Uremic Pruritus
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Study to Investigate the Safety of LT5001 Drug Product for Uremic Pruritus in Hemodialysis Patients [Phase 1, Phase 2]
A Phase 1/2 study evaluating LT5001 for uremic pruritus in hemodialysis patients was terminated; safety results were posted in February 2026…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: A Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus. [Phase 2]
Phase 2 clinical trial of MR13A9 in hemodialysis patients with uremic pruritus has completed, and results were posted on December 5, 2025.
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Phase 3 Study of Difelikefalin in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus [Phase 3]
Phase 3 study of Difelikefalin in Chinese adults on haemodialysis with moderate-to-severe uremic pruritus has completed and results have bee…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: A Phase III Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus. [Phase 3]
A Phase III trial of MR13A9 in hemodialysis patients with uremic pruritus has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Phase 1 Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus [Phase 1]
Phase 1 study evaluating the safety, tolerability, and pharmacokinetics of nalbuphine hydrochloride extended-release tablets in adults under…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysis [Phase 4]
Phase 4 clinical trial comparing fexofenadine to gabapentin for uremic pruritus in patients on regular hemodialysis has completed.
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CLINICAL_TRIALS research · 2024-08-30Clinical Trial Update: The Effect of Probiotics vs Activated Charcoal in the Management of CKD Patients Suffering From Uremic Pruritus. [Phase 2]
A Phase 2 trial compares probiotics versus activated charcoal for managing uremic pruritus in chronic kidney disease. The study is not yet r…
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Phase 3 Study of QLG2198 in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus [Phase 3]
Phase 3 trial of QLG2198 in Chinese adults on haemodialysis with moderate-to-severe pruritus is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-03-27Clinical Trial Update: The Efficacy of Hemp-containing Cream Versus Placebo in the Treatment of Uremic Pruritus [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluated hemp-containing cream versus placebo for uremic pruritus; study completed.
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CLINICAL_TRIALS trial_result · 2023-09-07Clinical Trial Update: AST-120 in Hemodialysis Patients With Uremic Pruritus [Phase 4]
Phase 4 clinical trial update for AST-120 in hemodialysis patients with uremic pruritus has been completed.
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CLINICAL_TRIALS trial_result · 2022-12-14Clinical Trial Update: Sertraline Effect in Uremic Pruritis [Phase 2]
Phase 2 trial assessing sertraline for uremic pruritus has completed.
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CLINICAL_TRIALS trial_result · 2022-09-01Clinical Trial Update: A Study of Thalidomide in the Treatment of Refractory Uremic Pruritus [Phase 4]
A Phase 4 clinical trial evaluating thalidomide for refractory uremic pruritus in haemodialysis patients is ongoing with unknown status.
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CLINICAL_TRIALS trial_result · 2022-08-09Clinical Trial Update: A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of HSK21542 Injection in Subjects Undergoing Hemodialysis [Phase 2]
Phase 2 trial update on HSK21542 injection for uremic pruritus in hemodialysis patients (completed).
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CLINICAL_TRIALS trial_result · 2022-04-26Clinical Trial Update: CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus [Phase 3]
Phase 3 trial update for CR845 in hemodialysis patients with uremic pruritus has completed with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-04-26Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1) [Phase 3]
Phase 3 trial evaluating CR845 in hemodialysis patients with moderate-to-severe pruritus has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-02-09Clinical Trial Update: Efficacy and Safety of MT-9938 for Treatment of Uremic Pruritus in Subjects With End-stage Renal Disease Receiving Hemodialysis [Phase 2]
Phase 2 trial investigating MT-9938 for uremic pruritus in end-stage renal disease patients on hemodialysis was terminated with results post…
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CLINICAL_TRIALS trial_result · 2021-10-15Clinical Trial Update: CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus [Phase 3]
A Phase 3 trial evaluating CR845 for safety and effectiveness in hemodialysis patients with moderate-to-severe pruritus has completed; resul…
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CLINICAL_TRIALS trial_result · 2021-10-14Clinical Trial Update: Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus [Phase 3]
Phase 3 extension study evaluating IV CR845 for moderate-to-severe pruritus in hemodialysis patients has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-07-26Clinical Trial Update: PHOTOTHERAPY VERSUS PREGABALIN IN TREATMENT OF REFRACTORY UREAMIC PRURITIS [Phase 2]
Phase 2 clinical trial comparing phototherapy to pregabalin for refractory uremic pruritus.
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CLINICAL_TRIALS trial_result · 2021-01-28Clinical Trial Update: A Multi-site Bridging Study of Nalfurafine Hydrochloride Orally Disintegrating Tablet [Phase 3]
Phase 3 bridging study investigating nalfurafine hydrochloride orally disintegrating tablet for uremic pruritus.
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CLINICAL_TRIALS trial_result · 2020-09-07Clinical Trial Update: Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus [Phase 2, Phase 3]
Clinical trial update reporting results from Phase 2/3 studies of nalbuphine HCl extended-release tablets for uremic pruritus in hemodialysi…
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CLINICAL_TRIALS trial_result · 2020-09-07Clinical Trial Update: Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritus [Phase 2, Phase 3]
Open-label extension study of nalbuphine ER in hemodialysis patients with uremic pruritus has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-07-29Clinical Trial Update: Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus [Phase 2, Phase 3]
Phase 2/3 trial evaluating IV CR845 (pts) for moderate-to-severe uremic pruritus in hemodialysis patients has completed and results were pos…
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CLINICAL_TRIALS trial_result · 2018-11-29Clinical Trial Update: Comparison of Gabapentin With Doxepin in the Management of Uremic Pruritus [Phase 4]
Phase 4 trial comparing gabapentin with doxepin for management of uremic pruritus has completed.
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Treatment of Uremic Pruritus With PA101B [Phase 2]
A Phase 2 clinical trial evaluating PA101B for treating uremic pruritus has completed.