Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Biodistribution and Pharmacokinetics of Pretomanid in Tuberculosis Patients Using 18F-Pretomanid PET
A completed Johns Hopkins-sponsored study investigates biodistribution and pharmacokinetics of pretomanid in tuberculosis patients using 18F…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: ID93/GLA-SE Vaccination + BCG Challenge [NA]
This is a clinical trial update for a tuberculosis vaccine approach using ID93/GLA-SE with a BCG challenge. The trial is currently active bu…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS) [Phase 1, Phase 2]
This update describes a Phase 1/2 trial evaluating rifapentine plus isoniazid (3HP) as TB preventive therapy for children on dolutegravir-ba…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: TB SCReening Improves Preventive Therapy Uptake in Pregnant Women With HIV [NA]
A clinical trial to evaluate whether TB screening improves uptake of preventive therapy among pregnant women with HIV; the study is currentl…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: A Study to Evaluate the Safety and Immunogenicity of Ad5-105K in Adults Aged 18 to 49 Years [Phase 1]
This document provides an update on a Phase 1 trial evaluating the safety and immunogenicity of the Ad5-105K candidate in adults aged 18–49.…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Safety and Efficacy of RUTI® With the Standard of Treatment for Tuberculosis [Phase 2]
Phase 2 trial evaluating safety and efficacy of RUTI® in combination with standard tuberculosis therapy has completed.
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Development of a Diagnostic Prediction Score for Tuberculosis in Hospitalized Children With Severe Acute Malnutrition (TB-Speed SAM) [NA]
Clinical trial update describing the development of a diagnostic prediction score for tuberculosis in hospitalized children with severe acut…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Innovating Shorter, All- Oral, Precised Treatment Regimen for Rifampicin Resistant Tuberculosis：BLMZ Chinese Cohort [Phase 3]
Phase 3 trial update evaluating a shorter, all-oral, precision treatment regimen for rifampicin-resistant tuberculosis in a Chinese cohort; …
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Impact of Systematic Early Tuberculosis Detection Using Xpert MTB/RIF Ultra in Children With Severe Pneumonia in High Tuberculosis Burden Countries (TB-Speed Pneumonia) [NA]
Clinical trial update on the completion of the TB-Speed Pneumonia study assessing systematic early tuberculosis detection using Xpert MTB/RI…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin [Phase 1]
A Phase 1 clinical trial update examining how dolutegravir behaves pharmacokinetically in HIV-infected children coinfected with tuberculosis…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Start Taking Action for Tuberculosis in Kids [NA]
This is a clinical trial update for a pediatric tuberculosis study that is not yet recruiting. The sponsor is Liverpool School of Tropical M…
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EMA approval · 2025-11-24EMA Authorised: Sirturo (bedaquiline fumarate) — Janssen-Cilag International N.V.
EMA authorised Sirturo (bedaquiline fumarate) for treatment of tuberculosis, including multidrug-resistant tuberculosis. The decision date i…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Start Taking Action For TB Diagnosis
This entry reports that a Liverpool School of Tropical Medicine-led trial for improving tuberculosis diagnosis has completed.
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: DoseTB-individualised Dosing by Model-informed Precision Dosing for Pulmonary Tuberculosis
A Karolinska Institutet clinical trial is investigating DoseTB, an individualized, model-informed dosing approach for pulmonary tuberculosis…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Feasibility of Tracheobronchial Reconstruction Using Allogenic Aortic Patch in Children [NA]
This clinical trial evaluates the feasibility of tracheobronchial reconstruction in children using an allogenic aortic patch and is currentl…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Acoustic Cough Monitoring for the Management of Patients With Known Respiratory Disease
This clinical trial update reports on the use of acoustic cough monitoring to manage patients with known respiratory diseases; the study sta…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Effectiveness of Chat-based Mobile Application for Consultation (Zalo) in Improving Compliance With Follow-up Tests After Abnormal Chest X-ray Findings Interpret by Artificial Intelligent [NA]
A clinical trial is evaluating a chat-based mobile app (Zalo) to improve compliance with follow-up tests after AI-interpreted abnormal chest…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Plasma MTB cfDNA Before Bronchoscopy
An ongoing clinical trial from the Chinese University of Hong Kong is evaluating plasma Mycobacterium tuberculosis cell-free DNA before bron…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Rapid Research in Diagnostics Development for TB Network [NA]
Clinical trial update on Rapid Research in Diagnostics Development for TB Network, a recruiting study led by UCSF investigating TB diagnosti…
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum
A clinical trial update reporting pharmacokinetic properties of antiretroviral and anti-tuberculosis drugs during pregnancy and postpartum.
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: Tuberculosis - Learning the Effect of Parasites and Reinforcing Diets
A completed clinical trial investigates the impact of parasites and dietary factors on tuberculosis. It also covers related conditions such …
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EMA approval · 2025-10-24EMA Authorised: Siiltibcy (Mycobacterium tuberculosis derived antigens (rdESAT‑6 and rCFP‑10)) — Serum Life Science Europe GmbH
EMA has authorised Siiltibcy, a tuberculosis diagnostic product using M. tuberculosis–derived antigens rdESAT-6 and rCFP-10, developed by Se…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Closing -TB GAPs - for People Living With HIV: TB Guidance for Adaptable Patient-Centered Service [NA]
This clinical trial record describes TB GAPs to provide adaptable, patient-centered TB guidance for people living with HIV; the study is in …
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Single-Dose Study to Evaluate the PKs of Pretomanid in Participants With Renal Impairment Compared to Participants With Normal Renal Function [Phase 1]
Phase 1, single-dose pharmacokinetic study comparing pretomanid in participants with renal impairment to those with normal renal function; r…
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FDA approval · 2025-10-08FDA Approved: RIFADIN IV — Supplemental Application (Sanofi-Aventis U.S. LLC)
The FDA approved a supplemental application for Rifadin IV (rifampin) submitted by Sanofi-Aventis U.S. LLC. This action covers the intraveno…