Wild-type Transthyretin Amyloidosis

• CLINICAL_TRIALS research · 2026-04-16
  Clinical Trial Update: NatiOnal Referral cenTEr Study of Transthyretin Amyloid Cardiomyopathy(ATTR) Patients on Tafamidis

  A clinical trial at a national referral center is evaluating tafamidis in patients with transthyretin amyloid cardiomyopathy (ATTR-CM) and i…

• CLINICAL_TRIALS trial_result · 2026-01-30
  Clinical Trial Update: Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM) [Phase 1]

  Phase 1 study of NTLA-2001 in hereditary transthyretin amyloidosis with polyneuropathy and transthyretin amyloid cardiomyopathy has complete…

• CLINICAL_TRIALS research · 2026-01-16
  Clinical Trial Update: Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy [EARLY_Phase 1]

  An early-phase clinical trial update describing peripheral and autonomic neuropathies in wild-type transthyretin amyloidosis and response to…

• CLINICAL_TRIALS research · 2026-01-02
  Clinical Trial Update: ATTR Amyloid Cardiomyopathy: Characterization of Extracellular Vesicles as Potential Disease Stratifiers and Prognostic Biomarkers

  This clinical trial update describes a study on extracellular vesicles as potential disease stratifiers and prognostic biomarkers for transt…

• CLINICAL_TRIALS research · 2025-11-12
  Clinical Trial Update: Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

  A Columbia University-led clinical trial is recruiting to analyze lumbar spine stenosis specimens for identification of transthyretin-relate…

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• CLINICAL_TRIALS trial_result · 2025-08-15
  Clinical Trial Update: Prevalence of wtATTR-CM After Carpal Tunnel Release Surgery [NA]

  A completed clinical trial evaluating the prevalence of wild-type transthyretin cardiac amyloidosis after carpal tunnel release surgery.

• CLINICAL_TRIALS research · 2025-07-22
  Clinical Trial Update: Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause. [NA]

  A clinical trial evaluating how prevalent wild-type transthyretin cardiac amyloidosis is among patients with polyneuropathy of unknown cause…

• CLINICAL_TRIALS withdrawal · 2016-08-10
  Clinical Trial Update: The Effect of an Antisense Oligonucleotide to Lower Transthyretin (TTR) Levels on the Progression of -Wild-type TTR Involving the Heart [Phase 2]

  A Phase 2 study evaluating an antisense oligonucleotide intended to lower transthyretin (TTR) levels in wild-type transthyretin amyloidosis …