Urothelial Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-12-29Clinical Trial Update: A Study of Epacadostat (INCB024360) in Combination With Durvalumab (MEDI4736) in Subjects With Selected Advanced Solid Tumors (ECHO-203) [Phase 1, Phase 2]
Phase 1/2 study of epacadostat plus durvalumab in selected advanced solid tumors completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-12-19Clinical Trial Update: Phase II Study of TKI258 in Advanced Urothelial Carcinoma [Phase 2]
Phase II study update of TKI258 in advanced urothelial carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: A Study Of Avelumab In Patients With Locally Advanced Or Metastatic Urothelial Cancer (JAVELIN Bladder 100) [Phase 3]
Phase 3 trial update for avelumab in locally advanced or metastatic urothelial cancer (JAVELIN Bladder 100) with results posted.
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CLINICAL_TRIALS trial_result · 2020-10-12Clinical Trial Update: Afatinib Monotherapy in Patients With ERBB-deregulated Metastatic Urothelial Tract Carcinoma After Failure of Platinum Based Chemotherapy [Phase 2]
Phase 2 trial evaluating afatinib as monotherapy in ERBB-deregulated metastatic urothelial tract carcinoma after platinum failure has comple…
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CLINICAL_TRIALS trial_result · 2020-09-10Clinical Trial Update: Erlotinib Hydrochloride in Treating Participants With Muscle Invasive or Recurrent Urothelial Cancer [Phase 2]
Phase 2 clinical trial evaluating erlotinib hydrochloride in patients with muscle-invasive or recurrent urothelial cancer has completed, wit…
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CLINICAL_TRIALS trial_result · 2020-07-09Clinical Trial Update: A Study Combining Eribulin Mesylate With Avelumab in Cisplatin Ineligible Metastatic Urothelial Cell Cancer Patients [Phase 1]
Phase 1 trial evaluating eribulin mesylate with avelumab in cisplatin-ineligible metastatic urothelial cell cancer; study terminated with re…
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CLINICAL_TRIALS trial_result · 2020-04-15Clinical Trial Update: Study of Regorafenib for Urothelial Cancer Following Chemotherapy (UAB 1477) [Phase 2]
Phase 2 study of regorafenib for urothelial cancer completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: Nab-Paclitaxel to Paclitaxel in Advanced Urothelial Cancer Progressing on or After Platinum Containing Regimen. [Phase 2]
Phase 2 trial comparing Nab-Paclitaxel to Paclitaxel in advanced urothelial cancer progressing after platinum therapy has completed with pos…
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CLINICAL_TRIALS trial_result · 2019-12-19Clinical Trial Update: Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancers [Phase 1, Phase 2]
Phase 1/2 trial evaluating MK-3475 (pembrolizumab) in combination with INCB024360 in various selected cancers; study completed with results …
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CLINICAL_TRIALS trial_result · 2019-08-09Clinical Trial Update: A Study Evaluating Chemotherapy With Fractionated Cisplatin/Gemcitabine Versus Carboplatin/Gemcitabine in the Treatment of Advanced or Metastatic Urothelial Cancer With Impaired Renal Function. [Phase 2, Phase 3]
A phase 2/3 trial comparing fractionated cisplatin/gemcitabine versus carboplatin/gemcitabine in advanced or metastatic urothelial cancer wi…
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CLINICAL_TRIALS trial_result · 2019-07-05Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Participants With Advanced Urothelial Cancer (MK-3475-052/KEYNOTE-052) [Phase 2]
Phase 2 study of pembrolizumab in advanced urothelial cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-11-23Clinical Trial Update: Expanded Phase I Pazopanib and Everolimus in Advanced Solid Tumors and Previously Treated Advanced Urothelial Cancer [Phase 1]
Phase I study update of pazopanib and everolimus in advanced solid tumors and previously treated advanced urothelial cancer has completed (r…
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CLINICAL_TRIALS trial_result · 2018-11-19Clinical Trial Update: Paclitaxel and TAK-228 in Urothelial Carcinoma [Phase 2]
Phase 2 clinical trial update of paclitaxel and TAK-228 in metastatic urothelial cancer.
