Xerostomia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: SaliPen Human Factors Study for OTC Labeling [NA]
Completed human factors study for over-the-counter labeling of SaliPen for xerostomia; results posted.
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: Aloe Vera Versus Thyme Honey Mouthwash in Management of Xerostomia in Type 2 Diabetics [Phase 3]
Phase 3 clinical trial comparing Aloe Vera versus Thyme Honey mouthwash for management of xerostomia in type 2 diabetics.
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CLINICAL_TRIALS trial_result · 2023-08-09Clinical Trial Update: the Effect of Mixture of Natural Products As Salivary Substitutes in Treatment Of Xerostomia [Phase 3]
Phase 3 clinical trial evaluating a mixture of natural products as salivary substitutes for xerostomia in Sjogren's syndrome; study complete…
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CLINICAL_TRIALS trial_result · 2023-07-24Clinical Trial Update: Effects of an External Oral Irrigation Device on Patients With Dry Mouth [NA]
Completed clinical trial evaluating an external oral irrigation device for xerostomia; results posted in 2023.
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FDA approval · 2023-04-06FDA Approved: CEVIMELINE HYDROCHLORIDE — Original Application (Advagen Pharma Ltd)
FDA approves Advagen Pharma Ltd's cevimeline hydrochloride as an original application. It is indicated for the treatment of xerostomia in Sj…
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CLINICAL_TRIALS trial_result · 2022-12-28Clinical Trial Update: Mesenchymal Stemcells for Radiation Induced Xerostomia [Phase 2]
Phase 2 trial of mesenchymal stem cells for radiation-induced xerostomia completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: Xerostomia in Patients With a Life-limiting Condition or Frailty [Phase 3]
Phase 3 clinical trial update investigating xerostomia (dry mouth) in patients with a life-limiting condition or frailty.
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CLINICAL_TRIALS research · 2022-07-05Clinical Trial Update: Photobiomodulation on the Salivary Glands of Patients With Xerostomia Induced by the Use of Benzodiazepines [Phase 1, Phase 2]
Phase 1/2 trial investigating photobiomodulation for xerostomia induced by benzodiazepine use.
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CLINICAL_TRIALS trial_result · 2022-04-22Clinical Trial Update: Comparison of Gum® HydralTM Moisturizing Gel and Biotene® Oral Gel in Dry Mouth Sensation Reduction [Phase 3]
Phase 3 trial comparing Gum Hydral Moisturizing Gel to Biotene Oral Gel for reduction of dry mouth sensation (xerostomia) is completed.
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CLINICAL_TRIALS trial_result · 2022-02-24Clinical Trial Update: Clinical Evaluation of Oral Rinse for Xerostomia [NA]
Clinical trial evaluation of an oral rinse for xerostomia has completed; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2021-06-04Clinical Trial Update: Exploratory Study for Dry Mouth in Patients With Sjögren's Syndrome [Phase 2]
Phase 2 exploratory trial studying dry mouth in Sjögren's syndrome; completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-11-20Clinical Trial Update: Evaluation of the Efficacy of 3M Dry Mouth Moisturizing Spray [NA]
A completed clinical trial evaluated the efficacy of 3M Dry Mouth Moisturizing Spray for xerostomia and posted results.
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FDA approval · 2020-09-21FDA Approved: PILOCARPINE HYDROCHLORIDE — Original Application (Amneal Pharmaceuticals NY LLC)
FDA approves Amneal Pharmaceuticals NY LLC's pilocarpine hydrochloride under an original generic application.
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: An Evaluation of the Impact of a Single Dose of P-552 on Oral Mucosal Wetness [Phase 1, Phase 2]
Phase 1/2 trial evaluating a single dose of P-552 for oral mucosal wetness in xerostomia and Sjogren's syndrome. Study status completed.
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients [NA]
The document reports results from a completed clinical trial evaluating the efficacy of an oral moisturizing jelly in improving oral health …
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CLINICAL_TRIALS trial_result · 2018-12-11Clinical Trial Update: NeutraSal Treatment for Xerostomia in OSAS Patients Using CPAP Therapy [NA]
Completed clinical trial evaluating NeutraSal for xerostomia in OSAS patients on CPAP; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-11-02Clinical Trial Update: Dexamethasone Irrigation of the Parotid Glands in Primary Sjögren's Syndrome Subjects [Phase 2]
Phase 2 trial evaluating dexamethasone irrigation of parotid glands in Sjögren's syndrome with xerostomia; study terminated with results pos…
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CLINICAL_TRIALS trial_result · 2018-10-11Clinical Trial Update: Photobiomodulation in Salivary Production of Patients With Xerostomy [Phase 2]
Phase 2 clinical trial update exploring photobiomodulation to improve salivary production in patients with xerostomia.
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CLINICAL_TRIALS trial_result · 2018-09-18Clinical Trial Update: A Safety and Efficacy Study of 552-02 in Subjects With Dry Mouth Associated With Sjogren's Syndrome [Phase 2]
Phase 2 trial evaluating safety and efficacy of 552-02 for dry mouth in Sjögren's syndrome completed.
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CLINICAL_TRIALS trial_result · 2018-08-29Clinical Trial Update: Effects of Photobiomodulation in Salivary Analysis of Chronic Renal Failure Patients [Phase 2]
A Phase 2 trial assessing the effects of photobiomodulation on salivary parameters in patients with xerostomia and chronic renal failure has…
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CLINICAL_TRIALS research · 2018-07-27Clinical Trial Update: Finger-prick Autologous Blood (FAB) for Use in Dry Mouth [NA]
Clinical trial update on Finger-prick Autologous Blood (FAB) for xerostomia, including radiation-induced xerostomia and xerostomia due to hy…
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: A Clinical Study to Evaluate the Efficacy of Three Dry Mouth Relief Products Versus Water [NA]
A completed clinical trial evaluating the efficacy of three dry mouth relief products versus water for xerostomia, with results posted in 20…
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CLINICAL_TRIALS withdrawal · 2018-07-12Clinical Trial Update: Use of Biotene Moisturizing Mouth Spray for Xerostomia Associated With Oral Oxybutynin Use [Phase 4]
Phase 4 trial evaluating Biotene Moisturizing Mouth Spray for xerostomia associated with oral oxybutynin use has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-04-30Clinical Trial Update: Stromal Vascular Fraction for Treatment of Xerostomia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating stromal vascular fraction for xerostomia due to radiotherapy has been withdrawn.
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CLINICAL_TRIALS research · 2018-04-17Clinical Trial Update: Coconut Oil: Managing Radiation-Induced Xerostomia [NA]
An ongoing clinical trial investigates coconut oil as a treatment for radiation-induced xerostomia. The sponsor is Ottawa Hospital Research …