Decompensated Heart Failure

• CLINICAL_TRIALS research · 2025-05-06
  Clinical Trial Update: The FOCUS-ADHF Registry

  This clinical trial registry entry notes that the FOCUS-ADHF Registry is currently recruiting to study acute heart failure with reduced ejec…

• CLINICAL_TRIALS research · 2025-04-08
  Clinical Trial Update: A Prospective, Observational, Single Centre Study to Assess the Feasibility of the Data Harvested by the Acorai Intracardiac Pressure Monitoring (ICPM) System in Predicting Prognosis in Patients Discharged From Hospital After Treatment for Acute Decompensated Heart Failure

  This clinical trial update describes a prospective, observational, single-centre study to evaluate whether data harvested from the Acorai in…

• CLINICAL_TRIALS trial_result · 2025-03-10
  Clinical Trial Update: EU Sites: Fluid Management of Acute Decompensated Heart Failure With Reprieve Decongestion Management System (FASTR-EU) [NA]

  A European trial update reports completion of the FASTR-EU study evaluating the Reprieve Decongestion Management System for fluid management…

• CLINICAL_TRIALS trial_result · 2025-01-28
  Clinical Trial Update: ExCR's Effects and Safety in Vulnerable ADHF Patients [NA]

  A clinical trial evaluating ExCR's effects and safety in vulnerable patients with acute decompensated heart failure is not yet recruiting, s…

• CLINICAL_TRIALS research · 2024-12-03
  Clinical Trial Update: Venous Ultrasound Guided Organ Decongestion in Patients Hospitalized with Acute Decompensated Heart Failure [NA]

  ClinicalTrials.gov reports an update on a trial testing venous ultrasound-guided organ decongestion in patients hospitalized with acute deco…

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• CLINICAL_TRIALS trial_result · 2024-11-14
  Clinical Trial Update: A Feasibility Study on Ultrafiltration and Blood Volume Measurements [NA]

  The feasibility trial NCT04241718 evaluating ultrafiltration and blood volume measurements for acute decompensated heart failure and fluid o…

• CLINICAL_TRIALS research · 2024-11-04
  Clinical Trial Update: Noninvasive Assessment of Pulmonary Fluid Levels by Remote Dielectric Sensing Technology to Improve Cardiac InsUfficieney During Ischemia-Reperfusion and Clinical Outcomes in MyocArdiaL Infarction [NA]

  This clinical trial evaluates a remote dielectric sensing device to noninvasively assess pulmonary fluid levels in patients with acute myoca…

• CLINICAL_TRIALS trial_result · 2024-10-28
  Clinical Trial Update: Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR) [Phase 4]

  Phase 4 trial ADVOR evaluating acetazolamide added to diuretic therapy in acute decompensated heart failure with volume overload; results ha…

• CLINICAL_TRIALS withdrawal · 2024-10-23
  Clinical Trial Update: Study on Early Intra-aortic Balloon Pump Placement in Acute Decompensated Heart Failure Complicated by Cardiogenic Shock [Phase 4]

  A Phase 4 trial evaluating early intra-aortic balloon pump placement in acute decompensated heart failure with cardiogenic shock has been te…

• CLINICAL_TRIALS research · 2024-10-22
  Clinical Trial Update: Combination Oral Acetazolamide and Intravenous Furosemide on Acute Decompensated Heart Failure Outcomes [Phase 4]

  Phase 4 clinical trial evaluating the combination of oral acetazolamide with intravenous furosemide for outcomes in acute decompensated hear…

• CLINICAL_TRIALS trial_result · 2024-10-21
  Clinical Trial Update: Comparative Effects of Methylprednisolone and Prednisolone on the Risk of Acute Decompensated Heart Failure - An Emulated Target Trial

  Completed emulated target trial evaluating the comparative risk of acute decompensated heart failure between methylprednisolone and predniso…

• CLINICAL_TRIALS research · 2024-09-19
  Clinical Trial Update: The Association Between Visual Echocardiographic Scoring System and Clinical Outcomes in Patient With Acute Decompensated Heart Failure

