Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Study of Obecabtagene Autoleucel in People With B-cell Acute Lymphoblastic Leukemia [Phase 2]
This document announces a Phase 2 clinical trial evaluating Obecabtagene Autoleucel for B-cell acute lymphoblastic leukemia, with recruitmen…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Hospital Based Continuous Patient Monitoring System [NA]
This entry reports a hospital-based continuous patient monitoring system trial that is not yet recruiting, covering trauma, post-appendectom…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial [Phase 3]
This entry details a Phase 3 extension study of Venetoclax for patients who completed prior Venetoclax trials. The study is currently active…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Study of Cell-free DNA in Children and Adolescents With Acute Lymphoblastic Leukemia
This clinical trial update describes a study evaluating cell-free DNA in children and adolescents with acute lymphoblastic leukemia. The stu…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: HEM-SURVIVE: Structuralized Follow-up for Childhood Hematological Malignancy Survivors
HEM-SURVIVE is a structured follow-up study for childhood survivors of hematologic malignancies; the trial is currently NOT_YET_RECRUITING a…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Assessment of Chimerism and Relapse Post Bone Marrow/Hematopoietic Cell Transplant (HCT) Using AlloHeme Test
A clinical trial update evaluating the AlloHeme test for assessing chimerism and detecting relapse after bone marrow/hematopoietic cell tran…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation [Phase 1, Phase 2]
A phase 1/2 trial evaluating Revumenib in relapsed/refractory leukemias including MLL/KMT2A rearrangements or NPM1 mutations; currently recr…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL) [Phase 1, Phase 2]
A Phase 1/2 clinical trial at the University of Chicago evaluating LP-118 with ponatinib, vincristine, and dexamethasone for relapsed/refrac…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Telematic Cognitive Training and Mindfulness in Pediatric Patients After CAR-T Cell Therapy, Single Hematopoietic Allogeneic Transplant or Chemotherapy [NA]
A pediatric study evaluating telematic cognitive training and mindfulness after CAR-T cell therapy, a single hematopoietic allogeneic transp…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation [Phase 2]
This Phase 2 clinical trial protocol investigates a post-transplant cyclophosphamide–based graft-versus-host disease prophylaxis approach in…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: International Study for Treatment of High Risk Childhood Relapsed ALL 2010 [Phase 2]
An international Phase 2 study is investigating treatment for high-risk childhood relapsed acute lymphoblastic leukemia and is currently rec…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma [Phase 2]
A Phase 2 clinical trial of Asparaginase Erwinia chrysanthemi in combination with chemotherapy for high-risk adults with newly diagnosed acu…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: TCR Reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B-ALL [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating an allogeneic CD19-targeting CAR-T cell therapy with TCR reservation and SPPL3 gene knockout (Po…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease
A University of Alberta trial is evaluating exercise MRI to assess cardiorespiratory fitness in children with heart disease and is currently…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders [Phase 2]
Phase 2 clinical trial evaluating cord blood transplant in children and young adults with blood cancers and select non-malignant disorders; …
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: HIIT in Pediatric Heart Transplant Recipients (MedBIKE™) [NA]
This clinical trial update describes a study evaluating high-intensity interval training (HIIT) using the MedBIKE device in pediatric heart …
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Venetoclax Basket Trial for High Risk Hematologic Malignancies [Phase 1]
A Phase 1 Venetoclax basket trial across multiple high-risk hematologic malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Study of the Efficacy of Moderate Sedation With Intra-NAsal Dexmedetomidine Monitored by EEG MOnitoring [NA]
Clinical trial update indicates a study of moderate sedation using intranasal dexmedetomidine monitored by EEG is currently recruiting in pe…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma [Phase 3]
Ongoing Phase 3 clinical trial evaluating levocarnitine to protect the liver from chemotherapy in children with acute lymphoblastic leukemia…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS) [Phase 2]
This is a Phase 2 clinical trial update evaluating strategies to reduce graft-versus-host disease in donor blood stem cell transplant patien…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases [NA]
This entry reports an ongoing clinical trial evaluating myeloablative preparative regimens for umbilical cord blood transplantation across s…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: UCD19 CAR T Therapy in Adults With B-ALL and MRD Positivity in CR1 [Phase 1]
This clinical trial update describes a Phase 1 study of UCD19 CAR T therapy in adults with B-cell acute lymphoblastic leukemia who are MRD-p…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: NUDT15/TPMT Multi-gene Guided 6-MP Dosing in Childhood ALL Maintenance Therapy [NA]
Clinical trial update on multi-gene guided dosing with 6-mercaptopurine for maintenance therapy in childhood acute lymphoblastic leukemia; c…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating CMV-MVA Triplex vaccination in HLA-matched related stem cell donors to prevent cytomegalovirus infection i…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Clinical Study on the Safety and Efficacy of BiTE-EV in Relapsed/Refractory Acute B-Cell Leukemia [EARLY_Phase 1]
An early-phase Phase 1 clinical study evaluating the safety and efficacy of BiTE-EV in relapsed/refractory acute lymphoblastic leukemia, cur…