Urothelial Carcinoma of the Renal Pelvis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating whether circulating tumor DNA in blood can guide the use of immunotherapy after surgical removal of urot…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy Treatment, Avelumab, in Patients With Metastatic Urothelial Cancer, MAIN-CAV Study [Phase 3]
A Phase 3 trial (MAIN-CAV) is evaluating the addition of cabozantinib to the immunotherapy drug avelumab for metastatic urothelial cancer, w…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer [Phase 3]
Phase 3 trial status update for pembrolizumab after surgery in localized muscle-invasive bladder cancer and locally advanced urothelial carc…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy [Phase 3]
Phase 3 trial update evaluating the optimal duration of immune checkpoint therapy for locally advanced and metastatic urothelial carcinoma; …
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Immune Checkpoint Inhibitors With or Without Propranolol Hydrochloride In Patients With Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating immune checkpoint inhibitors with or without propranolol hydrochloride in urothelial carcinoma; the study is curren…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial [Phase 4]
Phase 4 CAST-AI is a clinical trial evaluating enfortumab vedotin in combination with pembrolizumab with cystectomy and/or ureterectomy for …
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Bladder EpiCheck European Haematuria Study
Nucleix's urine-based EpiCheck test is being evaluated in a European haematuria study and is currently recruiting to assess detection of uro…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of Bladder Cancers [Phase 2]
Phase 2 trial evaluating therapeutic plasma exchange in combination with enfortumab vedotin and pembrolizumab for metastatic bladder urothel…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Low-Dose-Rate Brachytherapy Combined With Immune Checkpoint Inhibition in Cancer [Phase 1]
Phase 1 clinical trial evaluating the combination of low-dose-rate brachytherapy with immune checkpoint inhibitors in cancer; the study incl…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Clinical Trial of AM80 in Combination With Gemcitabine, Cisplatin, and Nivolumab in Patients With Urothelial Carcinoma [Phase 2]
A Phase 2 clinical trial is evaluating AM80 in combination with gemcitabine, cisplatin, and nivolumab for urothelial carcinoma; recruitment …
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Gemcitabine Versus Water Irrigation in Upper Tract Urothelial Carcinoma [Phase 3]
A Phase 3 clinical trial is currently recruiting to compare gemcitabine against water irrigation for upper tract urothelial carcinoma, inclu…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto
A registry update for the uTRACT Jelmyto Registry, documenting UTUC patients treated with Jelmyto and the study status as Recruiting.
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Named Patient Program for Mitomycin for Pyelocalyceal Solution
This clinical-trials.gov update describes a named patient program for mitomycin-C delivered as a pyelocalyceal solution to treat urothelial …
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CLINICAL_TRIALS trial_result · 2024-12-30Clinical Trial Update: Testing the Addition of an Anti-Cancer Immunotherapy Drug, Avelumab, to Gemcitabine and Carboplatin Chemotherapy Prior to Surgery in Muscle Invasive Urinary Tract Cancer vs. Surgery Alone in Patients Who Are Not Able to Receive Cisplatin Therapy (SWOG GAP TRIAL) [Phase 2]
SWOG's Phase 2 trial evaluating adding avelumab to gemcitabine and carboplatin before surgery in cisplatin-ineligible muscle-invasive urinar…
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Radiotherapy Combined with Systemic Therapy Versus Systemic Therapy for Oligometastatic UTUCs [NA]
A recruiting clinical trial from Peking University First Hospital compares radiotherapy added to systemic therapy versus systemic therapy al…
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CLINICAL_TRIALS research · 2024-07-05Clinical Trial Update: Performance Evaluation of Urine DNA Methylation Testing for the Detection of Urothelial Carcinoma in Patients With Hematuria
This clinical trial evaluates a urine DNA methylation test for detecting urothelial carcinoma in patients with hematuria.
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: A Study of ALT-801 in Combination With Cisplatin and Gemcitabine in Muscle Invasive or Metastatic Urothelial Cancer [Phase 1, Phase 2]
This update reports results from a Phase 1/2 trial evaluating ALT-801 in combination with cisplatin and gemcitabine in patients with muscle-…
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CLINICAL_TRIALS trial_result · 2021-12-17Clinical Trial Update: A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer [Phase 2]
Phase 2 study of enfortumab vedotin in locally advanced or metastatic urothelial cancer has been completed and results have been posted. The…
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CLINICAL_TRIALS trial_result · 2016-01-25Clinical Trial Update: Sunitinib in Treating Patients With Progressive Metastatic Transitional Cell Cancer of the Urothelium [Phase 2]
This updates the completion of a Phase 2 trial of sunitinib in patients with progressive metastatic urothelial cancer (transitional cell car…
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CLINICAL_TRIALS trial_result · 2015-09-03Clinical Trial Update: Sorafenib in Treating Patients With Advanced or Metastatic Cancer of the Urinary Tract [Phase 2]
Phase 2 trial evaluating sorafenib in advanced or metastatic urothelial cancers of the urinary tract (including bladder, renal pelvis, and u…
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CLINICAL_TRIALS trial_result · 2013-06-05Clinical Trial Update: Gefitinib Plus Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Bladder Cancer [Phase 2]
Phase 2 trial update evaluating gefitinib in combination chemotherapy for locally advanced or metastatic bladder cancer (urothelial carcinom…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Arsenic Trioxide in Treating Patients With Urothelial Cancer [Phase 2]
A Phase 2 clinical trial evaluating arsenic trioxide in patients with recurrent urothelial cancers (including bladder, renal pelvis, ureter,…
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CLINICAL_TRIALS trial_result · 2013-05-27Clinical Trial Update: S0219, Combination Chemotherapy Followed By Observation or Surgery in Patients With Stage II or Stage III Cancer of the Urothelium [Phase 2]
A Phase 2 SWOG trial evaluating combination chemotherapy followed by observation or surgery in patients with stage II–III urothelial cancer …
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CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: Trastuzumab in Treating Patients With Previously Treated, Locally Advanced, or Metastatic Cancer of the Urothelium [Phase 2]
Phase 2 trial evaluating trastuzumab for previously treated, locally advanced or metastatic urothelial cancer was terminated.
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CLINICAL_TRIALS trial_result · 2013-03-21Clinical Trial Update: Pazopanib in Treating Patients With Metastatic Urothelial Cancer [Phase 2]
A Phase 2 trial of pazopanib in metastatic urothelial cancer has completed and results have been posted.