  A recruiting clinical trial is investigating the association between a visual echocardiographic scoring system and clinical outcomes in pati…

• CLINICAL_TRIALS trial_result · 2024-09-19
  Clinical Trial Update: Evaluation of the Diagnostic Value of the TPD System in Determining ADHF Causing Acute Dyspnea [NA]

  Clinical trial update notes termination of a study evaluating the diagnostic value of the TPD System for determining acute decompensated hea…

• CLINICAL_TRIALS trial_result · 2024-08-20
  Clinical Trial Update: Nitroglycerin vs. Furosemide Using Lung Ultrasound Pilot Trial [Phase 2]

  Phase 2 pilot trial comparing nitroglycerin to furosemide using lung ultrasound in acute heart failure; the study was terminated and results…

• CLINICAL_TRIALS other · 2024-08-05
  Clinical Trial Update: Acetazolamide Versus Dapagliflozin in Acute Decompensated Heart Failure Patients [Phase 3]

  Phase 3 clinical trial comparing acetazolamide to dapagliflozin in patients with acute decompensated heart failure is currently recruiting.

• CLINICAL_TRIALS research · 2024-07-24
  Clinical Trial Update: Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload [Phase 4]

  Phase 4 clinical trial update on the efficacy and safety of combination diuretic therapy in patients with acute decompensated heart failure …

• CLINICAL_TRIALS research · 2024-06-20
  Clinical Trial Update: Adherence to Medication in Patients With Acute Decompensated Heart Failure

  An ongoing clinical trial is recruiting to study adherence to medication in patients with Acute Decompensated Heart Failure, led by Universi…

• CLINICAL_TRIALS research · 2024-06-17
  Clinical Trial Update: Feasibility Study to Support Cardiorenal Function in Acute Decompensated Heart Failure With Diuretic Resistance [NA]

  Puzzle Medical Devices is conducting a feasibility study to support cardiorenal function in acute decompensated heart failure with diuretic …

• CLINICAL_TRIALS trial_result · 2024-05-08
  Clinical Trial Update: Monocyte Phenotypic Changes in Heart Failure

  Completed clinical study examining monocyte phenotypic changes in patients with heart failure, including those with decompensated heart fail…

• CLINICAL_TRIALS research · 2024-05-06
  Clinical Trial Update: Naturally Controlled Decongestion Using Renal Independent System in ADHF Patients, a European Registry [NA]

  This entry describes a European registry trial evaluating a Renal Independent Decongestion System for acute decompensated heart failure, wit…

• CLINICAL_TRIALS trial_result · 2023-12-06
  Clinical Trial Update: The Hemodynamic Effects of SGLT2i in Acute Decompensated Heart Failure [Phase 4]

  A Phase 4 trial assessed the hemodynamic effects of SGLT2 inhibitors in acute decompensated heart failure and the study was terminated with …

• CLINICAL_TRIALS trial_result · 2023-09-11
  Clinical Trial Update: Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency [Phase 3]

  Phase 3 clinical trial update assessing safety and tolerability of intravenous tonapofylline in subjects with acute decompensated heart fail…

• CLINICAL_TRIALS trial_result · 2023-08-22
  Clinical Trial Update: Asses the Anti-inflammatory Effects of Short Term Copaxone Therapy on Patients the Acute Decompensated Heart Failure [Phase 2]

  Phase 2 clinical trial update evaluating short-term Copaxone therapy for anti-inflammatory effects in acute decompensated heart failure.

• CLINICAL_TRIALS trial_result · 2023-05-24
  Clinical Trial Update: The Clinical Study of the Safety and Efficacy of Istaroxime in Treatment of Acute Decompensated Heart Failure [Phase 2]

  Phase 2 clinical trial evaluating safety and efficacy of istaroxime in acute decompensated heart failure has completed with results posted.

• CLINICAL_TRIALS withdrawal · 2023-05-03
  Clinical Trial Update: Combination Diuretic Therapy for Acute Decompensated Heart Failure [Phase 4]

  A Phase 4 clinical trial evaluating combination diuretic therapy for acute decompensated heart failure has been withdrawn.