Urothelial Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer [Phase 3]
Phase 3 results from a trial comparing enfortumab vedotin plus pembrolizumab versus chemotherapy in untreated locally advanced or metastatic…
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CLINICAL_TRIALS withdrawal · 2024-09-26Clinical Trial Update: A Study of MFA-370 in Patients with Metastatic Urothelial Cancer [Phase 1, Phase 2]
A clinical trial evaluating MFA-370 in metastatic urothelial cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Gemcitabine + Carboplatin + Nivolumab Versus Gemcitabine + Oxaliplatin + Nivolumab in Cisplatin-ineligible Patients With Metastatic Urothelial Cancer [Phase 2]
Phase 2 trial comparing gemcitabine + carboplatin + nivolumab versus gemcitabine + oxaliplatin + nivolumab in cisplatin-ineligible patients …
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CLINICAL_TRIALS trial_result · 2024-04-18Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Bintrafusp Alfa (M7824) Monotherapy in Metastatic or Locally Advanced Urothelial Cancer [Phase 1]
Phase 1 trial evaluating bintrafusp alfa (M7824) monotherapy in metastatic or locally advanced urothelial cancer has been terminated with re…
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF) [Phase 2]
Phase 2 study evaluating avelumab in combination with axitinib for non-small cell lung cancer or urothelial cancer has been terminated with …
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CLINICAL_TRIALS trial_result · 2024-02-15Clinical Trial Update: A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations [Phase 2]
A Phase 2 clinical trial update shows results for trastuzumab deruxtecan (Enhertu) in solid tumors with HER2 activating mutations; the study…
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: Avelumab as Single Agent in Metastatic or Locally Advanced Urothelial Cancer in Patients Unfit for Cisplatin. The ARIES Study [Phase 2]
Phase 2 trial evaluating avelumab as a single agent in metastatic or locally advanced urothelial cancer in patients unfit for cisplatin has …
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Trial of Olaparib in Patients With Metastatic Urothelial Cancer Harboring DNA Damage Response Gene Alterations [Phase 2]
Phase 2 trial evaluating olaparib in metastatic urothelial cancer patients with DNA damage response gene alterations has completed; results …
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CLINICAL_TRIALS trial_result · 2023-10-18Clinical Trial Update: Avelumab Plus Carboplatin-gemcitabine in Urothelial Carcinoma [Phase 2]
Phase 2 trial evaluating avelumab plus carboplatin-gemcitabine in metastatic urothelial cancer has completed.
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer [Phase 2]
This update reports efficacy and safety data from a Phase 2 trial of Erdafitinib in participants with urothelial cancer.
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: A Study to Evaluate Enfortumab Vedotin (ASG-22CE) in Chinese Participants With Locally Advanced or Metastatic Urothelial Cancer Who Previously Received Platinum-containing Chemotherapy and Programmed Cell Death Protein-1 ( PD 1) / (Programmed Death Ligand-1 (PD-L1) Inhibitor Therapy [Phase 2]
Phase 2 trial results for enfortumab vedotin in Chinese participants with locally advanced or metastatic urothelial cancer who previously re…
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CLINICAL_TRIALS trial_result · 2023-08-08Clinical Trial Update: Gemcitabine for the Prevention of Intravesical Recurrence of Urothelial Cancer in Patients With Upper Urinary Tract Urothelial Cancer Undergoing Radical Nephroureterectomy, GEMINI Study [Phase 2]
Phase 2 trial evaluating gemcitabine to prevent intravesical recurrence of urothelial cancer in patients with upper tract urothelial cancer …
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CLINICAL_TRIALS trial_result · 2023-08-03Clinical Trial Update: Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene [Phase 1, Phase 2]
Phase 1/2 clinical trial studying A166 in patients with various HER2-expressing or HER2-amplified cancers has completed.
