Vaso-occlusive Crisis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-28Clinical Trial Results: Hyperbaric Oxygen Therapy in Sickle Cell Pain [NA]
Clinical trial results evaluate hyperbaric oxygen therapy for vaso-occlusive crisis in sickle cell disease; results have been posted after c…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Efficacy of Liberal Versus Restricted IV Fluid Approach in the Management of Sickle Cell Vaso-Occlusive Crisis [NA]
A clinical trial is comparing liberal versus restricted intravenous fluid strategies to manage sickle cell disease-related vaso-occlusive cr…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Morphine Clearance and Glomerular Filtration in Sickle Cell Patients in Crisis in Intensive Care [NA]
A clinical trial update announcing recruitment for a study on morphine clearance and glomerular filtration in sickle cell crisis patients in…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease [NA]
Clinical trial update notes ongoing study on using virtual reality technology to manage pain during vaso-occlusive crises in sickle cell dis…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell Patients
A clinical trial update indicates the study is currently recruiting to assess whether regional anesthesia can influence inflammatory pathway…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Intranasal Ketamine for Pain Control in Patients with Sickle Cell Disease and Vaso-occlusive Episode (VOE) in the PED [Phase 3]
A Phase 3 trial evaluating intranasal ketamine for pain control during vaso-occlusive episodes in children with sickle cell disease was term…
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CLINICAL_TRIALS research · 2024-08-30Clinical Trial Update: Ketorolac for Acute Vaso-Occlusive Crisis in Pediatric Sickle Cell Disease [Phase 4]
Phase 4 clinical trial evaluating ketorolac for acute vaso-occlusive crisis in pediatric sickle cell disease; status is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Nitrous Oxide Analgesia Vaso-occlusive Crisis [Phase 2]
Phase 2 trial evaluating nitrous oxide analgesia for vaso-occlusive crisis in sickle cell disease has completed, with results posted on 2024…
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CLINICAL_TRIALS trial_result · 2023-12-26Clinical Trial Update: Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric [Phase 3]
Phase 3 clinical trial evaluating intranasal sufentanil for analgesia in pediatric severe sickle cell vaso-occlusive crisis; not yet recruit…
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CLINICAL_TRIALS trial_result · 2023-03-07Clinical Trial Update: Evaluation of the Efficacy of Intra-nasal Sufentanil for Analgesia of Vaso-occlusive Crisis in Sickle-cell Adults. [Phase 3]
Phase 3 clinical trial evaluating intra-nasal sufentanil for analgesia in adults with vaso-occlusive crisis due to sickle cell disease.
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CLINICAL_TRIALS trial_result · 2022-11-02Clinical Trial Update: Hyperbaric-oxygen Therapy (HBOT) Versus Placebo for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD) [Phase 3]
A Phase 3 clinical trial evaluating hyperbaric oxygen therapy versus placebo for vaso-occlusive crisis in sickle cell disease; current statu…
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CLINICAL_TRIALS trial_result · 2021-04-20Clinical Trial Update: Adjuvant Low-dose Ketamine in Pediatric Sickle Cell Vaso-occlusive Crisis [Phase 2]
Phase 2 clinical trial evaluating adjuvant low-dose ketamine for pediatric sickle cell vaso-occlusive crisis has completed with results post…
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CLINICAL_TRIALS trial_result · 2021-02-10Clinical Trial Update: Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease [Phase 3]
Phase 3 trial of rivipansel (GMI-1070) in hospitalized sickle cell vaso-occlusive crises was terminated.
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CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell Anemia [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating different treatment modalities for managing painful crisis in pediatric sickle cell disease has complete…
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CLINICAL_TRIALS trial_result · 2020-07-07Clinical Trial Update: Steroid Treatment for Sickle Cell Pain Crisis [Phase 3]
Phase 3 trial evaluating steroid treatment for pain crisis in sickle cell disease; study terminated, results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-05-13Clinical Trial Update: Study of GMI-1070 for the Treatment of Sickle Cell Pain Crisis [Phase 2]
Phase 2 trial update for GMI-1070 in sickle cell pain crisis (vaso-occlusive crisis) has completed.
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CLINICAL_TRIALS trial_result · 2018-05-23Clinical Trial Update: A Study of SANGUINATE for the Treatment of Vaso-occlusive Crisis (VOC) in Adult Sickle Cell Disease Patients [Phase 2]
A Phase 2 trial evaluating SANGUINATE for treatment of vaso-occlusive crisis in adults with sickle cell disease has completed.
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CLINICAL_TRIALS research · 2018-05-03Clinical Trial Update: A Comprehensive Care Plan for Pediatric Patients With Vaso-Occlusive Crises [NA]
A clinical trial update describes a comprehensive care plan for pediatric patients with vaso-occlusive crises, sponsored by Valley Anesthesi…
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CLINICAL_TRIALS withdrawal · 2017-03-24Clinical Trial Update: Comparison of Patient Controlled Analgesia (PCA) Versus Bolus Narcotic Therapy for the Treatment of Vaso-Occlusive Crisis (VOC) [Phase 2]
A Phase 2 trial comparing patient-controlled analgesia versus bolus narcotic therapy for vaso-occlusive crisis in sickle cell disease was wi…
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC) [Phase 3]
Phase 3 EPIC trial evaluating purified poloxamer 188 for vaso-occlusive crisis in sickle cell disease has completed; no efficacy results are…
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CLINICAL_TRIALS trial_result · 2014-03-04Clinical Trial Update: IMPACTS Trial: Investigation of the Modulation of Phospholipase in Acute Chest Syndrome [Phase 2]
A Phase 2 study (IMPACTS) evaluating varespladib, a phospholipase A2 inhibitor, for acute chest syndrome in sickle cell disease has complete…