Upper Tract Urothelial Carcinoma
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Multimodal Kidney-Sparing Strategy for High-Risk Upper Tract Urothelial Carcinoma
This entry updates a trial evaluating a multimodal kidney-sparing strategy for high-risk upper tract urothelial carcinoma; the study is not …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Phase 2A/B Efficacy and Safety of Dabogratinib in Participants With Low Grade Upper Tract Urothelial Carcinoma [Phase 2]
Phase 2A/B study evaluating the efficacy and safety of dabogratinib in participants with Low Grade Upper Tract Urothelial Carcinoma is curre…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Photodynamic Diagnosis of Upper Tract Urothelial Carcinoma Using Fluorescence Endoscopy and Oral 5-ALA [Phase 2]
A Phase 2 clinical trial is investigating photodynamic diagnosis of upper tract urothelial carcinoma using fluorescence endoscopy with oral …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Disitamab Vedotin Plus Radiotherapy for Adjuvant Treatment of HER2-Expressing Cisplatin-Ineligible Upper Tract Urothelial Carcinoma [Phase 2]
Phase 2 clinical trial evaluating disitamab vedotin plus radiotherapy as adjuvant treatment for HER2-expressing cisplatin-ineligible upper t…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Neoadjuvant Chemotherapy Before Surgery vs Surgery Alone for UTUC: A Randomized Trial [Phase 2]
This is a Phase 2 randomized trial comparing neoadjuvant chemotherapy before surgery to surgery alone for upper tract urothelial carcinoma. …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Korean Prospective Upper Tract Urothelial Carcinoma Cohort
A Korean prospective cohort trial focusing on upper tract urothelial carcinoma is currently recruiting, sponsored by Samsung Medical Center.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trial [NA]
This clinical trial status indicates that the Get Moving Trial is recruiting to evaluate a home-based prehabilitation exercise program for p…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: NECTAR Study: Neoadjuvant Toripalimab + 9MW2821 for Local UTUC [Phase 2]
Clinical trial update describing a Phase 2 neoadjuvant study of toripalimab plus 9MW2821 for local upper tract urothelial carcinoma, current…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract [Phase 2]
A Phase 2 study of Enfortumab Vedotin for urothelial carcinoma of the upper urinary tract is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Pembrolizumab and Enfortumab Vedotin With Pembrolizumab Prior to and After Radical Nephroureterectomy for High-Risk Upper Tract Urothelial Cancer [Phase 2]
Phase 2 trial evaluating pembrolizumab with enfortumab vedotin, with pembrolizumab given before and after radical nephroureterectomy for hig…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: ENdoluminal LIGHT ActivatED Treatment of Upper Tract Urothelial Cancer (ENLIGHTED) Study [Phase 3]
Phase 3 clinical trial ENLIGHTED is evaluating endoluminal light-activated treatment for upper tract urothelial carcinoma and is currently r…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Renal Retention in High Grade Upper Tract Urothelial Cancer [Phase 2]
A Phase 2 clinical trial at Johns Hopkins is recruiting to evaluate treatment for high-grade upper tract urothelial carcinoma and bladder ca…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Radical Nephroureterectomy With vs Without Template Lymph Node Dissection in High-Risk Upper Tract Urothelial Carcinoma (T-LND UTUC): A Randomized Clinical Trial [NA]
This randomized clinical trial compares radical nephroureterectomy with template lymph node dissection against radical nephroureterectomy wi…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Efficacy and Safety of Tislelizumab in Combination With Disitamab-vedotin as Neoadjuvant Therapy for HER2-positive High-risk Upper Tract Urothelial Carcinoma (UTUC) [Phase 2]
Phase 2 clinical trial assessing the combination of tislelizumab and disitamab-vedotin as neoadjuvant therapy for HER2-positive high-risk up…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Adjuvant Radioimmunotherapy Compared With Adjuvant Chemotherapy for UTUC
Recruitment is ongoing for a study comparing adjuvant radioimmunotherapy versus adjuvant chemotherapy in patients with upper tract urothelia…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Circulating and Urine Tumor DNA Dynamics Predict Minimal Residual Disease and Recurrence Risk in Locally Advanced Upper Tract Urothelial Carcinoma
A recruiting study evaluating whether circulating and urine tumor DNA dynamics can predict minimal residual disease and recurrence risk in l…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Interest of Magnetic Resonance Imaging in the Diagnosis of Upper Urinary Tract Invasive Tumours [NA]
A clinical trial update from University Hospital, Toulouse evaluating the use of magnetic resonance imaging to diagnose upper tract urotheli…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: SeqUential GeMcitabine and MITomycin Treatment for Favorable High-Risk Upper Urinary Tract Urothelial Carcinoma [Phase 2]
This is a Phase 2 clinical trial from Rutgers evaluating sequential gemcitabine and mitomycin for favorable high‑risk upper tract urothelial…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Urine Methylation Markers in UTUC [NA]
This ClinicalTrials.gov entry notes a recruiting study from Duke University investigating urine methylation markers for upper tract urotheli…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Cisplatin-Based Chemotherapy Followed by Maintenance Avelumab in UTUC [Phase 2]
This clinical trial update describes a Phase 2 study evaluating cisplatin-based chemotherapy followed by maintenance avelumab in upper tract…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Ambulatory Flexible URS for UTUC Surveillance [Phase 1]
Phase 1 clinical trial in Hong Kong assessing ambulatory flexible ureteroscopy for surveillance of upper tract urothelial carcinoma; recruit…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma [Phase 2, Phase 3]
A multicenter clinical trial evaluating the ST-02 therapy for ablation of upper tract urothelial carcinoma (renal pelvis and ureter) is curr…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Nephroureterectomy With and Without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma [NA]
This clinical trial is evaluating nephroureterectomy with and without lymph node dissection for upper tract urothelial carcinoma and is curr…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Neoadjuvant Tislelizumab in Combination With Nab-Paclitaxel for UTUC [Phase 2]
Phase 2 neoadjuvant trial evaluating the PD-1 inhibitor tislelizumab in combination with nab-paclitaxel for upper tract urothelial carcinoma…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Cisplatin-eligible Upper Tract Urothelial Cancer [Phase 2]
A Phase 2 neoadjuvant trial is evaluating the combination of enfortumab vedotin and pembrolizumab for cisplatin-eligible upper tract urothel…