Decompensated Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: Comparison of the Effectiveness of Different Diuretic Therapies in the Management of Acute Heart Failure [NA]
A completed clinical trial comparing the effectiveness of different diuretic therapies in the management of acute decompensated heart failur…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: DORAYA-HF OUS Assessment of the Doraya Catheter for the Treatment of ADHF Patients With Insufficient Response to Diuretics [NA]
The DORAYA-HF trial evaluating the Doraya Catheter for acute decompensated heart failure with insufficient diuretic response has completed.
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Optimizing Treatments for Heart Failure During Hospitalization
This completed clinical trial conducted at Central Hospital in Nancy, France evaluated strategies to optimize treatment for patients hospita…
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Interest of Levosimendan in Reducing Weaning Failures of ExtraCorporeal Life Support - ECLS [Phase 3]
Phase 3 trial evaluating levosimendan to reduce weaning failures from extracorporeal life support in acute decompensated heart failure has b…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: A Study of Ultra High Dose Diuretics to Treat Heart Failure [Phase 2]
A Phase 2 clinical trial evaluating ultra-high-dose diuretics for heart failure with decompensation has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Effects of In-Hospital Cardiac Rehabilitation and Manual Lymphatic Drainage in Acute Decompensated Heart Failure [NA]
The clinical trial evaluating in-hospital cardiac rehabilitation and manual lymphatic drainage for acute decompensated heart failure has com…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Levosimendan in Acute Decompensated Heart Failure [Phase 2, Phase 3]
This document reports on a phase 2/3 clinical trial evaluating levosimendan for acute decompensated heart failure, with the trial currently …
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: SVC Occlusion in Subjects With Acute Decompensated Heart Failure [NA]
Clinical trial update reports completion of a study evaluating superior vena cava occlusion in subjects with acute decompensated heart failu…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Clinical Outcomes of Levosimendan Versus Dobutamine Versus Milrinone in Cases With Acute Decompensated Heart Failure With Impaired Renal Function
Completed clinical trial comparing levosimendan, dobutamine, and milrinone for acute decompensated heart failure with impaired renal functio…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve Decongestion Management System (DMS) [NA]
The clinical trial evaluating the Reprieve Decongestion Management System for fluid management in acute decompensated heart failure has comp…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Motivational Enhancement - Acute Decompensated Heart Failure and OSA [NA]
A completed Cleveland Clinic study evaluated motivational enhancement to improve PAP adherence in patients with acute decompensated heart fa…
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: Comparative Assessment of Efficacy & Safety of Sacubitril/Valsartan Versus Ramipril in Patients With Renal Dysfunction Hospitalized With Acute Decompensated Heart Failure [Phase 2, Phase 3]
A Phase 2/3 trial comparing sacubitril/valsartan to ramipril in patients with renal dysfunction hospitalized for acute decompensated heart f…
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: SURPASS Impella 5.5 Study
Clinical trial update for the SURPASS Impella 5.5 study sponsored by Abiomed; the study addresses cardiogenic shock and acute decompensated …
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: EU Sites: Fluid Management of Acute Decompensated Heart Failure With Reprieve Decongestion Management System (FASTR-EU) [NA]
A European trial update reports completion of the FASTR-EU study evaluating the Reprieve Decongestion Management System for fluid management…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: ExCR's Effects and Safety in Vulnerable ADHF Patients [NA]
A clinical trial evaluating ExCR's effects and safety in vulnerable patients with acute decompensated heart failure is not yet recruiting, s…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: A Feasibility Study on Ultrafiltration and Blood Volume Measurements [NA]
The feasibility trial NCT04241718 evaluating ultrafiltration and blood volume measurements for acute decompensated heart failure and fluid o…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR) [Phase 4]
Phase 4 trial ADVOR evaluating acetazolamide added to diuretic therapy in acute decompensated heart failure with volume overload; results ha…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Comparative Effects of Methylprednisolone and Prednisolone on the Risk of Acute Decompensated Heart Failure - An Emulated Target Trial
Completed emulated target trial evaluating the comparative risk of acute decompensated heart failure between methylprednisolone and predniso…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Evaluation of the Diagnostic Value of the TPD System in Determining ADHF Causing Acute Dyspnea [NA]
Clinical trial update notes termination of a study evaluating the diagnostic value of the TPD System for determining acute decompensated hea…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Nitroglycerin vs. Furosemide Using Lung Ultrasound Pilot Trial [Phase 2]
Phase 2 pilot trial comparing nitroglycerin to furosemide using lung ultrasound in acute heart failure; the study was terminated and results…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Monocyte Phenotypic Changes in Heart Failure
Completed clinical study examining monocyte phenotypic changes in patients with heart failure, including those with decompensated heart fail…
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: The Hemodynamic Effects of SGLT2i in Acute Decompensated Heart Failure [Phase 4]
A Phase 4 trial assessed the hemodynamic effects of SGLT2 inhibitors in acute decompensated heart failure and the study was terminated with …
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CLINICAL_TRIALS trial_result · 2023-09-11Clinical Trial Update: Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency [Phase 3]
Phase 3 clinical trial update assessing safety and tolerability of intravenous tonapofylline in subjects with acute decompensated heart fail…
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CLINICAL_TRIALS trial_result · 2023-08-22Clinical Trial Update: Asses the Anti-inflammatory Effects of Short Term Copaxone Therapy on Patients the Acute Decompensated Heart Failure [Phase 2]
Phase 2 clinical trial update evaluating short-term Copaxone therapy for anti-inflammatory effects in acute decompensated heart failure.
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: The Clinical Study of the Safety and Efficacy of Istaroxime in Treatment of Acute Decompensated Heart Failure [Phase 2]
Phase 2 clinical trial evaluating safety and efficacy of istaroxime in acute decompensated heart failure has completed with results posted.