Urothelial Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: A Study to Evaluate Safety, Efficacy of FF-10832 in Combo With Pembrolizumab in Urothelial & Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update evaluating the safety and efficacy of FF-10832 in combination with pembrolizumab for advanced urothelial carci…
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CLINICAL_TRIALS other · 2025-09-04Clinical Trial Update: A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma
The trial compares neoadjuvant chemotherapy against upfront radical surgery for upper tract urothelial carcinoma and is currently active but…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab [Phase 2]
Phase 2 clinical trial update on Stage II-IIIa urothelial carcinoma evaluating pre-operative nivolumab with or without relatlimab. Recruitme…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Ivonescimab in the Treatment of Multiple Advanced Tumors [Phase 2]
An update indicating Ivonescimab is being studied in a Phase 2 trial for multiple advanced tumors and is currently recruiting. The trial cov…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Trilaciclib, a CDK 4/6 Inhibitor, in Patients With Advanced/Metastatic Bladder Cancer Receiving Chemotherapy Then Avelumab [Phase 2]
This is a Phase 2 trial evaluating trilaciclib in combination with chemotherapy followed by avelumab for advanced/metastatic urothelial carc…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: A Study of ADRX-0706 in Select Advanced Solid Tumors [Phase 1]
Phase 1 study of ADRX-0706 in select advanced solid tumors is active/not recruiting, evaluating the investigational agent in triple-negative…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 clinical trial update on cabozantinib alone or with atezolizumab for locally advanced or metastatic solid tumors; the study lists mu…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Immunotherapy With or Without Radiation Therapy for Metastatic Urothelial Cancer [Phase 2]
A Phase 2 trial of immunotherapy with or without radiation therapy for metastatic urothelial carcinoma, including platinum-resistant disease…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies [Phase 1]
Phase 1 dose-escalation and expansion study of intratumoral mRNA-2752 in advanced malignancies has completed, with expansion cohorts in seve…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Clinical Trial of AM80 in Combination With Gemcitabine, Cisplatin, and Nivolumab in Patients With Urothelial Carcinoma [Phase 2]
A Phase 2 clinical trial is evaluating AM80 in combination with gemcitabine, cisplatin, and nivolumab for urothelial carcinoma; recruitment …
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Safety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory Cancer [Phase 1]
Phase 1 safety study evaluating enoblituzumab (MGA271) in combination with pembrolizumab or MGA012 in patients with refractory cancers. Resu…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Study to Evaluate Adverse Events and Change in Disease Activity When Intravenously (IV) Infused Livmoniplimab is Used in Combination With IV Infused Budigalimab in Adult Participants With Urothelial Carcinoma (UC) [Phase 2]
Phase 2 clinical trial evaluating adverse events and change in disease activity when livmoniplimab is used in combination with budigalimab i…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors [Phase 1]
Phase 1, first-in-human dose-finding and expansion study of XmAb808 in combination with pembrolizumab in advanced solid tumors; the trial ha…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Research of Double-positive Circulating Cells (Tumor Marker / CD45+) in Several Types of Metastatic Cancers [NA]
A multi-cancer prospective study evaluating double-positive circulating cells (CD45+ tumor marker) in several types of metastatic cancers; r…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: A Study of Evorpacept (ALX148) With Enfortumab Vedotin for Subjects With Urothelial Carcinoma (ASPEN-07) [Phase 1]
Phase 1 study ASPEN-07 evaluating Evorpacept (ALX148) with Enfortumab Vedotin for urothelial carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: HER2 and LA/mUC: A Multi-country Chart Review Cohort Study
A multi-country chart review cohort study evaluating HER2-directed therapy in locally advanced or metastatic urothelial carcinoma has comple…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma [Phase 2]
A Phase 2 trial evaluating gemcitabine and carboplatin after progression on enfortumab vedotin and pembrolizumab in advanced/metastatic urot…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours [Phase 1, Phase 2]
NuCana plc announced termination of a Phase 1/2 trial evaluating NUC-3373 in combination with other agents for patients with advanced solid …
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Neurological Function in Patients With Locally Advanced or Metastatic Urothelial Carcinoma Treated With Enfortumab Vedotin-Based Therapy
A clinical trial update describes neurological function in patients with locally advanced or metastatic urothelial carcinoma treated with en…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: A Phase III Study of SHR-A2102 Versus Investigator-selected Therapy in Advanced Urothelial Carcinoma [Phase 3]
This clinical trial update indicates a Phase III study (SHR-A2102 vs investigator-selected therapy) for advanced urothelial carcinoma is cur…
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EMA approval · 2025-07-16EMA Authorised: Javlor (vinflunine) — Pierre Fabre Medicament
The European Medicines Agency authorised Javlor (vinflunine) from Pierre Fabre Medicament for transitional cell carcinoma of the urothelium …
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: A Biomarker Study to Predict Treatment Outcomes of Enfortumab Vedotin in Advanced Urothelial Carcinoma
A biomarker study to predict treatment outcomes of enfortumab vedotin in advanced urothelial carcinoma; the trial is currently active but no…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors [Phase 1]
This Phase 1 trial reports on the safety, tolerability, pharmacokinetics, and pharmacodynamics of INCB099280 in participants with advanced s…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Focused Ultrasound Ablation and PD-1 Antibody Blockade in Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating the combination of focused ultrasound ablation with PD-1 antibody blockade in advanced solid tumors has been termin…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: INO-5401 + INO-9012 in Combination With Atezolizumab in Locally Advanced Unresectable or Metastatic/Recurrent Urothelial Carcinoma [Phase 1, Phase 2]
This clinical trial update reports the completion of a Phase 1/2 study evaluating the combination of INO-5401 and INO-9012 with atezolizumab…