Uterine Leiomyosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Ph 2 Elacestrant in ER Positive Uterine Sarcomas [Phase 2]
Phase 2 clinical trial of elacestrant for estrogen receptor-positive uterine sarcomas is recruiting.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Letrozole in Uterine Leiomyosarcoma [Phase 2]
A Phase 2 clinical trial is evaluating the aromatase inhibitor letrozole for uterine leiomyosarcoma and is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Phase II Decentralized Pragmatic Trial of Adjuvant Doxorubicin - Trabectedin Chemotherapy in uLMS [Phase 2]
Phase II decentralized pragmatic trial evaluating adjuvant doxorubicin and trabectedin chemotherapy for uterine leiomyosarcoma; currently re…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial evaluating cabozantinib in combination with temozolomide for unresectable or metastatic leiomyosarcoma and other soft…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine Leiomyosarcoma [Phase 2]
Phase 2 clinical trial update for cytoreductive surgery with HIPEC using gemcitabine and dacarbazine in uterine leiomyosarcoma; the study is…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Interest of Post-operative Chemotherapy in Patients With Localised Uterine Leiomyosarcoma Suspected of Having a High Risk of Recurrence Based on a Biological Test Performed on the Tumour [Phase 2]
A Phase 2 trial evaluating whether post-operative chemotherapy benefits patients with localized uterine leiomyosarcoma assessed as high-risk…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: Combined CRS With HIPEC in Women With Inadvertently Morcellated uLMS
A completed clinical trial evaluating cytoreductive surgery with HIPEC in women with inadvertently morcellated uterine leiomyosarcoma.
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CLINICAL_TRIALS research · 2024-08-30Clinical Trial Update: Evaluation of Ultrasound-guided Transuterine Vaginal Biopsy Technique in Uterine Fibromatous Disease [NA]
A clinical trial evaluating ultrasound-guided transuterine vaginal biopsy for uterine fibromatous disease; the study is currently not yet re…
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CLINICAL_TRIALS research · 2024-07-25Clinical Trial Update: The Role of Pre-Surgical Tru - Cut Biopsy in the Management of Atypical Myometrial Lesions
This clinical trial examines the role of pre-surgical Tru-Cut biopsy in the management of atypical myometrial lesions, including uterine lei…
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CLINICAL_TRIALS trial_result · 2024-05-28Clinical Trial Update: FUlvestrant in Gynecological Cancers That Are Potentially Hormone Sensitive: the FUCHSia Study [Phase 2]
A Phase 2 study (FUCHSia) evaluating fulvestrant for hormone-sensitive gynecologic cancers has completed, investigating its activity in uter…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma [Phase 2]
Phase II trial evaluating the combination of olaparib and temozolomide for advanced uterine leiomyosarcoma; results have been posted.
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CLINICAL_TRIALS trial_result · 2021-12-30Clinical Trial Update: Study Comparing Efficacy of Doxorubicin With Trabectedin Followed by Trabectedin Versus Doxorubicine in Patients With Leiomyosarcoma [Phase 3]
Phase 3 trial comparing doxorubicin with trabectedin followed by trabectedin versus doxorubicine in leiomyosarcoma completed.
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CLINICAL_TRIALS trial_result · 2020-05-12Clinical Trial Update: Nivolumab Alone or in Combination With Ipilimumab in Treating Patients With Advanced Uterine Leiomyosarcoma [Phase 2]
Phase 2 clinical trial evaluating nivolumab alone or in combination with ipilimumab in patients with advanced or unresectable uterine leiomy…
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CLINICAL_TRIALS trial_result · 2020-04-06Clinical Trial Update: Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery [Phase 3]
Phase 3 trial investigating gemcitabine hydrochloride and docetaxel followed by doxorubicin hydrochloride or observation in high-risk uterin…
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CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: Sunitinib in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus [Phase 2]
Phase 2 trial evaluating sunitinib in patients with recurrent or persistent uterine leiomyosarcoma and recurrent uterine sarcoma has complet…
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CLINICAL_TRIALS trial_result · 2018-10-11Clinical Trial Update: Letrozole Versus Observation in Patients With Newly Diagnosed Uterine Leiomyosarcoma [Phase 2]
Phase 2 trial comparing letrozole to observation in newly diagnosed uterine leiomyosarcoma; trial terminated with results posted.
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CLINICAL_TRIALS trial_result · 2017-12-12Clinical Trial Update: Trabectedin in Treating Patients With Advanced, Persistent, or Recurrent Leiomyosarcoma of the Uterus [Phase 2]
Phase 2 trial results for trabectedin in patients with advanced, persistent, or recurrent uterine leiomyosarcoma have been posted. The study…
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CLINICAL_TRIALS trial_result · 2017-12-06Clinical Trial Update: Activity of Trabectedin or Gemcitabine + Docetaxel in Uterine Leiomyosarcoma [Phase 2]
Phase 2 trial evaluating activity of trabectedin versus gemcitabine plus docetaxel in uterine leiomyosarcoma has completed.
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CLINICAL_TRIALS trial_result · 2017-02-14Clinical Trial Update: Multicenter Trial With PegLiposomal Doxorubicin and Carboplatin Combination Chemotherapy in Gynecological Sarcomas and Mixed Epithelial-Mesenchymal Tumors [Phase 2]
Phase 2 multicenter study evaluating pegylated liposomal doxorubicin plus carboplatin in gynecologic mesenchymal tumors, including carcinosa…
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CLINICAL_TRIALS trial_result · 2017-01-26Clinical Trial Update: Study of Doxorubicin and Trabectedin in First Line Treatment on Patients With Metastatic Leiomyosarcoma [Phase 2]
Phase 2 trial evaluating first-line Doxorubicin and Trabectedin in metastatic leiomyosarcoma has completed; results are not detailed in this…
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CLINICAL_TRIALS trial_result · 2016-08-30Clinical Trial Update: Gemcitabine With or Without Docetaxel as Second-Line Therapy in Treating Patients With Metastatic or Relapsed, Unresectable Uterine or Soft Tissue Leiomyosarcoma [Phase 2]
Phase 2 trial evaluating gemcitabine with or without docetaxel as second-line therapy for metastatic or relapsed, unresectable uterine or so…
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CLINICAL_TRIALS trial_result · 2015-12-22Clinical Trial Update: Adjuvant Docetaxel Plus Gemcitabine in Patients With Completely Resected Leiomyosarcoma (LMS) of the Uterus [NA]
This completed trial evaluated adjuvant docetaxel plus gemcitabine in patients with completely resected uterine leiomyosarcoma.
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CLINICAL_TRIALS withdrawal · 2015-11-18Clinical Trial Update: Pazopanib for Treating Uterine Leiomyosarcoma [Phase 2]
The Phase 2 clinical trial of pazopanib for treating uterine leiomyosarcoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-07-30Clinical Trial Update: AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma [Phase 2]
A Phase 2 trial evaluating saracatinib (AZD0530) in adults with recurrent, locally advanced, or metastatic soft tissue sarcoma has completed…
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CLINICAL_TRIALS trial_result · 2014-11-21Clinical Trial Update: Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma [Phase 2]
Phase 2 trial evaluating Ziv-aflibercept in locally advanced, unresectable, or metastatic gynecologic soft tissue sarcoma has completed with…