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CLINICAL_TRIALS trial_result · 2023-02-13Clinical Trial Update: Study of Disitamab Vedotin Combined With Gemcitabine in Neoadjuvant Treatment of Urothelial Carcinoma [Phase 4]
A Phase 4 clinical trial is evaluating disitamab vedotin in combination with gemcitabine as neoadjuvant therapy for urothelial carcinoma und…
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CLINICAL_TRIALS trial_result · 2023-01-06Clinical Trial Update: Open-Label, Dose-Escalation Study of Pemigatinib in Subjects With Advanced Malignancies - (FIGHT-101) [Phase 1, Phase 2]
Open-label, dose-escalation study of pemigatinib in advanced malignancies (FIGHT-101) completed; results posted.
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CLINICAL_TRIALS trial_result · 2022-12-12Clinical Trial Update: GEN1029 (HexaBody®-DR5/DR5) Safety Trial in Patients With Malignant Solid Tumors [Phase 1, Phase 2]
Phase 1/2 safety trial of GEN1029 (HexaBody-DR5/DR5) in malignant solid tumors (termina ted; results posted in 2022).
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CLINICAL_TRIALS trial_result · 2022-10-05Clinical Trial Update: Paclitaxel and Pembrolizumab in Treating Patients With Refractory Metastatic Urothelial Cancer [Phase 2]
Phase 2 trial evaluating paclitaxel and pembrolizumab in refractory metastatic urothelial cancer (transitional cell carcinoma) has completed…
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CLINICAL_TRIALS trial_result · 2022-09-10Clinical Trial Update: Vopratelimab and a CTLA-4 Inhibitor in PD-1/PD-L1 Inhibitor Experienced Subjects With NSCLC or Urothelial Cancer [Phase 2]
Phase 2 trial updating Vopratelimab in combination with a CTLA-4 inhibitor in patients previously treated with PD-1/PD-L1 inhibitors (NSCLC …
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CLINICAL_TRIALS trial_result · 2022-06-23Clinical Trial Update: Safety And Efficacy Study Of Avelumab Plus Chemotherapy With Or Without Other Anti-Cancer Immunotherapy Agents In Patients With Advanced Malignancies [Phase 1, Phase 2]
Phase 1/2 trial evaluating avelumab plus chemotherapy with or without other anti-cancer immunotherapy agents in advanced malignancies (termi…
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CLINICAL_TRIALS trial_result · 2022-05-10Clinical Trial Update: A Study of INCMGA00012 in Participants With Selected Solid Tumors (POD1UM-203) [Phase 2]
Phase 2 clinical trial update for INCMGA00012 in selected solid tumors, with completed status and results posted.
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CLINICAL_TRIALS trial_result · 2022-03-29Clinical Trial Update: T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positive [Phase 1, Phase 2]
Phase 1/2 trial update on a T cell receptor therapy targeting MAGE-A3 in HLA-DP0401 positive metastatic cancer; study completed with posted …
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CLINICAL_TRIALS trial_result · 2021-12-14Clinical Trial Update: A Study of MRG002 in the Treatment of HER2-positive Unresectable Locally Advanced or Metastatic Urothelium Cancer [Phase 2]
Phase 2 trial update for MRG002 in HER2-positive unresectable locally advanced or metastatic urothelial cancer.
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CLINICAL_TRIALS trial_result · 2021-09-30Clinical Trial Update: Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors [Phase 1]
Phase 1 study results for INCB001158, an arginase inhibitor, as a single agent and in combination with immune checkpoint therapy, in patient…
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CLINICAL_TRIALS trial_result · 2021-08-24Clinical Trial Update: A Study to Evaluate Enfortumab Vedotin Versus (vs) Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer (EV-301) [Phase 3]
Phase 3 EV-301 trial comparing enfortumab vedotin to standard chemotherapy in previously treated locally advanced or metastatic urothelial c…
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CLINICAL_TRIALS trial_result · 2021-08-20Clinical Trial Update: Biomarkers in Urothelial Cancer Patients Treated With Pembrolizumab [Phase 2]
Phase 2 trial update examining biomarkers in urothelial cancer patients treated with pembrolizumab.