Valvular Heart Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: BIOVALVE - I / II Clincial Investigation [NA]
This document reports a completed BIOVALVE I/II clinical investigation sponsored by Biotronik AG. The study evaluated valvular heart disease…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: SATURN Transcatheter Mitral Valve Replacement for Functional Mitral Regurgitation [NA]
Clinical trial update for InnovHeart's SATURN transcatheter mitral valve replacement addressing functional mitral regurgitation. The current…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: 18F-Fluoride Assessment of Aortic Bioprosthesis Durability and Outcome [NA]
A completed clinical trial evaluating 18F-Fluoride imaging to assess the durability and outcomes of aortic bioprosthetic heart valves.
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CLINICAL_TRIALS research · 2024-05-20Clinical Trial Update: Health Data Warehouse on Aortic Insufficiency
This clinical trial update reports a health data warehouse study led by Lille Catholic University, currently active but not recruiting, focu…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Valvular Microbiota and Valvulopathy [NA]
Clinical trial update indicates the study on valvulopathy is currently recruiting, with the sponsor listed as University Hospital, Toulouse,…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Warfarin Patient Self-management Implementation in the US Healthcare System [NA]
This clinical trial evaluates implementing warfarin patient self-management in the US healthcare system for patients with atrial fibrillatio…
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: Detection of Valvular Heart Disease Using Artificial Intelligence-based Stethoscope
A clinical trial evaluating an AI-based stethoscope for detecting valvular heart disease is currently recruiting, sponsored by Xiao-dong Zhu…
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CLINICAL_TRIALS trial_result · 2024-03-21Clinical Trial Update: Sugammadex Titration in Cardiac Surgery Patients [Phase 4]
A Phase 4 clinical trial updating sugammadex titration in cardiac surgery patients has completed with results posted in 2024.
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FDA approval · 2024-03-01FDA Approved: DEFINITY — Supplemental Application (Lantheus Medical Imaging, Inc.)
FDA approved a supplemental application for DEFINITY (perflutren) from Lantheus Medical Imaging, Inc., resulting in updated labeling and/or …
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: Topical Effect of Tranexamic Acid in Postoperative Bleeding and Blood Products Transfusion After Cardiac Surgery [Phase 4]
Phase 4 trial update studying topical tranexamic acid to reduce postoperative bleeding and blood product transfusion after cardiac surgery i…
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CLINICAL_TRIALS trial_result · 2022-04-12Clinical Trial Update: RIvaroxaban for Valvular Heart diseasE and atRial Fibrillation Trial -RIVER Trial [Phase 2]
Phase 2 trial update for rivaroxaban in valvular heart disease with atrial fibrillation (RIVER trial) has completed.
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CLINICAL_TRIALS trial_result · 2021-10-21Clinical Trial Update: A Trial to Evaluate the Effect of Rosuvastatin on Inflammation in Patients Undergoing Isolated Cardiac Valve Surgery [Phase 3]
Phase 3 trial assessing rosuvastatin's effect on inflammation in patients undergoing isolated valvular cardiac surgery has completed.
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CLINICAL_TRIALS trial_result · 2021-10-13Clinical Trial Update: Pre-operative Rehabilitation for Reduction of Hospitalization After Coronary Bypass and Valvular Surgery. [NA]
A clinical trial evaluated a pre-operative rehabilitation program aimed at reducing hospitalization for patients awaiting coronary artery by…
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CLINICAL_TRIALS trial_result · 2021-09-22Clinical Trial Update: Different Modalities of Analgesia in Open Heart Surgeries in Mansoura University [Phase 4]
Phase 4 clinical trial updating analgesia modalities in open-heart surgery patients.
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CLINICAL_TRIALS trial_result · 2021-01-13Clinical Trial Update: Dabigatran Versus Conventional Treatment for Prevention of Silent Cerebral Infarct in Atrial Fibrillation Associated With Valvular Disease [Phase 4]
Phase 4 trial comparing dabigatran to conventional treatment for preventing silent cerebral infarcts in patients with atrial fibrillation an…
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CLINICAL_TRIALS trial_result · 2020-03-26Clinical Trial Update: The Impact of Vitamin C on Postoperative Acute Kidney Injury in Risk Patients Undergoing Valvular Heart Surgery [Phase 4]
Phase 4 clinical trial evaluating the impact of vitamin C on postoperative acute kidney injury in high-risk patients undergoing valvular hea…
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CLINICAL_TRIALS trial_result · 2020-03-24Clinical Trial Update: Hypertonic Saline for Fluid Resuscitation After Cardiac Surgery [Phase 4]
A Phase 4 clinical trial evaluating hypertonic saline for fluid resuscitation after cardiac surgery has completed.
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FDA approval · 2019-09-26FDA Approved: WARFARIN SODIUM — Supplemental Application (Exelan Pharmaceuticals Inc.)
The FDA approved a supplemental application for Warfarin Sodium by Exelan Pharmaceuticals. This action updates the regulatory status of this…
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FDA approval · 2019-09-20FDA Approved: JANTOVEN — Supplemental Application (Upsher-Smith Laboratories, LLC)
The FDA approved a supplemental application for JANTOVEN (warfarin sodium) submitted by Upsher-Smith Laboratories, LLC.
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CLINICAL_TRIALS withdrawal · 2019-02-04Clinical Trial Update: ACTION - Anticoagulation Treatment Influence on Post-operative Patients [Phase 4]
The ACTION Phase 4 trial evaluating anticoagulation treatment in post-operative patients with valvular heart disease has been withdrawn.
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CLINICAL_TRIALS research · 2019-02-04Clinical Trial Update: Observational Study of Prosthetic Tissue Aortic and Mitral Heart Valve [NA]
An observational study of prosthetic tissue aortic and mitral heart valves sponsored by Abbott Medical Devices has completed, with Valvular …
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CLINICAL_TRIALS withdrawal · 2019-02-01Clinical Trial Update: Percutaneous Device Closure for Significant Paravalvular Leakage After Transcatheter or Surgical Valve Replacement [NA]
A clinical trial evaluating percutaneous device closure for significant paravalvular leakage after transcatheter or surgical valve replaceme…
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CLINICAL_TRIALS trial_result · 2019-01-29Clinical Trial Update: Role of High Mobility Group Box 1 as a Prognostic Biomarker in Patients Undergoing Valvular Heart Surgery
Completed clinical trial evaluating high mobility group box 1 (HMGB1) as a prognostic biomarker in patients undergoing valvular heart surger…
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: The Effect of Remote Ischemic Postconditioning on Postoperative Renal Dysfunction in Patients Undergoing Valvular Heart Surgery [NA]
A completed clinical trial evaluating whether remote ischemic postconditioning can reduce postoperative renal dysfunction in patients underg…
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CLINICAL_TRIALS research · 2018-08-01Clinical Trial Update: Individualised Follow-up After Valve Surgery [NA]
A completed clinical trial evaluating individualized follow-up after valve surgery. The study examined readmission outcomes in valvular hear…