly…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia [NA]
A University of Chicago-sponsored study tests whether text-message reminders can improve adherence to oral chemotherapy in adolescents and a…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Feasibility and Safety of Collecting and Combining Autologous Hematopoietic Stem Cells With Chimeric Antigen Receptor (CAR) T-Cell Therapy in Subjects With Relapsed/Refractory Hematological Malignancies [Phase 1]
A Phase 1 study evaluating feasibility and safety of collecting autologous hematopoietic stem cells and combining them with CAR T-cell thera…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: CD34+ Transplants for Leukemia and Lymphoma [Phase 2]
A Phase 2 clinical trial update on CD34+ transplants for acute myeloid leukemia and acute lymphoblastic leukemia, currently not recruiting.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma [Phase 4]
Phase 4 clinical trial update from St. Jude focusing on identifying information needed to guide treatment induction in newly diagnosed acute…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias [Phase 1, Phase 2]
Clinical trial update on an anti-CD19 CAR-T cell therapy being evaluated in Phase 1/Phase 2 for various leukemias and lymphoid cancers; recr…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Clinical Trial of CMD63 Chimeric Antigen Receptor T-cell (CAR T-cell) in Children With Acute Lymphoblastic Leukemia (ALL) [Phase 1]
Phase 1 clinical trial evaluating CMD63 CAR T-cell therapy in children with relapsed or refractory B-cell acute lymphoblastic leukemia, curr…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL [NA]
An ongoing clinical trial evaluating a tyrosine kinase inhibitor combined with chemotherapy and sequential CAR-T cell therapy in newly diagn…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies [Phase 2]
Phase 2 clinical trial update describing a donor stem cell transplant conditioning regimen with treosulfan, fludarabine, and total-body irra…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Expanded Access Program for OOS Obe-cel
Autolus Limited announced an Expanded Access Program for Obe-cel, its CAR-T therapy, to treat adults with acute lymphoblastic leukemia, incl…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood [Phase 2]
Phase 2 clinical trial evaluating co-transplant of an unmodified haplo-identical graft with cord blood; the study targets acute graft-versus…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Pharmacokinetics of Dexamethasone in Childhood ALL and Reduction in Bone Mineral Density
A pediatric pharmacokinetics study of dexamethasone in childhood acute lymphoblastic leukemia and assessment of dexamethasone-related bone m…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Phase 2 Study Assessing the Clinical Activity and Safety of Obecabtagene Autoleucel as a Consolidation in Patients With Newly Diagnosed High-risk B-cell Acute Lymphocytic Leukemia (ALL) [Phase 2]
Phase 2 study evaluating obecabtagene autoleucel as consolidation therapy in newly diagnosed high-risk B-cell acute lymphoblastic leukemia; …
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: A Study of BN104 in the Treatment of Acute Leukemia [Phase 1, Phase 2]
BN104 is being studied in Phase 1/2 trials for acute leukemia; the study is currently active but not recruiting.