Tuberculous Meningitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS other · 2026-04-14Clinical Trial Update: B-PaLMZ for TB Meningitis [Phase 2]
A Phase 2 clinical trial of B-PaLMZ for tuberculous meningitis is not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Phase 2a Trial of Alpibectir Plus Ethionamide for Tuberculosis Meningitis [Phase 2]
A Phase 2a trial of Alpibectir plus Ethionamide for tuberculous meningitis is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Evaluation of New Biomarker-based Approaches for Improving the Diagnosis of Childhood Tuberculous Meningitis
This completed clinical trial evaluated biomarker-based approaches to improve the diagnosis of childhood tuberculous meningitis.
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Tnf Inhibitors to Reduce Mortality in HIV-1 Infected PAtients With Tuberculosis meNIngitis [Phase 2]
A Phase 2 clinical trial evaluating tumor necrosis factor (TNF) inhibitors to reduce mortality in people with HIV infection and tuberculous …
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis [Phase 2]
This Phase 2 trial is evaluating a six-month high-dose rifampicin, high-dose isoniazid, linezolid, and pyrazinamide regimen versus a standar…
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Adjunctive Doxycycline for Central Nervous System Tuberculosis [Phase 2]
Phase 2 clinical trial evaluating adjunctive doxycycline for central nervous system tuberculosis (including tuberculous meningitis) is curre…
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CLINICAL_TRIALS trial_result · 2025-06-17Clinical Trial Update: Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous Meningitis [Phase 3]
Phase 3 trial update evaluating adjunctive corticosteroids for tuberculous meningitis in HIV-uninfected adults, with stratification by leuko…
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CLINICAL_TRIALS trial_result · 2025-02-06Clinical Trial Update: Intrathecal Therapy for Adult Tuberculous Meningitis: Impact on Clinical Outcomes
A completed clinical trial evaluating intrathecal therapy for adult tuberculous meningitis and its impact on clinical outcomes.
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: Phase II Clinical Study of Contezolid for the Treatment of Tuberculous Meningitis [Phase 1, Phase 2]
An ongoing Phase I/II clinical trial of contezolid for tuberculous meningitis is currently enrolling by invitation.
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Adjunctive Linezolid for the Treatment of Tuberculous Meningitis [Phase 2]
Phase 2 trial of adjunctive linezolid for tuberculous meningitis has completed. Results have been posted.
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CLINICAL_TRIALS trial_result · 2024-03-22Clinical Trial Update: Adjunctive Corticosteroids for Tuberculous Meningitis in HIV-infected Adults (The ACT HIV Trial) [Phase 3]
Phase 3 clinical trial assessing adjunctive corticosteroids for tuberculous meningitis in HIV-infected adults has completed.
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CLINICAL_TRIALS trial_result · 2024-01-22Clinical Trial Update: Intensified Tuberculosis Treatment to Reduce the Mortality of Patients With Tuberculous Meningitis [Phase 3]
Phase 3 trial evaluating intensified tuberculosis treatment to reduce mortality in patients with tuberculous meningitis is currently recruit…
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CLINICAL_TRIALS trial_result · 2023-12-21Clinical Trial Update: Intensified Short Course Regimen for TBM in Adults [Phase 3]
Phase 3 clinical trial update on an intensified short-course regimen for tuberculous meningitis in adults; status not yet recruiting.
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CLINICAL_TRIALS trial_result · 2021-10-28Clinical Trial Update: Optimizing Treatment to Improve TBM Outcomes in Children [Phase 1, Phase 2]
Phase 1/2 clinical trial update exploring optimized treatment to improve outcomes in children with tuberculous meningitis.
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CLINICAL_TRIALS trial_result · 2020-12-30Clinical Trial Update: Cyclophosphamide in the Treatment of Refractory Proliferative Arachnoiditis in CNS Tuberculosis [Phase 2, Phase 3]
Phase 2/3 trial evaluating cyclophosphamide for refractory proliferative arachnoiditis in CNS tuberculosis is ongoing with unknown status.
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: High-dose Rifampicin for the Treatment of Tuberculous Meningitis: a Dose-finding Study [Phase 2, Phase 3]
Phase 2/3 trial evaluating high-dose rifampicin for tuberculous meningitis to determine the optimal dosing.
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CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: A Pilot Study of Adjunctive Aspirin for the Treatment of HIV Negative Adults With Tuberculous Meningitis [Phase 2]
A Phase 2 pilot trial evaluating adjunctive aspirin for HIV-negative adults with tuberculous meningitis has completed.
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC [Phase 3]
A Phase 3 clinical trial in the Democratic Republic of Congo evaluating rapid diagnostic tests and clinical/laboratory predictors for cerebr…
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CLINICAL_TRIALS research · 2015-10-29Clinical Trial Update: The Relationships Between Gene Polymorphisms of LTA4H and Dexamethasone Treatment for Tuberculous Meningitis [Phase 4]
A Phase 4 clinical trial update examining the relationship between LTA4H gene polymorphisms and dexamethasone treatment in tuberculous menin…
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CLINICAL_TRIALS trial_result · 2014-08-20Clinical Trial Update: Diagnosis of Tuberculous Meningitis by ESAT-6 in CSF
A completed clinical trial evaluating the use of ESAT-6 in cerebrospinal fluid for the diagnosis of tuberculous meningitis.
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CLINICAL_TRIALS trial_result · 2014-06-17Clinical Trial Update: Rifampicin Explorative PK Study for Tuberculous Meningitis Comparing Oral and Intravenous Preparation [Phase 2]
A phase 2 explorative pharmacokinetic study comparing oral and intravenous rifampicin for tuberculous meningitis has completed.
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CLINICAL_TRIALS trial_result · 2012-06-07Clinical Trial Update: Intensified Treatment Regimens for TB Meningitis: PK, PD and Tolerability Study [Phase 2]
Phase 2 clinical trial evaluating intensified treatment regimens for tuberculous meningitis, with a focus on pharmacokinetics, pharmacodynam…
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CLINICAL_TRIALS trial_result · 2011-09-15Clinical Trial Update: Study Of The Long Term Outcome Of Tuberculous Meningitis In Vietnamese Adults Treated With Adjunctive Dexamethasone
This completed trial assesses long-term outcomes in Vietnamese adults with tuberculous meningitis treated with adjunctive dexamethasone.
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CLINICAL_TRIALS research · 2008-08-07Clinical Trial Update: Immediate Versus Deferred Antiretroviral Therapy for HIV-Associated Tuberculous Meningitis [NA]
This entry discusses a clinical trial comparing immediate versus deferred initiation of antiretroviral therapy in HIV-infected patients with…