Valvular Heart Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: ADVANCE Direct Aortic Study
Completed clinical trial update for the ADVANCE Direct Aortic study; results posted in 2018 for aortic stenosis and valvular heart disease.
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: CoreValve Advance-II Study: Prospective International Post-market Study
Prospective international post-market study (CoreValve Advance-II) completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Text Message Intervention to Improve Cardiac Rehab Participation [NA]
This entry reports a terminated clinical trial evaluating a text message intervention to boost participation in cardiac rehabilitation.
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CLINICAL_TRIALS research · 2018-06-28Clinical Trial Update: Pre-habilitation of Patients Scheduled for Cardiac Valve Surgery [NA]
An ongoing clinical trial evaluating prehabilitation for patients scheduled for cardiac valve surgery, sponsored by Sheba Medical Center, in…
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CLINICAL_TRIALS trial_result · 2018-05-08Clinical Trial Update: Changes in the Tricuspid Valve Complex Induced by Mitral Valve Annuloplasty
A clinical trial investigated how mitral valve annuloplasty affects the tricuspid valve complex; the study has been terminated.
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CLINICAL_TRIALS research · 2018-04-12Clinical Trial Update: Correlation of Brain and Thenar Muscle Oximetry During Cardiac Surgery With Parameters of Acute Kidney Injury
A clinical trial evaluating whether brain and thenar muscle oxygenation during cardiac surgery correlates with parameters of acute kidney in…
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CLINICAL_TRIALS trial_result · 2018-04-02Clinical Trial Update: NeoChord TACT Post-Market Surveillance Registry
This entry reports the completed status and posted results of the NeoChord TACT post-market surveillance registry for mitral valve insuffici…
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CLINICAL_TRIALS trial_result · 2018-01-18Clinical Trial Update: Effect of Anesthetics on CD39 and CD73 After Open-heart Surgery [Phase 4]
Phase 4 trial updating the effects of anesthetics on CD39 and CD73 after open-heart surgery for valvular and aortic disease (completed).
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Effects of Prophylactic Desmopressin on Blood Coagulation Parameters in Heart Valve Surgery [Phase 4]
Phase 4 clinical trial evaluating the effects of prophylactic desmopressin on blood coagulation parameters in patients undergoing heart valv…
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CLINICAL_TRIALS research · 2017-11-17Clinical Trial Update: Medtronic's MOSAIC Bioprosthesis Versus Baxter Carpentier-Edwards SAV Porcine Valve [NA]
A completed clinical trial comparing Medtronic's MOSAIC Bioprosthesis with Baxter's Carpentier-Edwards SAV Porcine Valve for cardiac valve r…
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Comparative Effects of Dexmedetomidine and Ketofol for Sedation in Patients Undergoing Trans-esophageal Echocardiography [Phase 4]
Phase 4 trial comparing dexmedetomidine and ketofol for sedation during trans-esophageal echocardiography has completed.
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CLINICAL_TRIALS trial_result · 2017-08-31Clinical Trial Update: Randomized Study of the Use of Warfarin During Pacemaker or ICD Implantation in Patients Requiring Long Term Anticoagulation [NA]
This clinical trial update notes the completion and posting of results for a randomized study evaluating warfarin use during pacemaker or IC…
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CLINICAL_TRIALS trial_result · 2017-08-24Clinical Trial Update: The Concomitant Cryomaze Procedure Using Nitreous Oxide Cryoprobe: Comparison With Argon Based Cryoprobe [NA]
Completed clinical trial comparing a nitrous oxide cryoprobe with an argon-based cryoprobe for the concomitant Cryomaze procedure in patient…
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: D-Dimer Determined Anticoagulation INTENSITY in Patients With Mechanical Valve Replacement
This clinical trial evaluated whether D-Dimer–guided anticoagulation intensity could optimize management in patients with mechanical heart v…
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: The Safety and Efficacy of the Enhanced Recovery After Surgery(ERAS)Applied on Cardiac Surgery With Cardiopulmonary Bypass [Phase 2]
Phase 2 study evaluating the safety and efficacy of Enhanced Recovery After Surgery (ERAS) applied to cardiac surgery with cardiopulmonary b…
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Post-Approval Study Protocol of the St. Jude Medical Trifecta Valve [NA]
This document reports the completion and results posting of Abbott's post-approval study for the St. Jude Medical Trifecta Valve used in val…
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CLINICAL_TRIALS research · 2017-05-30Clinical Trial Update: Concomitant Surgical Atrial Fibrillation Ablation in Double Valve Replacement
This ClinicalTrials.gov entry describes a study evaluating concomitant surgical atrial fibrillation ablation during double valve replacement…
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CLINICAL_TRIALS trial_result · 2017-05-25Clinical Trial Update: ATS 3f(r) Aortic Bioprosthesis Model 1000 Post Approval Study [NA]
This clinical trial update reports results from the post-approval study of Medtronic's ATS 3f(r) Aortic Bioprosthesis Model 1000. The study …
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: The Short Form-36: Pre- Versus Post-Surgical Administration in Cardiac Surgery Patients
This clinical trial update discusses the timing of Short Form-36 questionnaire administration before vs after surgery in patients undergoing…
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CLINICAL_TRIALS trial_result · 2017-01-09Clinical Trial Update: Pharmacogenetic Dosage Algorithm for Acenocoumarol
A completed clinical trial evaluating a pharmacogenetic dosing algorithm for acenocoumarol intended to tailor anticoagulation dosing. Condit…
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CLINICAL_TRIALS research · 2017-01-06Clinical Trial Update: Effects of Hyperoxia on Open Heart Surgery [NA]
This entry reports an ongoing clinical trial hosted by Istanbul University studying the effects of hyperoxia during open-heart surgery in pa…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: Effect of Isoflurane on Tissue Doppler Imaging of Mitral Annulus During Cardiac Surgery [NA]
A completed clinical trial evaluated the effect of isoflurane anesthesia on tissue Doppler imaging of the mitral annulus during cardiac surg…
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CLINICAL_TRIALS research · 2016-10-21Clinical Trial Update: Strategies for Revascularization in Patients Undergoing Heart Valve Surgery With Concomitant Coronary Artery Disease [NA]
A clinical trial update addressing strategies for revascularization in patients undergoing heart valve surgery with concomitant coronary art…
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: Sildenafil for Secondary Pulmonary Hypertension Due to Valvular Disease [Phase 4]
Phase 4 trial update evaluating sildenafil for secondary pulmonary hypertension due to valvular heart disease. The study status is completed…
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CLINICAL_TRIALS trial_result · 2016-09-20Clinical Trial Update: coRonary assEssment of Preoperative vaLvulopathy pAtients Using ComputEd Tomographic Angiography (REPLACE)
This is a clinical trial update for the REPLACE study, which evaluates preoperative coronary assessment in patients with valvular heart dise…