Urethral Cancer

• CLINICAL_TRIALS trial_result · 2026-03-24
  Clinical Trial Update: A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer [Phase 1, Phase 2]

  A study of Enfortumab Vedotin, alone or with other therapies, for urothelial cancers has been terminated.

• CLINICAL_TRIALS trial_result · 2025-04-25
  Clinical Trial Update: Afatinib in Advanced Refractory Urothelial Cancer [Phase 2]

  Phase 2 trial of afatinib in advanced refractory urothelial cancer was terminated, with results posted.

• CLINICAL_TRIALS trial_result · 2024-07-03
  Clinical Trial Update: Atezolizumab and CYT107 in Treating Participants With Locally Advanced, Inoperable, or Metastatic Urothelial Carcinoma [Phase 2]

  Phase 2 trial results evaluate the combination of atezolizumab and CYT107 in participants with locally advanced, inoperable, or metastatic u…

• CLINICAL_TRIALS trial_result · 2024-05-14
  Clinical Trial Update: A Study of ALT-801 in Combination With Cisplatin and Gemcitabine in Muscle Invasive or Metastatic Urothelial Cancer [Phase 1, Phase 2]

  This update reports results from a Phase 1/2 trial evaluating ALT-801 in combination with cisplatin and gemcitabine in patients with muscle-…

• CLINICAL_TRIALS trial_result · 2023-06-22
  Clinical Trial Update: Two-Drug Combination Chemotherapy Compared With Four-Drug Combination Chemotherapy in Treating Patients With Advanced Cancer of the Urothelium [Phase 3]

  Phase 3 trial comparing two-drug vs four-drug chemotherapy regimens in advanced urothelial cancer (bladder cancer and related urothelial can…

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• CLINICAL_TRIALS trial_result · 2023-06-22
  Clinical Trial Update: Combination Chemotherapy in Treating Patients With Advanced Cancer of the Urothelium and Decreased Kidney Function [Phase 2]

  A Phase 2 clinical trial evaluating combination chemotherapy for advanced urothelial cancer with decreased kidney function has completed.

• CLINICAL_TRIALS trial_result · 2023-06-22
  Clinical Trial Update: Piritrexim in Treating Patients With Advanced Cancer of the Urinary Tract [Phase 2]

  Phase 2 clinical trial evaluating piritrexim in advanced urinary tract cancers has completed enrollment.

• CLINICAL_TRIALS trial_result · 2023-06-18
  Clinical Trial Update: Docetaxel and Gemcitabine in Treating Patients With Progressive Regional or Metastatic Bladder Cancer [Phase 2]

  Phase 2 trial evaluating docetaxel and gemcitabine in progressive regional or metastatic bladder cancer and related transitional cell cancer…

• CLINICAL_TRIALS trial_result · 2023-06-15
  Clinical Trial Update: Combination Chemotherapy in Treating Patients With Bladder Cancer [Phase 3]

  A Phase 3 clinical trial update on combination chemotherapy for bladder cancer and urethral cancer has completed.

• CLINICAL_TRIALS trial_result · 2021-02-21
  Clinical Trial Update: Surgery Plus Combination Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Urinary Tract [Phase 2]

  Phase 2 trial evaluating surgery plus combination chemotherapy and radiation therapy for cancer of the urinary tract (bladder cancer and rel…

• CLINICAL_TRIALS trial_result · 2020-09-10
  Clinical Trial Update: Erlotinib Hydrochloride in Treating Participants With Muscle Invasive or Recurrent Urothelial Cancer [Phase 2]

  Phase 2 clinical trial evaluating erlotinib hydrochloride in patients with muscle-invasive or recurrent urothelial cancer has completed, wit…

• CLINICAL_TRIALS trial_result · 2019-12-16
  Clinical Trial Update: Gemcitabine Hydrochloride and Eribulin Mesylate in Treating Patients With Bladder Cancer That is Advanced or Cannot Be Removed by Surgery [Phase 2]

  Phase 2 clinical trial evaluating gemcitabine hydrochloride and eribulin mesylate in advanced or unresectable bladder, ureter, and urethral …

• CLINICAL_TRIALS trial_result · 2019-05-16
  Clinical Trial Update: Carboplatin and Gemcitabine Hydrochloride With or Without Vandetanib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Urinary Tract Cancer [Phase 2]

  Phase 2 trial evaluating carboplatin and gemcitabine with or without vandetanib as first-line therapy for locally advanced or metastatic uri…

• CLINICAL_TRIALS trial_result · 2017-09-28
  Clinical Trial Update: Four Cycles Versus Six Cycles of Cisplatin-based Chemotherapy in Metastatic Urothelial Carcinoma [Phase 3]

  A Phase 3 trial comparing four vs six cycles of cisplatin-based chemotherapy in metastatic urothelial carcinoma is ongoing/unknown status.

