Type 2 Diabetes Mellitus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: The Role of Metformin and Colesevelam in Human GLP-1 Secretion [Phase 4]
Phase 4 clinical trial update examining how metformin and colesevelam affect GLP-1 secretion in people with type 2 diabetes; the study has c…
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: A Single Dose Study of LY2189265 in Subjects With Varying Degrees of Hepatic (Liver) Impairment [Phase 1]
Phase 1 single-dose study to assess pharmacokinetics of LY2189265 in subjects with varying degrees of hepatic impairment, including those wi…
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose [Phase 1]
A Phase 1 trial by Eli Lilly assessing how LY2189265 affects insulin secretion in response to intravenous glucose in individuals with Type 2…
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: A Study to Compare the Concentrations of LY2189265 After Different Methods of Administration to Healthy Volunteers. [Phase 1]
Phase 1 study comparing concentrations of LY2189265 after different administration methods in healthy volunteers, sponsored by Eli Lilly, in…
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: A Study of the Effect of Dulaglutide on How Body Handles Digoxin in Healthy Participants [Phase 1]
A phase 1 study evaluating whether dulaglutide affects the pharmacokinetics of digoxin in healthy participants, providing data on potential …
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: Salusin-alpha - a New Factor in the Pathogenesis of Lipid Abnormalities in Hemodialysis Patients [Phase 4]
Phase 4 clinical trial update on salusin-α for lipid abnormalities in hemodialysis patients, with the study conducted by Poznan University o…
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CLINICAL_TRIALS trial_result · 2014-10-06Clinical Trial Update: A First-in-Human Study of LY3009385 in Healthy Participants [Phase 1]
First-in-human Phase 1 trial of LY3009385 in healthy participants to evaluate safety, tolerability, and pharmacokinetics; the study complete…
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CLINICAL_TRIALS trial_result · 2014-10-03Clinical Trial Update: Observatory on Elderly Patients "Les S.AGES"
This update reports that the Sanofi-sponsored Observatory on Elderly Patients (Les S.AGES) trial has completed. It covers Type 2 diabetes me…
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CLINICAL_TRIALS trial_result · 2014-10-02Clinical Trial Update: Effects of Different Surgical Methods to Treat Obesity [NA]
This completed clinical trial at Karolinska Institutet comparing different surgical methods for obesity reported results in 2014.
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CLINICAL_TRIALS withdrawal · 2014-10-02Clinical Trial Update: A Cross-Sectional Survey to Evaluate Diabetes Management, Control, Complications, Psychosocial Aspects of Patients With Type 2 Diabetes in Sri Lanka
A cross-sectional survey of Type 2 diabetes mellitus patients in Sri Lanka sponsored by Novo Nordisk A/S has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: RCT Examining Effects of Probiotics in T2DM Individuals [NA]
This entry notes a randomized clinical trial evaluating the effects of probiotics in individuals with Type 2 Diabetes Mellitus and related c…
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FDA approval · 2014-09-30FDA Approved: HUMULIN N — Supplemental Application (Eli Lilly and Company)
FDA approved a supplemental application for Humulin N (insulin human) from Eli Lilly and Company.
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CLINICAL_TRIALS trial_result · 2014-09-30Clinical Trial Update: Efficacy and Safety of BI 10773 in Combination With Insulin in Patients With Type 2 Diabetes [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of BI 10773 in combination with insulin in patients with Type 2 diabetes; results …
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CLINICAL_TRIALS trial_result · 2014-09-30Clinical Trial Update: Vildagliptin and the Glucagon Response to Hypoglycemia in Insulin-Treated Patients With Type 2 Diabetes [Phase 4]
This update reports on a Phase 4 study examining how vildagliptin influences the glucagon response to hypoglycemia in insulin-treated patien…
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CLINICAL_TRIALS trial_result · 2014-09-30Clinical Trial Update: An Open Study to Evaluate Whether Pack Size Affects Compliance of Metformin Treatment in Subjects With Type II Diabetes [Phase 4]
An open-label Phase 4 trial assessed whether pack size influences adherence to metformin in adults with type 2 diabetes; the study was termi…
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CLINICAL_TRIALS trial_result · 2014-09-29Clinical Trial Update: Safety and Efficacy of BGP-15 in Patients With Type 2 Diabetes Mellitus [Phase 2]
A Phase 2 study evaluated the safety and efficacy of BGP-15 in adults with type 2 diabetes mellitus, but the trial was terminated.
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EMA withdrawal · 2014-09-26EMA Withdrawn: Pioglitazone Krka (pioglitazone hydrochloride) — Krka, d.d., Novo mesto
Pioglitazone Krka (pioglitazone hydrochloride) has been withdrawn from the EU market.
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CLINICAL_TRIALS trial_result · 2014-09-25Clinical Trial Update: Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus [Phase 1]
Phase 1 clinical trial evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of LGD-6972 in healthy subjects and individual…
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CLINICAL_TRIALS trial_result · 2014-09-25Clinical Trial Update: The Effect of Ethanol on Overnight Glucose Regulation in Type 2 [NA]
Completed clinical trial evaluating the effect of ethanol on overnight glucose regulation in individuals with insulin-requiring Type 2 diabe…
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CLINICAL_TRIALS trial_result · 2014-09-23Clinical Trial Update: A Phase 3 Study of Ranolazine in Subjects With Type 2 Diabetes Who Are Inadequately Controlled on Metformin Alone [Phase 3]
Phase 3 study of ranolazine in adults with type 2 diabetes inadequately controlled on metformin completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2014-09-23Clinical Trial Update: Influence of Diabetes on Tramadol Pharmacokinetics [Phase 4]
Phase 4 trial evaluating how diabetes status influences tramadol pharmacokinetics in patients with neuropathic pain.
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CLINICAL_TRIALS trial_result · 2014-09-22Clinical Trial Update: VERifynow in DIabetes Non-responsiveness: a Study on Switching From Clopidogrel to Prasugrel [Phase 4]
Completed Phase 4 study evaluating switching from clopidogrel to prasugrel in patients with type 2 diabetes mellitus and acute coronary synd…
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CLINICAL_TRIALS trial_result · 2014-09-22Clinical Trial Update: Bed Rest, Alternate Daily Fasting and Incretin Effect [NA]
A completed clinical study evaluating bed rest and alternate-day fasting effects on incretin response in people with metabolic syndrome and …
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CLINICAL_TRIALS trial_result · 2014-09-19Clinical Trial Update: Empowering Primary Care Providers and Patients to Improve Chronic Disease Outcomes: The EMPOWER Participatory Action Research (EMPOWER - PAR) [EARLY_Phase 1]
This clinical trial update reports the EARLY Phase 1 EMPOWER Participatory Action Research study, aimed at empowering primary care providers…
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FDA approval · 2014-09-18FDA Approved: TRULICITY — Original Application (Eli Lilly and Company)
The FDA approved the original application for TRULICITY (dulaglutide) from Eli Lilly and Company, authorizing its marketing for adults with …