Typhoid Fever
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CLINICAL_TRIALS trial_result · 2018-03-06Clinical Trial Update: Safety and Immunogenicity of Vi-DT Typhoid Conjugate Vaccine (Bio Farma) in Adults and Children (Phase I) [Phase 1]
This Phase I trial evaluated the safety and immunogenicity of the Vi-DT typhoid conjugate vaccine in adults and children, and the study has …
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Salmonella Typhi Vi O-Acetyl Pectin-rEPA Conjugate Vaccine [Phase 1]
Phase 1 clinical trial update showing completion of a Phase 1 study for a Salmonella Typhi Vi O-Acetyl Pectin-rEPA conjugate vaccine for typ…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Long Term Protection by and Persistence of Vi Antibodies Induced by Vi-rEPA Conjugate Vaccines in Vietnamese Children Injected at 2-5 Years or at 5-8 Years of Age
A completed trial in Vietnamese children assessed long-term antibody persistence and protection afforded by the Vi-rEPA conjugate typhoid va…
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Immunogenicity, Safety and Tolerability of the Typhoid Fever Vaccine Candidate M01ZH09 in Healthy Adults [Phase 2]
Phase 2 trial reports on immunogenicity, safety, and tolerability of the typhoid fever vaccine candidate M01ZH09 in healthy adults.
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Gatifloxacin Versus Ceftriaxone in the Treatment of Enteric Fever [Phase 4]
Phase 4 clinical trial comparing gatifloxacin to ceftriaxone for enteric fever (typhoid fever) has completed.
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CLINICAL_TRIALS trial_result · 2014-08-27Clinical Trial Update: Typhoid Fever: Combined vs. Single Antibiotic Therapy [Phase 4]
This document describes a Phase 4 clinical trial evaluating combined antibiotic therapy versus single-agent antibiotic therapy for typhoid f…
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CLINICAL_TRIALS trial_result · 2014-05-12Clinical Trial Update: Study of a Single Dose of SP093 Typhoid Vi Polysaccharide Vaccine in Japanese Subjects [Phase 3]
Phase 3 trial evaluating a single-dose SP093 Typhoid Vi polysaccharide vaccine in Japanese subjects; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: CVD 909 Vi Prime Boost Study [Phase 1]
The update notes the completion of Phase 1 testing for the CVD 909 Vi Prime Boost typhoid vaccine candidate.
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CLINICAL_TRIALS trial_result · 2014-04-10Clinical Trial Update: Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Adults, Children, Older Infants and Infants [Phase 2]
Phase 2 trial evaluating safety and immunogenicity of the Vi-CRM197 typhoid vaccine in adults, children, older infants and infants. Results …
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CLINICAL_TRIALS trial_result · 2014-04-10Clinical Trial Update: Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Children, Older Infants and Infants [Phase 2]
This Phase 2 trial evaluated the safety and immunogenicity of the Vi-CRM197 typhoid vaccine in infants and young children. The results were …
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CLINICAL_TRIALS trial_result · 2014-03-24Clinical Trial Update: Extension Study of H01_04TP to Evaluate the Booster Response Induced by Vi-CRM197 in Adults [Phase 2]
An extension of a Phase 2 trial evaluating the booster immune response to the Vi-CRM197 typhoid vaccine in adults; results were posted in 20…
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CLINICAL_TRIALS trial_result · 2014-03-11Clinical Trial Update: A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults [Phase 3]
Phase 3b, randomized, open-label trial completed to evaluate safety and immunogenicity of select travel vaccines administered concurrently w…
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CLINICAL_TRIALS trial_result · 2012-06-27Clinical Trial Update: Safety, Immunogenicity and Compatibility With DTP of a Typhoid Fever Vaccine in Infants [Phase 2]
Phase 2 study assessing safety, immunogenicity, and compatibility of a typhoid fever vaccine in infants when co-administered with DTP; resul…
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CLINICAL_TRIALS trial_result · 2012-06-13Clinical Trial Update: Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Adult (18-40 Years Old) [Phase 1]
A Phase 1 clinical trial evaluating the safety and immunogenicity of the Vi-CRM197 vaccine against Salmonella Typhi in healthy adults aged 1…
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CLINICAL_TRIALS trial_result · 2012-04-03Clinical Trial Update: Safety and Immunogenicity of Three Formulations of Vi-CRM197 Vaccine Against S. Typhi in Adults (18-40 Years Old) [Phase 2]
Phase 2 study assessing safety and immunogenicity of three formulations of the Vi-CRM197 typhoid conjugate vaccine in adults aged 18-40; res…
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CLINICAL_TRIALS trial_result · 2011-06-10Clinical Trial Update: TY800 Dose Escalation (Typhoid) [Phase 1, Phase 2]
A clinical trial update reports TY800 dose escalation for typhoid; the Phase 1/Phase 2 study has completed.
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CLINICAL_TRIALS trial_result · 2008-08-26Clinical Trial Update: Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in Childhood [Phase 4]
Phase 4 trial evaluating a combined Vi vaccination and health education program to reduce the burden of typhoid and paratyphoid fever in chi…
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CLINICAL_TRIALS trial_result · 2008-08-26Clinical Trial Update: Evaluation of the Vi Polysaccharide Vaccine Against Typhoid Fever [Phase 4]
A Phase 4 trial evaluating the Vi polysaccharide vaccine against Typhoid fever (and Paratyphoid fever) has completed.
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CLINICAL_TRIALS trial_result · 2008-07-02Clinical Trial Update: Dose Ranging Study to Determine the Safety, Reactogenicity and Immunogenicity of Typhoid Fever Vaccine (Ty800) in Healthy Adult Subjects [Phase 2]
Phase 2 dose-ranging study assessing safety, reactogenicity, and immunogenicity of the Ty800 typhoid vaccine in healthy adults; the trial ha…
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CLINICAL_TRIALS trial_result · 2008-03-13Clinical Trial Update: Typhoid Vi Vaccine Effectiveness in Hechi, Guangxi, China [Phase 4]
Phase 4 study assessing the effectiveness of the Typhoid Vi Vaccine against typhoid and paratyphoid fever in Hechi, Guangxi, China; study co…
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CLINICAL_TRIALS trial_result · 2008-03-13Clinical Trial Update: Introduction of the Vi Polysaccharide Typhoid Vaccine in Hue City, Central Vietnam [Phase 4]
Phase 4 trial update on introducing the Vi Polysaccharide Typhoid Vaccine in Hue City, Vietnam.