X-linked Agammaglobulinemia
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Immune Regulation in Patients With Common Variable Immunodeficiency and Related Inborn Errors of Immunity (IEI)
The update describes an ongoing NIAID-sponsored study on immune regulation in patients with common variable immunodeficiency and related inb…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Immune Disorder HSCT Protocol [Phase 2]
Phase 2 clinical trial update on a hematopoietic stem cell transplant protocol for several inherited immune deficiency disorders; the study …
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Analysis of the Role of IgE Proteoforms in Health and Disease
KU Leuven is updating on a clinical trial studying the role of IgE proteoforms in health and disease, with recruitment ongoing across severa…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: COVID-19 Vaccine Responses in PIDD Subjects
This clinical trial update describes COVID-19 vaccine responses in patients with primary immunodeficiency diseases (PIDD), including X-linke…
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CLINICAL_TRIALS trial_result · 2018-05-31Clinical Trial Update: Assessment of Immunogenicity of Zostavax® in Patients With Antibody Deficiency 60 Years of Age and Older [NA]
A terminated clinical trial evaluated the immunogenicity of Zostavax in adults aged 60 and older with antibody deficiency conditions.
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplex® 10 and Gammaplex® 5% in Primary Immunodeficiency Diseases [Phase 3]
A Phase 3 bioequivalence study comparing Gammaplex 10% and Gammaplex 5% intravenous immunoglobulin in patients with primary immunodeficiency…
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: A Study to Find Out How Safe and Effective Gammaplex® is in Young People With Primary Immunodeficiency [Phase 4]
Phase 4 study evaluating the safety and effectiveness of Gammaplex in youths with primary immunodeficiency disorders, including Common Varia…
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CLINICAL_TRIALS research · 2014-09-09Clinical Trial Update: Mutation of the BTK Gene and Genotype-phenotype Correlation of Chinese Patients With X-Linked Agammaglobulinemia
This clinical trial update examines BTK gene mutations and genotype-phenotype correlations in Chinese patients with X-linked agammaglobuline…
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CLINICAL_TRIALS trial_result · 2012-10-26Clinical Trial Update: Safety and Efficacy of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID) [Phase 3]
Phase 3 trial results show safety and efficacy of CSL Behring's intravenous immunoglobulin IgPro10 in patients with primary immunodeficienci…
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CLINICAL_TRIALS trial_result · 2012-06-06Clinical Trial Update: Efficacy and Safety of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID) [Phase 3]
Phase 3 trial reports on efficacy and safety of IgPro10 (intravenous immunoglobulin) for primary immunodeficiencies; study completed in agam…
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CLINICAL_TRIALS trial_result · 2011-03-15Clinical Trial Update: Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy [Phase 3]
Phase 3 study of subcutaneous immunoglobulin for IgG replacement in patients with primary immunodeficiencies has completed. Results were pos…
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CLINICAL_TRIALS trial_result · 2010-01-28Clinical Trial Update: Efficacy, Safety and Pharmacokinetics of Gammaplex in Primary Immunodeficiency Diseases. [Phase 3]
Phase 3 study evaluating the efficacy, safety, and pharmacokinetics of Gammaplex in primary immunodeficiency diseases completed with results…
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CLINICAL_TRIALS trial_result · 2009-10-15Clinical Trial Update: Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies [NA]
This clinical trial update notes termination of an allogeneic bone marrow transplantation study for patients with primary immunodeficiencies…
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CLINICAL_TRIALS trial_result · 2009-09-25Clinical Trial Update: Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency Patients [Phase 3]
A Phase 3 trial assessing rapid infusion of intravenous immunoglobulin (IVIG) in patients with primary immunodeficiency has completed.