Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2009-08-04Clinical Trial Update: Nutrition, Diabetes and Pulmonary TB/HIV [Phase 3]
A Phase 3 clinical trial investigating nutrition, diabetes, and pulmonary tuberculosis/HIV has completed.
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CLINICAL_TRIALS trial_result · 2009-07-16Clinical Trial Update: The Effectiveness of Health Facility-based and Community-based Care for Tuberculosis [Phase 4]
Phase 4 trial evaluating the effectiveness of health facility-based versus community-based care for tuberculosis, completed.
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CLINICAL_TRIALS trial_result · 2009-07-09Clinical Trial Update: Rapid Characterization of Paucibacillary TB Along Tex/Mex Border
This completed trial from The University of Texas Health Science Center, Houston, reports rapid characterization of paucibacillary tuberculo…
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CLINICAL_TRIALS trial_result · 2009-06-25Clinical Trial Update: Early Bactericidal Activity of Linezolid, Gatifloxacin, Levofloxacin, Isoniazid (INH) and Moxifloxacin in HIV Negative Adults With Initial Episodes of Sputum Smear-Positive Pulmonary Tuberculosis [Phase 1, Phase 2]
Early bactericidal activity data for multiple drugs (linezolid, gatifloxacin, levofloxacin, isoniazid, moxifloxacin) in HIV-negative adults …
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FDA approval · 2009-06-17FDA Approved: ETHAMBUTOL HYDROCHLORIDE — Original Application (Lupin Pharmaceuticals, Inc.)
FDA approves Lupin Pharmaceuticals' Ethambutol Hydrochloride as an original ANDA, enabling the generic product to enter the market.
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FDA approval · 2009-06-01FDA Approved: PRIFTIN — Supplemental Application (sanofi-aventis U.S. LLC)
The FDA approved a supplemental application for PRIFTIN (rifapentine) submitted by Sanofi-Aventis U.S. LLC.
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CLINICAL_TRIALS trial_result · 2009-04-22Clinical Trial Update: Investigation of the Effect of N Acetylcysteine Against Anti-Tuberculosis Drugs Induced Liver Toxicity [NA]
A completed clinical trial evaluated the effect of N-acetylcysteine in preventing or mitigating liver toxicity caused by anti-tuberculosis d…
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CLINICAL_TRIALS trial_result · 2009-04-14Clinical Trial Update: Effectiveness of the TB Contact Priority Model
NHLBI-sponsored trial completed to evaluate the effectiveness of a tuberculosis contact priority model.
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CLINICAL_TRIALS trial_result · 2009-03-25Clinical Trial Update: Clinical Trial to Study 4 Different Doses of the Vaccine RUTI in Healthy Volunteers [Phase 1]
A Phase 1 trial evaluated four different doses of the RUTI vaccine in healthy volunteers, with results posted. The study focused on latent t…
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CLINICAL_TRIALS trial_result · 2009-03-06Clinical Trial Update: Arginine as an Adjuvant Treatment Against Tuberculosis [NA]
This entry notes the completed status of a clinical trial evaluating arginine as an adjunct treatment for tuberculosis, including participan…
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CLINICAL_TRIALS trial_result · 2008-12-31Clinical Trial Update: Short-Course Isoniazid and Rifampin Compared With Isoniazid for Latent Tuberculosis Infection [Phase 4]
A Phase 4 trial comparing short-course isoniazid plus rifampin versus isoniazid alone for latent tuberculosis infection was terminated.
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CLINICAL_TRIALS trial_result · 2008-11-03Clinical Trial Update: A Phase I Trial of a LTK63 Adjuvated Tuberculosis Nasal Subunit Vaccine (Ag85B-ESAT6) [Phase 1]
Phase I trial evaluating a nasal subunit tuberculosis vaccine with LTK63 adjuvant (Ag85B-ESAT6); the study is terminated.
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FDA approval · 2008-10-30FDA Approved: ETHAMBUTOL HYDROCHLORIDE — Supplemental Application (Marlex Pharmaceuticals, Inc.)
