Wet Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-05-07Clinical Trial Update: ESBA1008 Safety, Tolerability and Effects in Wet Age-Related Macular Degeneration (AMD) Patients [Phase 1, Phase 2]
Update on ESBA1008 in wet age-related macular degeneration assessing safety, tolerability, and preliminary effects in Phase 1/2. The trial i…
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CLINICAL_TRIALS trial_result · 2014-01-27Clinical Trial Update: Study to Assess the Effectiveness of Existing Anti vascUlar Endothelial Growth Factor (Anti VEGF) in Patients With Wet Age-related Macular Degeneration (wAMD) (AURA)
This completed clinical trial (AURA) evaluated the effectiveness of existing anti-VEGF therapy for wet age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2013-06-17Clinical Trial Update: Omega-3 Supplementation and Vitreal VEGF Levels in Wet-AMD [NA]
A completed clinical trial evaluated whether omega-3 fatty acid supplementation influences vitreous VEGF levels in wet age-related macular d…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Evaluation of AL-78898A in Exudative Age-Related Macular Degeneration [Phase 2]
Phase 2 clinical trial evaluating AL-78898A for wet age-related macular degeneration has completed, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-04-26Clinical Trial Update: An Open-label Study to Evaluate the Clinical and Economic Benefits of I-Ray in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration [Phase 2]
An open-label Phase 2 clinical trial evaluating the clinical and economic benefits of the I-Ray radiation therapy system for choroidal neova…
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CLINICAL_TRIALS trial_result · 2012-12-19Clinical Trial Update: A Prospective Study Comparing Ranibizumab Plus Dexamethasone Combination Therapy Versus Ranibizumab Monotherapy for Wet AMD [Phase 1, Phase 2]
A completed Phase 1/2 prospective trial comparing ranibizumab plus dexamethasone versus ranibizumab monotherapy for wet age-related macular …
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CLINICAL_TRIALS trial_result · 2012-05-28Clinical Trial Update: Investigates Improvement in Vision Following Switching From Avastin and Macugen Over to Lucentis
A clinical trial update reports vision improvement when wet age-related macular degeneration patients switch from Avastin and Macugen to Luc…
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CLINICAL_TRIALS trial_result · 2012-04-16Clinical Trial Update: Vascular Endothelial Growth Factor VEGF Trap-Eye:Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration(AMD) [Phase 3]
Phase 3 results update for VEGF Trap-Eye (aflibercept) in wet age-related macular degeneration, with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-04-12Clinical Trial Update: Lucentis for Age-related Macular Degeneration Pigment Epithelial Detachments [Phase 2, Phase 3]
A completed Phase 2/Phase 3 clinical trial evaluating Lucentis (ranibizumab) for age-related macular degeneration with pigment epithelial de…
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CLINICAL_TRIALS trial_result · 2012-03-01Clinical Trial Update: Safety and Efficacy of Repeated Intravitreal Administration of Vascular Endothelial Growth Factor (VEGF) Trap in Patients With Wet Age-Related Macular Degeneration (AMD) [Phase 2]
This ClinicalTrials.gov update reports results from a Phase 2 study evaluating repeated intravitreal VEGF Trap (aflibercept) injections for …
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CLINICAL_TRIALS trial_result · 2012-01-23Clinical Trial Update: Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration (AMD) [Phase 3]
Phase 3 results update on VEGF Trap-Eye (aflibercept) for wet age-related macular degeneration, with trial outcomes posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-01-19Clinical Trial Update: Safety & Tolerability of the IRay System in Subjects With Exudative Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD) [Phase 1]
This Phase 1 trial update reports on the safety and tolerability of the IRay System in subjects with exudative choroidal neovascularization …
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CLINICAL_TRIALS withdrawal · 2011-12-30Clinical Trial Update: Study to Evaluate the Safety and Effectiveness of IRay in Wet Age-related Macular Degeneration (AMD) Patients With Recurrent Leakage Secondary to Choroidal Neovascularisation (CNV) [NA]
A clinical trial evaluating IRay for wet age-related macular degeneration with recurrent leakage due to choroidal neovascularization has bee…
