Wet Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: Real Life of Aflibercept in France in Patients Refractory to Ranibizumab: Observational Study in Wet AMD
A completed observational study in France evaluates real-world outcomes of aflibercept in patients with wet age-related macular degeneration…
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Investigating the Effectiveness of Eylea in Patients With Wet Age-related Macular Degeneration
A clinical trial evaluating the effectiveness of Eylea (aflibercept) in wet age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: Japanese Treat and Extend Study of Aflibercept in Neovascular Age-related Macular Degeneration [Phase 4]
Phase 4 trial update for aflibercept in wet age-related macular degeneration (wet AMD) from the Japanese Treat and Extend study; results pos…
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CLINICAL_TRIALS research · 2017-08-22Clinical Trial Update: Caregiver Burden of Wet Age-related Macular Degeneration (wAMD) in Japan
Bayer-sponsored clinical trial in Japan evaluating caregiver burden in patients with wet age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: A Prospective, Observational, Multicentre, 2 Year Study Evaluating the Use of Eylea (Aflibercept) for the Treatment of Neovascular (Wet) Age-related Macular Degeneration in UK NHS Opthalmology Clinics
This clinical trial update notes the termination of a prospective observational multicenter study evaluating the use of Eylea (aflibercept) …
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CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: Safety Evaluation of China Patients: Long-term Treatment Outcome of Conbercept Ophthalmic Injection in Real Word（STONE）
This clinical trial update reports long-term safety and treatment outcomes of intravitreal conbercept for wet age-related macular degenerati…
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CLINICAL_TRIALS withdrawal · 2017-02-15Clinical Trial Update: CANadian Study in Patients With Wet AMD, Evaluating the Efficacy and Safety of Switching From Intravitreal Aflibercept to RanIbizumab [Phase 4]
This clinical trial was withdrawn; it investigated switching from aflibercept (Eylea) to ranibizumab (Lucentis) for wet age-related macular …
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CLINICAL_TRIALS trial_result · 2017-01-02Clinical Trial Update: A Study of Intravitreal Injections of 2.0mg Ranibizumab in Subjects With Chronic Fluid On OCT Post Multiple Injections With Ranibizumab (Super-dose Anti-VEgf SAVE Trial) [Phase 1, Phase 2]
This terminated Phase 1/2 trial (Super-dose Anti-VEGF SAVE Trial) evaluated intravitreal 2.0 mg ranibizumab for chronic OCT fluid after prio…
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Evaluation of Safety and Efficacy of Once Monthly Ranibizumab Injections in Chinese Patients With Wet Age Related Macular Degeneration (AMD) Patients [Phase 3]
Phase 3 trial evaluating the safety and efficacy of once-monthly ranibizumab injections for wet age-related macular degeneration in Chinese …
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of RO6867461 Administered in Single- and Multiple-Ascending Doses in Patients With Wet Age-Related Macular Degeneration [Phase 1]
A Phase 1 study of RO6867461 in single- and multiple-ascending dose cohorts for wet age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Pilot Study of Lucentis Combined With Proton Beam Irradiation in Treating Wet Age-related Macular Degeneration [EARLY_Phase 1]
An early-phase pilot study evaluated Lucentis (ranibizumab) in combination with proton beam irradiation for wet age-related macular degenera…
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CLINICAL_TRIALS trial_result · 2016-06-27Clinical Trial Update: A 4 Week Study With BI 144807 in Patients >= 50 Years With Wet Age Related Macular Degeneration [Phase 2]
A 4-week Phase 2 trial of BI 144807 in adults 50 and older with wet age-related macular degeneration completed, with results posted on 2016-…
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CLINICAL_TRIALS trial_result · 2016-05-23Clinical Trial Update: Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting
A completed real-world study evaluating the effectiveness and safety of ranibizumab in patients with wet age-related macular degeneration, d…
