Decompensated Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258) [Phase 3]
Phase 3 trial update for the FASTR-II study evaluating fluid management with the Reprieve System in acute decompensated heart failure; trial…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Salivary Extracellular Vesicle Associated lncRNAs in Heart Failure (SEAL-HF)
The SEAL-HF trial (NCT06169540) at Massachusetts General Hospital is evaluating salivary extracellular vesicle associated lncRNAs as biomark…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Circulating RNAs in Acute Congestive Heart Failure
Massachusetts General Hospital is conducting a study on circulating RNAs as potential biomarkers in patients with acute decompensated heart …
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Comparative Efficacy and Safety of Acetazolamide Versus Metolazone as an Adjunct to Standard Therapy in Patients With Acute Decompensated Heart Failure [NA]
This trial compares acetazolamide to metolazone as an adjunct to standard therapy in patients with acute decompensated heart failure; recrui…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: SVC Occlusion in Subjects With Acute Decompensated Heart Failure [NA]
Clinical trial update reports completion of a study evaluating superior vena cava occlusion in subjects with acute decompensated heart failu…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Clinical Outcomes of Levosimendan Versus Dobutamine Versus Milrinone in Cases With Acute Decompensated Heart Failure With Impaired Renal Function
Completed clinical trial comparing levosimendan, dobutamine, and milrinone for acute decompensated heart failure with impaired renal functio…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Bioimpedance Integration for Optimized Fluid Management in Decompensated Heart Failure [NA]
This document provides a clinical trial update about a study evaluating bioimpedance integration for optimized fluid management in decompens…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: BIO|CONCEPT.BIOMONITOR-HF Collect Clinical Data From Heart Failure Patients Using BIOMONITOR Devices With a Study Specific Research Software [NA]
Biotronik's BIOMONITOR-HF study is recruiting to collect clinical data from heart failure and arrhythmia patients using BIOMONITOR devices a…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: The Effect of Dapagliflozin on Patients With Cardiomyopathy [Phase 4]
Phase 4 clinical trial update evaluating dapagliflozin in patients with cardiomyopathy, including acute decompensated heart failure. The stu…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: EACH-ADHF: Early Comprehensive Rehabilitation in Patients With ADHF [NA]
The EACH-ADHF study is currently recruiting patients with acute decompensated heart failure to evaluate early comprehensive rehabilitation.
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure
A completed trial evaluating whether UCHL1 can serve as a diagnostic biomarker for acute decompensated heart failure.
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure
A study at UConn Health is examining circulating biomarkers that accompany the progression from compensated hypertrophy to heart failure, an…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Loop Diuretic Therapy in Acutely Decompensated Heart Failure
A clinical trial sponsored by the University of Siena is evaluating loop diuretic therapy in patients with acute decompensated heart failure…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve Decongestion Management System (DMS) [NA]
The clinical trial evaluating the Reprieve Decongestion Management System for fluid management in acute decompensated heart failure has comp…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Using an Intervention Adapted to the Health Literacy Level to Improve Adherence to Medical Recommendations [NA]
A clinical trial is evaluating an intervention tailored to patients' health literacy to improve adherence to medical recommendations in peop…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Motivational Enhancement - Acute Decompensated Heart Failure and OSA [NA]
A completed Cleveland Clinic study evaluated motivational enhancement to improve PAP adherence in patients with acute decompensated heart fa…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Bedside Ultrasound-guided Volume Management and Discharge Timing for Patients With Heart Failure During Hospitalization: A Randomized Controlled Trial [NA]
Clinical trial update for a randomized controlled trial on bedside ultrasound-guided volume management and discharge timing in hospitalized …
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: Comparative Assessment of Efficacy & Safety of Sacubitril/Valsartan Versus Ramipril in Patients With Renal Dysfunction Hospitalized With Acute Decompensated Heart Failure [Phase 2, Phase 3]
A Phase 2/3 trial comparing sacubitril/valsartan to ramipril in patients with renal dysfunction hospitalized for acute decompensated heart f…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Pharmacokinetics of Bisoprolol and SGLT2i in Acutely Decompensated Heart Failure
This clinical trial update describes the pharmacokinetics of bisoprolol and SGLT2 inhibitors in patients with acutely decompensated heart fa…
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FDA approval · 2025-06-05FDA Approved: MILRINONE LACTATE — Supplemental Application (Shandong New Time Pharmaceutical Co., Ltd.)
FDA approved a supplemental ANDA for milrinone lactate from Shandong New Time Pharmaceutical Co., Ltd., authorizing the generic product for …
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CLINICAL_TRIALS withdrawal · 2025-05-31Clinical Trial Update: HEMolysis in a Percutaneous Axial Flow LVAD, Effects of Pentoxifylline in a Randomized Controlled Trial [Phase 4]
A Phase 4 randomized trial evaluating pentoxifylline for hemolysis in patients with a percutaneous axial-flow left ventricular assist device…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Low Level Tragus Stimulation in Acute Decompensated Heart Failure [NA]
A clinical trial update indicating that recruitment is ongoing for a study of low level tragus stimulation in acute decompensated heart fail…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Safety and Performance Evaluation of the Nephronyx System for the Treatment of Patients With ADHF [NA]
Nephronyx LTD reports a clinical trial evaluating the Nephronyx System for safety and performance in acute decompensated heart failure, with…
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: SURPASS Impella 5.5 Study
Clinical trial update for the SURPASS Impella 5.5 study sponsored by Abiomed; the study addresses cardiogenic shock and acute decompensated …
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Change in Stroke Volume Index After Diuresis for Patients With Decompensated Heart Failure
An ongoing clinical trial evaluates changes in stroke volume index after diuresis for patients with acute decompensated heart failure. The t…