Type 2 Diabetes Mellitus
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CLINICAL_TRIALS trial_result · 2017-08-03Clinical Trial Update: The Effectivity and Safety Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus [Phase 3]
A Phase 3 clinical trial evaluating the effectiveness and safety of rExenatide-4 for Type 2 diabetes mellitus in Chinese patients; current s…
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CLINICAL_TRIALS trial_result · 2017-08-03Clinical Trial Update: In Vivo Leptin Signaling in Humans After Acute Leptin Administration [Phase 1]
Phase 1 clinical trial update examining in vivo leptin signaling in humans after acute leptin administration in lean and obese individuals, …
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CLINICAL_TRIALS trial_result · 2017-08-03Clinical Trial Update: Diabetes Resistance Training Adaptations in Elderly [NA]
A clinical trial assessing resistance training adaptations in elderly individuals with Type 2 diabetes has completed.
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CLINICAL_TRIALS research · 2017-08-03Clinical Trial Update: The Japan Diabetes Optimal Integrated Treatment Study for 3 Major Risk Factors of Cardiovascular Diseases [NA]
This is a clinical trial update for the Japan Diabetes Optimal Integrated Treatment Study evaluating three major cardiovascular risk factors…
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CLINICAL_TRIALS trial_result · 2017-08-03Clinical Trial Update: Lifestyle Control of Postprandial Hyperglycemia [NA]
A completed clinical trial evaluating lifestyle measures to control postprandial blood glucose in adults with Type 2 diabetes mellitus.
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CLINICAL_TRIALS research · 2017-08-03Clinical Trial Update: BEYO Project to Promote Sense of Coherence and Self-care of Elderly People With Type 2 Diabetes [NA]
This entry outlines a clinical trial (NCT03237975) led by the Chinese University of Hong Kong to promote sense of coherence and self-care in…
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: Efficacy and Safety of Vildagliptin in Combination With Metformin in Patients With Type 2 Diabetes [Phase 3]
Phase 3 clinical trial assessing the efficacy and safety of vildagliptin combined with metformin in adults with type 2 diabetes; the study h…
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: Effect of Vildagliptin vs. Glibenclamide on Circulating Endothelial Progenitor Cell Number Type 2 Diabetes [Phase 3]
Phase 3 trial comparing vildagliptin to glibenclamide in Type 2 diabetes assessed circulating endothelial progenitor cell counts; results ha…
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: A Non-interventional, Post Marketing Surveillance (PMS) Study of Tresiba® (Insulin Degludec) to Evaluate Long Term Safety and Efficacy in Patients With Diabetes Mellitus in Routine Clinical Practice in India
A non-interventional post-marketing surveillance study evaluating the long-term safety and efficacy of insulin degludec (Tresiba) in routine…
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: A Study to Explore the Effects of Azilsartan Compared to Telmisartan on Insulin Resistance of Patients With Essential Hypertension on Type 2 Diabetes Mellitus by HOMA-R [Phase 4]
Phase 4 clinical trial comparing azilsartan to telmisartan on insulin resistance in patients with essential hypertension and type 2 diabetes…
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: Energy Flux and Fat Oxidation Using Low and High Glycaemic Index Foods [NA]
This completed clinical trial from the Singapore Institute of Food and Biotechnology Innovation examined energy flux and fat oxidation when …
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: The Influence of Glucose Flux on Fat Synthesis in a Whole Body Calorimeter [NA]
A completed clinical trial investigated how glucose flux influences fat synthesis in humans using a whole-body calorimeter, with participant…
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: A 56-Week Extension to a Clinical Study to Assess the Efficacy and Safety of Vildagliptin Compared to Placebo in Drug Naive Patients With Type 2 Diabetes and Mild Hyperglycemia [Phase 3]
A 56-week extension of a Phase 3 study assessing the efficacy and safety of vildagliptin versus placebo in drug-naive patients with type 2 d…
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FDA approval · 2017-08-01FDA Approved: TRULICITY — Supplemental Application (Eli Lilly and Company)
The FDA approved a supplemental application for Trulicity (dulaglutide) submitted by Eli Lilly and Company. The action confirms approval of …
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CLINICAL_TRIALS trial_result · 2017-08-01Clinical Trial Update: Efficacy and Safety of Combination Therapy of Vildagliptin/Metformin in Patients in Type 2 Diabetes Mellitus (T2DM) [Phase 4]
This document provides an update on a Phase 4 trial evaluating the efficacy and safety of the fixed-dose combination vildagliptin/metformin …
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CLINICAL_TRIALS research · 2017-07-31Clinical Trial Update: Skeletal Muscle Lipid and Insulin Resistance: Effects of Physical Activity and Weight Loss [NA]
A completed University of Pittsburgh clinical trial investigating how physical activity and weight loss affect skeletal muscle lipid content…
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FDA approval · 2017-07-28FDA Approved: DAPAGLIFLOZIN AND METFORMIN HYDROCHLORIDE — Supplemental Application (Prasco Laboratories)
The FDA approved a supplemental application for Dapagliflozin and Metformin Hydrochloride (Prasco Laboratories), authorizing a new combinati…
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CLINICAL_TRIALS trial_result · 2017-07-28Clinical Trial Update: Drug to Drug Interaction Study With ASP1941 and Metformin [Phase 1]
A Phase 1 study evaluating potential drug–drug interaction between ASP1941 and metformin in Type 2 Diabetes Mellitus has been completed.
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CLINICAL_TRIALS research · 2017-07-28Clinical Trial Update: Measurement of Alanine Aminotransaminase (ALT) Following Initiation of Antidiabetic Agents in Patients With Type 2 Diabetes in a Real-world Clinical Setting: a Retrospective Cohort Study
This completed retrospective cohort study evaluated ALT changes after initiation of antidiabetic therapy in adults with type 2 diabetes, inc…
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CLINICAL_TRIALS trial_result · 2017-07-27Clinical Trial Update: SMBG Protocols Predicting Glucose Levels in Senior Diabetes Mellitus With CAD [NA]
This completed clinical trial update evaluates SMBG-based protocols for predicting glucose levels in older adults with type 2 diabetes melli…
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CLINICAL_TRIALS trial_result · 2017-07-27Clinical Trial Update: Nutritional Prevention of Diabetes Mellitus Type 2 [NA]
This completed clinical trial evaluates nutritional prevention strategies for Type 2 Diabetes Mellitus and assesses effects on liver fat and…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetic a Single Day of Dosing With GSK1614235. [Phase 1]
A Phase 1 study evaluated the safety, tolerability, and pharmacokinetics of a single day of dosing with GSK1614235 in adults with Type 2 dia…
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CLINICAL_TRIALS research · 2017-07-26Clinical Trial Update: Fat Metabolites and Gut Hormones [NA]
A study from Hvidovre University Hospital is examining how fat metabolites and gut hormones relate to obesity and type 2 diabetes. The curre…
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: Screening, Brief Intervention, and Referral to Treatment in Primary Care [NA]
Completed clinical trial evaluating Screening, Brief Intervention, and Referral to Treatment (SBIRT) in primary care for patients with type …
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: Microvascular Dysfunction and the Development of Whole-body Insulin Resistance [NA]
A completed clinical trial from Amsterdam UMC investigated whether microvascular dysfunction contributes to the development of whole-body in…