Urothelial Carcinoma of the Ureter
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating whether circulating tumor DNA in blood can guide the use of immunotherapy after surgical removal of urot…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy Treatment, Avelumab, in Patients With Metastatic Urothelial Cancer, MAIN-CAV Study [Phase 3]
A Phase 3 trial (MAIN-CAV) is evaluating the addition of cabozantinib to the immunotherapy drug avelumab for metastatic urothelial cancer, w…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer [Phase 3]
Phase 3 trial status update for pembrolizumab after surgery in localized muscle-invasive bladder cancer and locally advanced urothelial carc…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Neoadjuvant Chemotherapy Before Surgery vs Surgery Alone for UTUC: A Randomized Trial [Phase 2]
This is a Phase 2 randomized trial comparing neoadjuvant chemotherapy before surgery to surgery alone for upper tract urothelial carcinoma. …
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Immune Checkpoint Inhibitors With or Without Propranolol Hydrochloride In Patients With Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating immune checkpoint inhibitors with or without propranolol hydrochloride in urothelial carcinoma; the study is curren…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial [Phase 4]
Phase 4 CAST-AI is a clinical trial evaluating enfortumab vedotin in combination with pembrolizumab with cystectomy and/or ureterectomy for …
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Bladder EpiCheck European Haematuria Study
Nucleix's urine-based EpiCheck test is being evaluated in a European haematuria study and is currently recruiting to assess detection of uro…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of Bladder Cancers [Phase 2]
Phase 2 trial evaluating therapeutic plasma exchange in combination with enfortumab vedotin and pembrolizumab for metastatic bladder urothel…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Clinical Trial of AM80 in Combination With Gemcitabine, Cisplatin, and Nivolumab in Patients With Urothelial Carcinoma [Phase 2]
A Phase 2 clinical trial is evaluating AM80 in combination with gemcitabine, cisplatin, and nivolumab for urothelial carcinoma; recruitment …
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Gemcitabine Versus Water Irrigation in Upper Tract Urothelial Carcinoma [Phase 3]
A Phase 3 clinical trial is currently recruiting to compare gemcitabine against water irrigation for upper tract urothelial carcinoma, inclu…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto
A registry update for the uTRACT Jelmyto Registry, documenting UTUC patients treated with Jelmyto and the study status as Recruiting.
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Radiotherapy Combined with Systemic Therapy Versus Systemic Therapy for Oligometastatic UTUCs [NA]
A recruiting clinical trial from Peking University First Hospital compares radiotherapy added to systemic therapy versus systemic therapy al…
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CLINICAL_TRIALS research · 2024-07-05Clinical Trial Update: Performance Evaluation of Urine DNA Methylation Testing for the Detection of Urothelial Carcinoma in Patients With Hematuria
This clinical trial evaluates a urine DNA methylation test for detecting urothelial carcinoma in patients with hematuria.
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CLINICAL_TRIALS research · 2009-10-14Clinical Trial Update: A Clinical Study of the Living Renal Transplantation With Restored Kidneys Between Family Members [NA]
This document provides a Clinical Trial Update on a living renal transplantation study involving restored kidneys exchanged between family m…