Venous Leg Ulcers
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Clinical Trial Evaluating NuShield® Plus Standard of Care (SOC) Versus Standard of Care (SOC) Alone in the Management of Non-Healing Venous Leg Ulcers (VLUs) [NA]
A clinical trial is evaluating NuShield with standard of care versus standard of care alone for non-healing venous leg ulcers; the study is …
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE) [Phase 3]
A Phase 3 double-blind trial is evaluating the efficacy and safety of EscharEx for debridement of venous leg ulcers and is currently recruit…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Feasibility and Tolerance Study for the Treatment of Varicose Ulcers by Cyanoacrylate Glue (ETUVVE) [NA]
A completed feasibility and tolerance study evaluating treatment of varicose/venous ulcers using cyanoacrylate glue (ETUVVE).
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Modified Platform Trial Assessing Multiple Umbilical Cord-based CAMPs and SOC v SOC Alone in the Treatment of Hard-to-Heal VLUs [NA]
A modified platform trial is evaluating multiple umbilical cord-based CAMPs in addition to standard of care for hard-to-heal venous leg ulce…
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: Chemical Debridement and Leg Ulcers [NA]
This update reports the completion of a clinical trial evaluating chemical debridement for venous leg ulcers. The study also involved mixed …
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CLINICAL_TRIALS safety_alert · 2026-02-19Clinical Trial Update: Safety of the Sonablate HIFU System for the Ablation of Incompetent Veins of the Periphery [NA]
A clinical trial update indicates ongoing safety evaluation of the Sonablate HIFU System for ablation of incompetent peripheral veins; the s…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Effect of Photobiomodulation on Healing of Venous Leg Ulcers [NA]
Clinical trial evaluating whether photobiomodulation aids healing of venous leg ulcers; the study status is not yet recruiting.
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Smart Bandage With Telemonitoring vs Standard Care for Venous Leg Ulcer: Randomized Trial [NA]
A randomized trial comparing a smart bandage with telemonitoring to standard care for venous leg ulcers; recruitment has not yet started.
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CLINICAL_TRIALS other · 2025-12-16Clinical Trial Update: Nonhealing Venous Leg Ulcers Treated With a Standard of Care (SoC) Alone or Standard of Care and Dehydrated Human Placenta Tissue (dHPT) With Crossover [Phase 4]
Clinical trial update for NCT07230340 describes a Phase 4 study in venous leg ulcers comparing standard of care alone to standard of care pl…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of CVU (Phase IIb) [Phase 2]
A Phase IIb trial evaluating allogeneic ABCB5-positive dermal mesenchymal stromal cells for chronic venous ulcers has completed treatment ac…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Trial to Evaluate Cyclical Topical Wound Oxygen Therapy in the Treatment of Chronic Venous Leg Ulcers [Phase 4]
A Phase 4 clinical trial is evaluating cyclical topical wound oxygen therapy for chronic venous leg ulcers. The study is currently recruitin…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Efficacy of Carbonlife Amniotic Tissue Product in the Treatment of Chronic Wounds [Phase 3]
This document reports on a Phase 3 clinical trial evaluating the efficacy of Carbonlife Amniotic Tissue Product for treating chronic wounds;…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: A RCT Evaluating Efficacy of Type-I Collagen Skin Substitute vs. Human Amnion Membrane in Treatment of Venous Leg Ulcers [NA]
A randomized controlled trial comparing Type-I Collagen Skin Substitute with Human Amnion Membrane for treating venous leg ulcers has comple…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Research of Prognostic Factors Associated With Healing of Venous Leg Ulcers [NA]
This update summarizes completed research investigating prognostic factors associated with healing of venous leg ulcers.
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Assessing Connected-Health, Pressure-Monitoring Technology for Improving Compression Therapy in Venous Leg Ulcer Treatment [NA]
Clinical trial evaluating connected-health and pressure-monitoring technology to improve compression therapy for venous leg ulcers; status i…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Educational Interventions in Venous Leg Ulcer [NA]
This clinical trial update describes educational interventions for venous leg ulcers, sponsored by the University of Padova. The study statu…
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: Observational Study to Investigate the Use of Sterilized Porcine Placental Tissue in the Treatment of Chronic VLU
An observational clinical trial evaluating sterilized porcine placental tissue for venous leg ulcers; the study is currently active but not …
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: A RCT Evaluating the Clinical Benefit of a Silver Dressing in the Treatment of Venous Leg Ulcers [NA]
This document provides an update on a randomized controlled trial evaluating a silver dressing for venous leg ulcers. The trial status is co…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: A Research Study to Evaluate the Safety and Potential Efficacy of ON101 Cream for the Treatment of Venous Leg Ulcers. [Phase 4]
A Phase 4 clinical trial evaluating ON101 Cream for venous leg ulcers has been terminated, with safety and potential efficacy data not advan…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Clinical Trial Evaluating an Amnion Membrane Allograft Intended for Use in the Management of Non- Healing Venous Leg Ulcers Versus Standard Of Care Alone [NA]
This Clinical Trials update notes a study evaluating an amnion membrane allograft for non-healing venous leg ulcers versus standard of care,…
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: Impact of Omega-3 Fatty Acid Oral Therapy on Healing of Chronic Venous Leg Ulcers in Older Adults [NA]
This clinical trial evaluated the effect of oral omega-3 fatty acids on healing of chronic venous leg ulcers in older adults. The study stat…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Clinical Study to Evaluate the Safety and the Efficacy of EscharEx Drug Product (EX-03 Formulation) and Its Placebo Compared to Collagenase, Non-surgical Standard of Care, in Patients With Venous Leg Ulcers [Phase 2]
Phase 2 clinical trial assessing safety and efficacy of EscharEx EX-03 formulation versus placebo and collagenase for venous leg ulcers; sta…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Intravascular Ultrasound-Guided Intervention for Venous Leg Ulcers (IGuideU) [NA]
A terminated clinical trial evaluating intravascular ultrasound-guided intervention for venous leg ulcers has posted results.
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CLINICAL_TRIALS research · 2024-05-06Clinical Trial Update: A Clinical Investigation to Follow the Progress of Exuding Chronic Venous Leg Ulcers Using a Non-Bordered Foam Dressing [NA]
Clinical trial evaluates a non-bordered foam dressing for exuding chronic venous leg ulcers; currently recruiting.
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CLINICAL_TRIALS trial_result · 2021-05-19Clinical Trial Update: Blu Light for Ulcers Reduction [NA]
Clinical trial completed assessing Blu Light therapy for venous leg ulcers, dehiscence, and surgical wounds with results posted in 2021.