Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-06-06Clinical Trial Update: CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL [Phase 1]
Phase 1 study of CD19/CD22 CAR-T cells in adults with relapsed or refractory acute lymphoblastic leukemia or B-cell lymphoma, currently recr…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant [Phase 1, Phase 2]
This clinical trial update examines using CD34+ malignant stem cell selection for patients receiving allogeneic stem cell transplants in Pha…
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Blinatumomab Maintenance After Allo-HSCT [Phase 2]
A Phase 2 clinical trial is evaluating blinatumomab as maintenance therapy after allogeneic hematopoietic stem cell transplantation in patie…
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Combination of an Anti-PD1 Antibody With Tisagenlecleucel Reinfusion in Children, Adolescents and Young Adults With Acute Lymphoblastic Leukemia After Loss of Persistence [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating reinfusion of tisagenlecleucel in combination with an anti-PD1 antibody for children, adolescents, and…
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: The Patient Cohort of the National Center for Precision Medicine in Leukemia
This clinical trial update describes the patient cohort for the National Center for Precision Medicine in Leukemia and notes that patient re…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: CD19 CAR-T Cells With CRS Suppression Technology for r/r CD19+ Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
This update describes a Phase 1/2 clinical trial of CD19 CAR-T cells with CRS suppression technology for relapsed/refractory CD19-positive a…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Determining the Mechanisms of Loss of CAR T Cell Persistence
A University College London trial is investigating the mechanisms behind loss of CAR T cell persistence in acute lymphoblastic leukemia and …
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Study Protocol: Study on Incidence and Risk Factors of Mold Infections in Children During Leukemia Treatment
This document describes a protocol for a study to determine the incidence of mold infections in children undergoing leukemia treatment and i…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With Fludarabine and Melphalan Reduced Intensity Conditioning in Adults With Acute Lymphoblastic Leukaemia (ALL) in Complete Remission. (ALL-RIC) [Phase 2]
Phase 2 clinical trial comparing reduced-dose total body irradiation with cyclophosphamide, fludarabine, and melphalan as reduced-intensity …
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Probiotic in Infant Growth, Allergy and Immunity Study [NA]
This clinical trial update indicates a probiotic study in healthy infants and infants with acute lymphoblastic leukemia is not yet recruitin…
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CLINICAL_TRIALS research · 2024-05-06Clinical Trial Update: The Effect of Kangaroo Care After Cardiac Surgery [NA]
An ongoing clinical trial sponsored by Istinye University is evaluating the effects of kangaroo care after cardiac surgery in infants with a…
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CLINICAL_TRIALS research · 2024-05-01Clinical Trial Update: Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research [EARLY_Phase 1]
A Phase 1 clinical trial update evaluating the safety and preliminary efficacy of metabolically armed CD19 CAR-T cells (Meta10-19) in relaps…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Care Pathway and Associated Costs of Patients Treated With CAR T-cells Based on SNDS Data
This study updates care pathways and costs for patients treated with CAR T-cell therapies using SNDS data.
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CLINICAL_TRIALS research · 2022-07-12Clinical Trial Update: Safety Study of Gene Modified Donor T-cells Following Partially Mismatched Stem Cell Transplant [Phase 1, Phase 2]
A Phase 1/2 safety study evaluating gene-modified donor T-cells after partially mismatched stem cell transplantation in patients with leukem…
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CLINICAL_TRIALS research · 2022-04-22Clinical Trial Update: Investigating the Effects of Hydroxyvitamin D3 on Multiple Sclerosis [Phase 4]
A Phase 4 clinical trial update investigates the effects of hydroxyvitamin D3 on multiple sclerosis and related conditions.
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CLINICAL_TRIALS research · 2020-11-23Clinical Trial Update: GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia [Phase 1, Phase 2]
Clinical trial exploring bendamustine as GVHD prophylaxis after transplantation in refractory leukemia, reported in Phase 1/Phase 2.
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CLINICAL_TRIALS research · 2019-09-06Clinical Trial Update: Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery
Clinical trial assessing electrophysiological biomarkers of chemotherapy-related cognitive impairment and recovery; study completed with pos…
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CLINICAL_TRIALS research · 2018-09-07Clinical Trial Update: WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular Electroporation [Phase 2]
Phase 2 clinical trial investigating WT1 DNA fusion gene vaccination with intramuscular injection and electroporation for haematological mal…
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CLINICAL_TRIALS research · 2018-07-30Clinical Trial Update: Tyrosine Kinase Inhibitors and Low Intensity Chemotherapy in Ph+ ALL
An update on a clinical trial evaluating tyrosine kinase inhibitors combined with low-intensity chemotherapy in Philadelphia chromosome-posi…
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CLINICAL_TRIALS research · 2018-07-24Clinical Trial Update: Rituximab+mVPDL for CD20(+) Adult Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating Rituximab in combination with mVPDL for CD20-positive precursor cell lymphoblastic leukemia-lymphoma in ad…
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CLINICAL_TRIALS research · 2018-07-13Clinical Trial Update: Creating a Decision Support System for the Corporate Management of Physical Therapy
A clinical trial update describing development of a decision support system to manage physical therapy for pediatric cancer patients, includ…
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CLINICAL_TRIALS research · 2018-07-06Clinical Trial Update: Evaluation of the Interest of a Specialist in Dermatology for Dermatopediatric Consultations
A clinical trial update evaluating the interest of a dermatology specialist for dermatopediatric consultations; sponsor is Central Hospital,…
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CLINICAL_TRIALS research · 2018-07-02Clinical Trial Update: Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer [NA]
Clinical trial update on caregiver-delivered massage therapy to improve quality of life in pediatric cancer patients; the study (NCT01053494…
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CLINICAL_TRIALS research · 2018-06-21Clinical Trial Update: Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL [Phase 2, Phase 3]
Clinical trial update for chidamide-based targeted therapy in adult T-cell lymphoblastic leukemia/lymphoma (T-LBL/ALL), spanning Phase 2 and…
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CLINICAL_TRIALS research · 2018-06-12Clinical Trial Update: Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult ETP-ALL [Phase 2, Phase 3]
A Phase 2/3 clinical trial update evaluating chidamide, an HDAC inhibitor, as targeted therapy for adult early T-cell precursor acute lympho…