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CLINICAL_TRIALS trial_result · 2018-08-22Clinical Trial Update: SU011248 for Platinum-Refractory Urothelial Cancer Evaluation Trial [Phase 2]
Phase 2 trial evaluating SU011248 for platinum-refractory urothelial/bladder cancer has completed.
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: Genetic Determinants of Response to Neoadjuvant Cisplatin-based Chemotherapy in Urothelial Cancer
This clinical trial update reports on genetic determinants of response to neoadjuvant cisplatin-based chemotherapy in urothelial cancer.
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FDA approval · 2018-04-30FDA Approved: DOCETAXEL — Original Application (Mylan Institutional LLC)
The FDA approved Mylan Institutional LLC's original application for a generic docetaxel anhydrous product (ANDA208859).
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CLINICAL_TRIALS trial_result · 2018-01-30Clinical Trial Update: Ganetespib and Ziv-Aflibercept in Refractory Gastrointestinal Carcinomas, Non-Squamous Non-Small Cell Lung Carcinomas, Urothelial Carcinomas, and Sarcomas [Phase 1]
Phase 1 study of ganetespib with ziv-aflibercept in refractory gastrointestinal cancer, non-small cell lung cancer (non-squamous), urothelia…
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CLINICAL_TRIALS trial_result · 2017-11-22Clinical Trial Update: Intravenous BI 6727 (Volasertib) in 2nd Line Treatment of Urothelial Cancer [Phase 2]
Phase 2 trial update of intravenous Volasertib (BI-6727) in second-line urothelial cancer; results have been posted following study completi…
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CLINICAL_TRIALS trial_result · 2017-08-31Clinical Trial Update: A Study of Pembrolizumab (MK-3475) Versus Paclitaxel, Docetaxel, or Vinflunine for Participants With Advanced Urothelial Cancer (MK-3475-045/KEYNOTE-045) [Phase 3]
Phase 3 trial comparing pembrolizumab to chemotherapy for advanced urothelial cancer has completed with posted results in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: A Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer (Cohort 1) [Phase 2]
Phase 2 trial update for atezolizumab in locally advanced or metastatic urothelial/bladder cancer completed with posted results.
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Study of Cetuximab With and Without Weekly Paclitaxel for Patients With Previously Treated Advanced Urothelial Cancer [Phase 2]
This update reports Phase 2 results for cetuximab with or without weekly paclitaxel in patients with previously treated advanced urothelial …
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CLINICAL_TRIALS withdrawal · 2016-12-07Clinical Trial Update: A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patients [Phase 1, Phase 2]
This Phase 1/Phase 2 trial evaluating CDX-1401 in combination with Poly-ICLC and pembrolizumab for previously treated advanced solid tumors …
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CLINICAL_TRIALS trial_result · 2016-06-21Clinical Trial Update: The Efficacy of RAD 001 as Second Line Therapy in Patients With Transitional Cell Carcinoma TCC of the Urothelium [Phase 2]
This Phase 2 trial evaluates RAD 001 (everolimus) as second-line therapy for urothelial cancer (transitional cell carcinoma of the urotheliu…
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CLINICAL_TRIALS trial_result · 2016-05-05Clinical Trial Update: Larotaxel + Cisplatin Versus Gemcitabine + Cisplatin in First Line Treatment of Locally Advanced/Metastatic Urothelial Tract or Bladder Cancer [Phase 3]
A Phase 3 randomized trial compares larotaxel plus cisplatin versus gemcitabine plus cisplatin as first-line therapy for locally advanced or…
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CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: Gemzar, Cisp, Sunitinib Urothelial Ca [Phase 2]
Phase 2 trial update reporting results for a combination of gemcitabine, cisplatin, and sunitinib in urothelial cancer; the study has comple…