Type 2 Diabetes Mellitus
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CLINICAL_TRIALS trial_result · 2014-10-20Clinical Trial Update: Efficacy of Lubiprostone in Combination With Standard PEG Preparation [NA]
A terminated clinical trial evaluated the efficacy of lubiprostone in combination with standard polyethylene glycol (PEG) preparation in pat…
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CLINICAL_TRIALS trial_result · 2014-10-17Clinical Trial Update: Comparison of Technosphere® Insulin Versus Technosphere Powder (Placebo) in Insulin-Naive Subjects With Type 2 Diabetes Mellitus [Phase 3]
A Phase 3 randomized trial compares Technosphere Insulin with placebo (Technosphere Powder) in insulin-naive adults with Type 2 diabetes. Re…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Efficacy and Safety of Prandial Inhalation of Technosphere/Insulin in Combination With Metformin or Technosphere/Insulin Alone Versus 2 Oral Anti-Diabetic Agents in Subjects With Type 2 Diabetes [Phase 3]
Phase 3 trial evaluating prandial inhaled insulin (Technosphere/insulin) with or without metformin, compared to two oral antidiabetic agents…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: An Open-label, Multi-center, International, Three-year, Safety and Tolerability 'Follow on' Trial [Phase 2]
A completed Phase 2 open-label follow-on study conducted across multiple centers. It evaluated safety and tolerability of inhaled insulin in…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Efficacy and Safety in Subjects With Type 2 Diabetes Receiving Subcutaneous Basal Insulin and Prandial Inhalation of Technosphere/Insulin Versus Subcutaneous Premixed Insulin Therapy Over a 52-Week Treatment Period and a 4-Week Follow-up [Phase 3]
Phase 3 study evaluating the efficacy and safety of Technosphere insulin (inhaled) versus subcutaneous premixed insulin over 52 weeks in adu…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Safety of Inhaled Insulin With Type 1 and Type 2 Diabetes [Phase 3]
Phase 3 trial safety results for inhaled insulin in adults with Type 1 and Type 2 diabetes are reported. The study is completed, with result…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: A Study Comparing Subcutaneous Rapid Acting Insulin and One Formulation of Inhaled Insulin in Subjects With Type 2 Diabetes [Phase 2]
A Phase 2 trial comparing subcutaneous rapid-acting insulin with a formulation of inhaled insulin in adults with Type 2 diabetes completed, …
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Weight Loss Study for People With Type 2 Diabetes [Phase 3]
A Phase 3 weight loss trial in adults with type 2 diabetes has completed, evaluating weight loss outcomes in overweight and obese participan…
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Ranolazine Monotherapy in Subjects With Type 2 Diabetes Mellitus [Phase 3]
Phase 3 trial evaluating ranolazine as a monotherapy in adults with type 2 diabetes mellitus; the study has completed and results have been …
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Phase 1 Multicenter, Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Response of PE0139 Injection in Adult Subjects With Type 2 Diabetes Mellitus [Phase 1]
Phase 1 multicenter single ascending-dose trial of PE0139 in adults with Type 2 Diabetes Mellitus completed, assessing safety, tolerability,…
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Fat-induced Release of GLP-1 in Humans [NA]
This clinical trial update describes a study on fat-induced GLP-1 release in humans with Type 2 diabetes mellitus and notes that the trial h…
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CLINICAL_TRIALS research · 2014-10-15Clinical Trial Update: Exercise as a Tool for Studying the Mechanisms and Applicability of Glycemic Variability [NA]
A clinical trial exploring exercise as a tool to study the mechanisms and applicability of glycemic variability in Type 2 diabetes mellitus.
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CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: A Clinical Trial to Study the Effect of Lycopene in Patients With Gum Disease and type2 Diabetes Mellitus [Phase 4]
Phase 4 clinical trial evaluating the effect of lycopene in patients with periodontal disease and type 2 diabetes mellitus has completed.
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CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: Assessing the Risk of Developing Type II Diabetes Using Serum Biomarkers in Patients Diagnosed With Obstructive Sleep Apnea [NA]
This completed clinical trial evaluates whether serum biomarkers can predict the development of type 2 diabetes in patients with obstructive…
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CLINICAL_TRIALS trial_result · 2014-10-09Clinical Trial Update: A Study in Adults With Type 2 Diabetes [Phase 3]
A Phase 3 trial in adults with Type 2 diabetes has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2014-10-09Clinical Trial Update: A Study Comparing the Effect of Dulaglutide With Liraglutide in Type 2 Diabetes [Phase 3]
Phase 3 head-to-head study comparing dulaglutide with liraglutide in type 2 diabetes has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2014-10-09Clinical Trial Update: -Oleoyl Glycerol is a GPR119 Agonist and Signals GLP-1 Release in Humans. [NA]
A completed clinical trial indicates that oleoyl glycerol acts as a GPR119 agonist and stimulates GLP-1 release in humans, studied in Type 2…
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CLINICAL_TRIALS trial_result · 2014-10-08Clinical Trial Update: Efficacy and Safety of DLBS3233 in Subjects With New Onset of Type 2 Diabetes Mellitus [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of DLBS3233 in adults with new-onset type 2 diabetes mellitus has completed.
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CLINICAL_TRIALS trial_result · 2014-10-08Clinical Trial Update: A Study in Participants With Type 2 Diabetes Mellitus (AWARD-4) [Phase 3]
AWARD-4, a Phase 3 trial in adults with type 2 diabetes mellitus, has completed and posted results.
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CLINICAL_TRIALS trial_result · 2014-10-08Clinical Trial Update: A Study of the Effect of Dulaglutide on How the Body Handles Oral Contraceptive in Healthy Female Participants [Phase 1]
Phase 1 study to assess whether dulaglutide alters the metabolism of oral contraceptives in healthy female participants; completed with resu…
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CLINICAL_TRIALS trial_result · 2014-10-08Clinical Trial Update: A Study of the Effect of LY2189265 on Two Blood Pressure Drugs [Phase 1]
Phase 1 study evaluating the investigational drug LY2189265 for its interaction with two antihypertensive medications in adults with Type 2 …
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: A Study to Evaluate the Effect of LY2189265 on the Speed at Which Food and Drink Leaves the Stomach in Patients With Type 2 Diabetes Mellitus [Phase 1]
A Phase 1 trial evaluated the effect of LY2189265 on gastric emptying in adults with Diabetes Mellitus, Type 2; the study has completed and …
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: Study of Safety, Tolerability and Pharmacokinetics of Single Oral JTT-251 Doses in Healthy and Type 2 Diabetic Subjects [Phase 1]
A Phase 1 study evaluating the safety, tolerability and pharmacokinetics of single oral doses of JTT-251 in healthy subjects and in individu…
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: A Study of LY2189265 and Sitagliptin in Participants With Type 2 Diabetes [Phase 1]
Phase 1 study evaluating LY2189265 in combination with sitagliptin in participants with Type 2 diabetes; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: A Study of the Effect of Dulaglutide on the Action of Warfarin in Healthy Participants [Phase 1]
Phase 1 pharmacokinetic study to evaluate whether dulaglutide affects warfarin activity in healthy participants; results were posted in 2014…