• CLINICAL_TRIALS trial_result · 2016-02-24
  Clinical Trial Update: S0028, Gemcitabine and Paclitaxel in Treating Patients With Advanced or Recurrent Cancer of the Urinary Tract [Phase 2]

  Phase 2 SWOG trial of gemcitabine and paclitaxel in advanced or recurrent urinary tract cancers (bladder cancer, transitional cell carcinoma…

• CLINICAL_TRIALS trial_result · 2015-05-14
  Clinical Trial Update: Short-Term Low-Dose Interferon Alfa in Treating Patients With Cancer of the Urothelium [Phase 1]

  A Phase 1 trial from MD Anderson Cancer Center evaluated short-term low-dose interferon alfa in patients with urothelial cancers (bladder an…

• CLINICAL_TRIALS trial_result · 2015-05-06
  Clinical Trial Update: Videoscopic Versus Open Inguinal Lymphadenectomy for Cancer [NA]

  A completed trial compared videoscopic versus open inguinal lymphadenectomy for cancer. It includes melanoma and Merkel cell carcinoma among…

• CLINICAL_TRIALS trial_result · 2014-10-03
  Clinical Trial Update: VEGF Trap in Treating Patients With Recurrent, Locally Advanced, or Metastatic Cancer of the Urothelium [Phase 2]

  A Phase 2 trial evaluating VEGF Trap (aflibercept) in patients with recurrent, locally advanced, or metastatic urothelial cancers has comple…

• CLINICAL_TRIALS trial_result · 2013-08-12
  Clinical Trial Update: Pazopanib Hydrochloride in Treating Patients With Metastatic Urethral Cancer or Bladder Cancer That Has Relapsed or Not Responded to Treatment [Phase 2]

  A Phase 2 clinical trial evaluating pazopanib hydrochloride in patients with metastatic bladder cancer, urethral cancer, or transitional cel…

• CLINICAL_TRIALS trial_result · 2013-07-03
  Clinical Trial Update: Combination Chemotherapy in Patients With Advanced Urinary Tract Cancer [Phase 2]

  Phase 2 trial update on combination chemotherapy for advanced urinary tract cancers (bladder cancer and urethral cancer) has completed.

• CLINICAL_TRIALS trial_result · 2013-06-12
  Clinical Trial Update: Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer [Phase 3]

  Phase 3 trial evaluating cisplatin plus gemcitabine with or without paclitaxel in stage IV urinary tract cancers has completed. The study in…

• CLINICAL_TRIALS trial_result · 2013-06-12
  Clinical Trial Update: Combination Chemotherapy in Treating Patients With Transitional Cell Cancer of the Urothelium [Phase 2, Phase 3]

  A Phase 2/Phase 3 clinical trial evaluating combination chemotherapy for transitional cell cancers of the urothelium has completed, includin…

• CLINICAL_TRIALS trial_result · 2013-05-27
  Clinical Trial Update: S0219, Combination Chemotherapy Followed By Observation or Surgery in Patients With Stage II or Stage III Cancer of the Urothelium [Phase 2]

  A Phase 2 SWOG trial evaluating combination chemotherapy followed by observation or surgery in patients with stage II–III urothelial cancer …

• CLINICAL_TRIALS trial_result · 2013-05-03
  Clinical Trial Update: Trastuzumab in Treating Patients With Previously Treated, Locally Advanced, or Metastatic Cancer of the Urothelium [Phase 2]

  Phase 2 trial evaluating trastuzumab for previously treated, locally advanced or metastatic urothelial cancer was terminated.

• CLINICAL_TRIALS trial_result · 2013-03-21
  Clinical Trial Update: Pazopanib in Treating Patients With Metastatic Urothelial Cancer [Phase 2]

  A Phase 2 trial of pazopanib in metastatic urothelial cancer has completed and results have been posted.