Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Two Step Haplo With Radiation Conditioning [Phase 2]
Phase 2 clinical trial update describing two-step haploidentical transplantation with radiation conditioning for hematologic diseases, curre…
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL [Phase 1, Phase 2]
This clinical trial update concerns autologous CD19 CAR-T cell therapy with an inducible safety switch for relapsed/refractory acute lymphob…
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: Healthy Weight Intervention Families During ALL Treatment: NOURISH-ALL
NOURISH-ALL is a pediatric clinical trial examining a healthy weight intervention for families during treatment of childhood acute lymphobla…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors [Phase 1]
Phase 1 pediatric trial evaluating alpha/beta CD19+ depleted haploidentical transplantation in combination with Zoledronic acid (Zometa) for…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: 211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome [Phase 1, Phase 2]
This trial evaluates a targeted radiopharmaceutical (211At-BC8-B10) followed by an allogeneic donor stem cell transplant for relapsed or ref…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating naive T cell depletion to prevent chronic graft-versus-host disease in children and young adults receiving…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: CART22 Alone or in Combination With huCART19 for ALL [Phase 1]
A Phase 1 study at University of Pennsylvania evaluating CART22 alone or in combination with huCART19 for chemotherapy-resistant or refracto…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: A Bilingual Virtually-based Intervention (PEDALL) for the Prevention of Weight Gain in Childhood ALL Patients Considering Key Genetic and Sociodemographic Risk Factors [NA]
A clinical trial update for PEDALL, a bilingual virtual intervention to prevent weight gain in children with acute lymphoblastic leukemia, c…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Bio-CAR-T BS Study
A clinical trial update indicates the Bio-CAR-T BS study is currently recruiting for diffuse large B-cell lymphoma, primary mediastinal B-ce…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Efficacy of Targeted Drugs Combined With Chemotherapy in the Treatment of T-ALL [Phase 3]
A Phase 3 clinical trial evaluating targeted drugs combined with chemotherapy for T-cell acute lymphoblastic leukemia is currently recruitin…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies [EARLY_Phase 1]
An early-phase trial evaluating Darzalex Faspro (daratumumab and hyaluronidase-fihj) given before desensitization and allogeneic stem cell t…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Phase I Clinical Study of GNC-038 in Patients With Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia [Phase 1]
Phase I clinical trial update for GNC-038 in non-Hodgkin lymphoma and acute lymphoblastic leukemia; the study is currently not recruiting.
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Clinical Trial Using CAR- T Cells for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies [Phase 1]
A Phase 1 clinical trial update for CD19-directed CAR-T cell therapy in patients with refractory or relapsed B lymphoid malignancies is curr…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability
The PANDA Gym study is an ongoing clinical trial that uses automated assessment of neurodevelopment in infants at risk for motor disability …
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Study of Brexucabtagene Autoleucel Plus Dasatinib in Adults With Acute Lymphoblastic Leukemia [Phase 1]
A Phase 1 clinical trial evaluating the combination of brexucabtagene autoleucel (Tecartus) with dasatinib in adults with acute lymphoblasti…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Immunotherapy for High Risk/Relapsed CD19+ Acute Lymphoblastic Leukaemia, B-cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)/ Small Lymphocytic Lymphoma (SLL) Using CAR T-cells to Target CD19 [Phase 1]
A Phase 1 clinical trial update describing CD19-targeted CAR T-cell immunotherapy for high-risk or relapsed CD19+ acute lymphoblastic leukem…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Phase I Clinical Trial of CART Cell Therapy for Refractory/Relapsed Acute Lymphoblastic Leukemia in Children, Adolescents and Young Adults [Phase 1]
A Phase I clinical trial update describing CART cell therapy for refractory/relapsed acute lymphoblastic leukemia in children, adolescents, …
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Safety Study of CC312 in Adult Patients With Relapsed/Refractory CD19 Positive B-cell Hematologic Malignancies [Phase 1]
This clinical trial update describes a Phase 1 safety study of CC312 in adults with relapsed/refractory CD19-positive B-cell hematologic mal…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: BSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS [Phase 1, Phase 2]
Update on a Phase 1/2 trial of BSB-1001 in patients undergoing HLA-matched allogeneic hematopoietic stem cell transplantation for acute myel…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Multicenter Study on Rehabilitation Medical Data for Pediatric Big Brain Development
A multicenter clinical trial collecting rehabilitation data to study pediatric brain development and is currently recruiting, enrolling part…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies [Phase 1, Phase 2]
This clinical trial registration outlines a Phase 1/2 pediatric study of a multi-drug regimen (dasatinib, venetoclax, dexamethasone, cycloph…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies [Phase 1, Phase 2]
Ongoing Phase 1/Phase 2 clinical trial evaluating trametinib with dexamethasone and chemotherapy in children with relapsed or refractory acu…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: GT719 Injection for the Treatment of Recurrent/Refractory CD19 Positive Adult B-cell Malignancies [Phase 1, Phase 2]
GT719 Injection is being studied in a Phase 1/2 trial for recurrent or refractory CD19-positive adult B-cell malignancies, with recruitment …
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: A French Protocol for the Treatment of Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents [Phase 3]
Phase 3 French protocol for treating acute lymphoblastic leukemia in children and adolescents. The trial is currently active but not recruit…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies [Phase 1, Phase 2]
Clinical trial update for HEM-iSMART-C evaluating ruxolitinib, venetoclax, dexamethasone, cyclophosphamide, and cytarabine in pediatric pati…