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CLINICAL_TRIALS research · 2025-12-02

Clinical Trial Update: The Efficacy and Safety of Neoadjuvant Therapy With Iparomlimab and Tuvonralimab in Locally Advanced MSI-H/dMMR Colorectal Cancer: An Prospective, Single-Arm Study (Neo-IT) [Phase 2]

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Summary

Phase 2 neoadjuvant trial evaluating the immune therapies iparomlimab and tuvonralimab in locally advanced dMMR/MSI-H rectal adenocarcinoma; the study is curren…

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Diseases / indications

Drugs mentioned

  • Tuvonralimab (tuvonralimab)
  • iparomlimab

Snippet

Sponsor: Sir Run Run Shaw Hospital | Conditions: dMMR/MSI-H-type Rectal Adenocarcinoma | Phase 2 | Status: ACTIVE_NOT_RECRUITING