FDA approved a supplemental application for Ethambutol Hydrochloride submitted by Marlex Pharmaceuticals under NDA 016320.
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CLINICAL_TRIALS research · 2008-10-27Clinical Trial Update: Spatial Epidemiology of Tuberculosis (TB) Infection
This item provides an update on a clinical trial evaluating the spatial epidemiology of tuberculosis infection, sponsored by National Taiwan…
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CLINICAL_TRIALS trial_result · 2008-10-24Clinical Trial Update: A Randomized Trial of Three Regimens to Prevent Tuberculosis in HIV-Infected Patients With Anergy [Phase 4]
This Phase 4 randomized trial compares three regimens to prevent tuberculosis in HIV-infected patients with anergy; the study has completed.
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CLINICAL_TRIALS trial_result · 2008-10-21Clinical Trial Update: Revaccination of Young Children With Bacille Calmette Guerin (BCG) Vaccine [Phase 4]
A phase 4 trial evaluating revaccination with the Bacille Calmette-Guérin (BCG) vaccine in young children was terminated.
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CLINICAL_TRIALS trial_result · 2008-09-17Clinical Trial Update: Diagnosing Tuberculosis in HIV Infected Children in Peru
This is a completed clinical trial in Peru focusing on diagnosing tuberculosis in HIV-infected children.
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CLINICAL_TRIALS trial_result · 2008-09-11Clinical Trial Update: Effectiveness of Anti-HIV Therapy (HAART) in HIV-Infected Patients With Tuberculosis [Phase 1]
Phase 1 clinical trial evaluating the effectiveness of Highly Active Antiretroviral Therapy (HAART) in HIV-infected patients with tuberculos…
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CLINICAL_TRIALS trial_result · 2008-08-25Clinical Trial Update: TBTC Study 26 PK: Rifapentine Pharmacokinetics in Children During Treatment of Latent TB Infection [NA]
A completed study evaluating the pharmacokinetics of rifapentine in children during treatment of latent tuberculosis infection.
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CLINICAL_TRIALS trial_result · 2008-08-08Clinical Trial Update: A Pilot Study of Methodology to Rapidly Evaluate Drugs for Bactericidal Activity, Tolerance, and Pharmacokinetics in the Treatment of Pulmonary Tuberculosis Using Isoniazid and Levofloxacin [Phase 1]
A Phase 1 pilot study evaluating a rapid methodology to assess bactericidal activity, tolerability, and pharmacokinetics of isoniazid and le…
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CLINICAL_TRIALS trial_result · 2008-08-08Clinical Trial Update: Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine Given to PPD-Negative Adults [Phase 1]
Phase 1 update reporting safety and immunogenicity data for a candidate tuberculosis vaccine tested in PPD-negative adults.
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CLINICAL_TRIALS trial_result · 2008-08-07Clinical Trial Update: Safety and Immunogenicity of MVA85A, in Healthy Volunteers in Cape Town [Phase 1]
Phase 1 safety and immunogenicity study of the MVA85A TB vaccine in healthy volunteers in Cape Town, completed.
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CLINICAL_TRIALS research · 2008-08-06Clinical Trial Update: Lipoarabinomannan (LAM) Enzyme-Linked Immunosorbent Assay (ELISA) in Diagnostics of Childhood Tuberculosis (TB)
Clinical trial update on using Lipoarabinomannan ELISA for diagnosing tuberculosis in children. The current status of the trial is not provi…
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CLINICAL_TRIALS trial_result · 2008-06-12Clinical Trial Update: Detection of Latent Tuberculosis in Hemodialysis Patients
This clinical trial update reports the completion and findings of a study evaluating methods to detect latent tuberculosis in patients under…
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CLINICAL_TRIALS trial_result · 2008-06-11Clinical Trial Update: Short Course Intermittent Regimens for the Treatment of HIV-Associated Tuberculosis [Phase 3]
A Phase 3 clinical trial update evaluating short-course intermittent regimens for HIV-associated tuberculosis. The status of the trial is li…