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CLINICAL_TRIALS withdrawal · 2016-03-31Clinical Trial Update: Safety and Efficacy Study of BCD-021 Compared to Lucentis® in Patients With Neovascular Wet Age-related Macular Degeneration [Phase 3]
A Phase 3 safety and efficacy trial comparing Biocad's BCD-021 to Lucentis for wet age-related macular degeneration has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-03-29Clinical Trial Update: HiPED - High Dose Lucentis for Persistent Pigment Epithelial Detachments in Age-related Macular Degeneration [Phase 2]
The Phase 2 HiPED trial evaluating high-dose ranibizumab (Lucentis) for persistent pigment epithelial detachments in age-related macular deg…
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CLINICAL_TRIALS trial_result · 2015-10-30Clinical Trial Update: Treat and Extend Therapy Study Using Intravitreal Aflibercept for Patients Exited From Protocol VGFT-OD 0910 [Phase 4]
Phase 4 clinical trial update describing a treat-and-extend study of intravitreal aflibercept for patients who exited protocol VGFT-OD 0910 …
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CLINICAL_TRIALS trial_result · 2015-09-14Clinical Trial Update: Non-Persistence/Non-Adherence (NP/NA) in Wet Age-related Macular Degeneration (wAMD) Patients in Germany
A Bayer-sponsored clinical trial conducted in Germany examined non-persistence and non-adherence in patients with wet age-related macular de…
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CLINICAL_TRIALS trial_result · 2015-03-13Clinical Trial Update: VEGF Trap-Eye: Investigation of Efficacy and Safety in Chinese Subjects With Wet AMD (Age-Related Macular Degeneration) [Phase 3]
Phase 3 clinical trial update assessing efficacy and safety of VEGF Trap-Eye (aflibercept) in Chinese patients with wet age-related macular …
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: Phase 1 Safety Study With Intravitreal (IVT) REGN2176-3 in Patients Aged 50 Years and Older With Wet AMD [Phase 1]
This update reports the completion of a Phase 1 intravitreal safety study of REGN2176-3 in adults 50 years and older with wet age-related ma…
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CLINICAL_TRIALS trial_result · 2014-12-17Clinical Trial Update: Analysis of Growth Factors in Patients Undergoing Lucentis or Avastin Injections for Diabetic Macular Edema and Exudative Macular Degeneration [NA]
Clinical trial update analyzing growth factors in patients receiving Lucentis or Avastin injections for diabetic macular edema and wet age-r…
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: INTREPID - IRay Plus Anti-VEGF Treatment For Patients With Wet AMD [Phase 2]
INTREPID is a Phase 2 trial evaluating IRay Plus in combination with anti-VEGF treatment for wet age-related macular degeneration. The study…
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CLINICAL_TRIALS trial_result · 2014-10-06Clinical Trial Update: Safety & Efficacy Study Evaluating the Combination of Bevasiranib & Lucentis Therapy in Wet AMD [Phase 3]
Phase 3 trial evaluating Bevasiranib plus Lucentis for wet age-related macular degeneration was terminated, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: Study to Assess the EffectiVeness of exIsting Anti-vascular Endothelial groWth Factor (Anti-VEGF) Treatment Regimens in Patients With Wet Age-related Macular Degeneration
This completed clinical trial evaluated the effectiveness of existing anti-VEGF treatment regimens in patients with wet age-related macular …
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CLINICAL_TRIALS trial_result · 2014-07-22Clinical Trial Update: An Open, Single-center, Safety and Efficacy Study of Conbercept in Patients With Very Low Vision Secondary to Wet Age-related Macular Degeneration (wAMD) [Phase 2]
This open, single-center Phase 2 trial evaluates the safety and efficacy of Conbercept in patients with very low vision due to wet age-relat…
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CLINICAL_TRIALS trial_result · 2014-05-12Clinical Trial Update: Study of MP0112 Intravitreal Injection in Patients With Wet Age Related Macular Degeneration [Phase 1]
Allergan's Phase 1 trial of MP0112 given by intravitreal injection for wet age-related macular degeneration was terminated; results were pos…