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CLINICAL_TRIALS trial_result · 2011-07-27Clinical Trial Update: A Study to Evaluate the Neovista Ophthalmic System for the Treatment of Subfoveal CNV in Patients With AMD That Have Failed Primary Anti-VEGF Therapy [Phase 2]
A Phase 2 trial evaluating the Neovista Ophthalmic System for treating subfoveal CNV in wet age-related macular degeneration patients who fa…
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CLINICAL_TRIALS research · 2011-07-27Clinical Trial Update: A Study of the NeoVista Ophthalmic System for the Treatment of Subfoveal CNV Associated With Wet AMD in Patients That Require Persistent Anti-VEGF Therapy [Phase 1, Phase 2]
Update on a Phase 1/2 study evaluating the NeoVista Ophthalmic System for treating subfoveal CNV associated with wet age-related macular deg…
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CLINICAL_TRIALS trial_result · 2011-07-22Clinical Trial Update: A Study of Genetic and Environmental Factors and Their Effect on Response to Treatment With Lucentis (Ranibizumab) for Wet AMD [Phase 3]
Phase 3 study evaluating how genetic and environmental factors affect response to Lucentis in wet age-related macular degeneration. The tria…
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CLINICAL_TRIALS trial_result · 2011-05-04Clinical Trial Update: Clinical Study Of Pegaptanib Sodium (EYE001) For Wet-Type Age-Related Macular Degeneration [Phase 2]
Pfizer-sponsored Phase 2 trial of pegaptanib sodium (Macugen) for wet age-related macular degeneration has completed, with results posted in…
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CLINICAL_TRIALS research · 2011-02-09Clinical Trial Update: Sub-tenon Triamcinolone Acetonide in Age-Related Macular Degeneration as Adjunct to Ranibizumab [Phase 2]
Phase 2 clinical trial evaluating sub-tenon Triamcinolone acetonide as an adjunct to Ranibizumab for wet age-related macular degeneration. C…
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CLINICAL_TRIALS trial_result · 2010-11-23Clinical Trial Update: Safety and Efficacy of ATG003 in Patients With Wet Age-Related Macular Degeneration (AMD) [Phase 2]
A Phase 2 trial update for ATG003 in wet age-related macular degeneration reports safety and efficacy findings; the study was terminated and…
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CLINICAL_TRIALS research · 2010-06-09Clinical Trial Update: Posterior Macular Adhesion: A Potential Risk Factor for Non-exudative Age Related Macular Degeneration (AMD) to Develop Exudative AMD
A clinical trial update investigates posterior macular adhesion as a potential risk factor for progression from dry age-related macular dege…
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CLINICAL_TRIALS trial_result · 2008-11-14Clinical Trial Update: Safety and Efficacy of Oral PTK787 in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration (AMD) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the safety and efficacy of oral PTK787 (Vatalanib) in patients with subfoveal choroidal neovascularizati…
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CLINICAL_TRIALS trial_result · 2008-08-05Clinical Trial Update: Safety and Efficacy Study of Small Interfering Ribonucleic Acid (RNA) Molecule (Cand5) to Treat Wet Age-Related Macular Degeneration [Phase 2]
A Phase 2 trial evaluating the safety and efficacy of the Cand5 RNA molecule for wet age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2008-01-09Clinical Trial Update: MSI-1256F (Squalamine Lactate) in Combination With Verteporfin in Patients With "Wet" Age-Related Macular Degeneration (AMD) [Phase 2]
Phase 2 trial of MSI-1256F (squalamine lactate) in combination with verteporfin for wet age-related macular degeneration was terminated. Thi…
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CLINICAL_TRIALS trial_result · 2007-12-28Clinical Trial Update: Safety and Tolerability of an Intravenous Infusion of ACZ885 in Patients With Wet Age-Related Macular Degeneration [Phase 1]
Phase 1 safety and tolerability study of intravenous ACZ885 (canakinumab) in patients with wet age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2007-01-15Clinical Trial Update: A Clinical Trial to Explore the Safety and Efficacy of Three Different Doses of Pegaptanib Sodium in Patients With Wet Age-Related Macular Degeneration (AMD) [Phase 4]
A Phase 4 trial evaluating three doses of pegaptanib sodium for wet age-related macular degeneration was terminated.