Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2012-09-18Clinical Trial Update: The Usefulness of Interferon-γ Release Assays and Tuberculin Skin Test for Detection of Latent Tuberculosis Infection
This clinical trial update discusses the usefulness of interferon-γ release assays and the tuberculin skin test for detecting latent tubercu…
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CLINICAL_TRIALS research · 2012-09-13Clinical Trial Update: Surveillance and Follow-up for Latent Tuberculosis Infection and Observation of the Effect of Prophylactic Latent Tuberculosis Treatment in Patients With Severe Chronic Kidney Disease or Receiving Long-term Dialysis
This study from National Taiwan University Hospital monitors latent tuberculosis infection and the occurrence of active tuberculosis in pati…
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CLINICAL_TRIALS trial_result · 2012-08-31Clinical Trial Update: Anti-tuberculosis (TB) Drug Levels and Correlation With Drug Induced Hepatotoxicity
Completed clinical trial evaluating anti-tuberculosis drug levels and their correlation with drug-induced hepatotoxicity. The study aimed to…
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CLINICAL_TRIALS trial_result · 2012-08-30Clinical Trial Update: A BCG Challenge Model Study to Assess Anti-mycobacterial Immunity Induced by BCG and a Candidate TB Vaccine, MVA85A [Phase 1]
This completed Phase 1 study evaluated anti-mycobacterial immune responses induced by BCG and the candidate TB vaccine MVA85A using a BCG ch…
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CLINICAL_TRIALS research · 2012-08-29Clinical Trial Update: A Knowledge Translation Intervention for TB/HIV Treatment Adherence, in Zomba District, Malawi [NA]
A completed clinical trial update assessing a knowledge translation intervention to improve tuberculosis treatment adherence (in TB/HIV care…
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CLINICAL_TRIALS trial_result · 2012-08-22Clinical Trial Update: Vitamin D Supplementation Enhances Immune Response to Bacille-Calmette-Guerin (BCG) Vaccination in Infants [NA]
A completed clinical trial suggests vitamin D supplementation may enhance the immune response to Bacille Calmette-Guérin vaccination in infa…
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CLINICAL_TRIALS trial_result · 2012-08-16Clinical Trial Update: Study of AERAS 422 in Healthy Adults [Phase 1]
The Phase 1 study of the TB vaccine candidate AERAS 422 in healthy adults has completed.
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CLINICAL_TRIALS trial_result · 2012-08-15Clinical Trial Update: TMC207-C202: Study to Evaluate Bactericidal Activity of Multiple Oral Doses of TMC207 in Subjects With Sputum-Smear Positive Tuberculosis [Phase 2]
A Phase 2 clinical trial update evaluating bactericidal activity of multiple oral doses of bedaquiline (TMC207) in adults with sputum smear-…
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CLINICAL_TRIALS trial_result · 2012-08-15Clinical Trial Update: TMC207-TiDP13-C110: Interaction Study With Lopinavir/Ritonavir in Healthy Volunteer [Phase 1]
Phase 1 interaction study evaluating bedaquiline (TMC207) with lopinavir/ritonavir in healthy volunteers. The study has completed.
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CLINICAL_TRIALS research · 2012-08-13Clinical Trial Update: EARNEST Rifabutin Pharmacokinetics (PK) Substudy [Phase 2]
An update on the rifabutin pharmacokinetics substudy of the EARNEST trial (Phase 2) in HIV and tuberculosis, with results not yet reported.
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CLINICAL_TRIALS trial_result · 2012-08-03Clinical Trial Update: Safety and Efficacy of Oral Immunomodulator in Tuberculosis (TB) and TB/HIV Patients [Phase 2]
Phase 2 clinical trial assessing the safety and efficacy of an oral immunomodulator in tuberculosis and TB/HIV patients has completed.
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CLINICAL_TRIALS trial_result · 2012-08-03Clinical Trial Update: Role of Vitamin D in Innate Immunity to Tuberculosis [NA]
A completed clinical trial evaluating whether vitamin D supplementation modulates innate immunity in tuberculosis.
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Bioequivalence Study Comparing Rifampicin In A Fixed-Dose Combination (Rifampicin+Isoniazid, Myrin© 2) And The Reference Drug (Rifampicin, Rimactane®) [Phase 1]
A Phase 1 bioequivalence study compared a fixed-dose combination of rifampicin and isoniazid (Myrin 2) with rifampicin alone (Rimactane) to …
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CLINICAL_TRIALS research · 2012-07-24Clinical Trial Update: Rapid Diagnosis of Pulmonary Tuberculosis [NA]
Update on a University of Cape Town trial for rapid diagnosis of pulmonary tuberculosis; current status is unknown.
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CLINICAL_TRIALS trial_result · 2012-07-17Clinical Trial Update: Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected Persons [NA]
Clinical trial update notes the completion of a study evaluating isoniazid plus antiretroviral therapy to prevent tuberculosis in HIV-infect…
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CLINICAL_TRIALS research · 2012-06-11Clinical Trial Update: Reproducibility of Computed Tomography
This completed clinical trial from Universidade Federal do Rio de Janeiro reports on the reproducibility of computed tomography for patients…
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CLINICAL_TRIALS trial_result · 2012-06-11Clinical Trial Update: A Phase 1, Open Label, Placebo-Controlled Study to Evaluate the Effect of GSK1349572 on Iohexol and Para-Aminohippurate Clearance in Healthy Subjects [Phase 1]
Phase 1 trial update describing a Phase 1 open-label, placebo-controlled pharmacokinetic study of GSK1349572 (dolutegravir) assessing its ef…
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CLINICAL_TRIALS trial_result · 2012-06-05Clinical Trial Update: TBTC Study 23C: Pharmacokinetics of Intermittent Rifabutin and Isoniazid With Daily Efavirenz [Phase 2]
This Phase 2 pharmacokinetic study reports on the intermittent rifabutin and isoniazid regimens co-administered with daily efavirenz in indi…
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CLINICAL_TRIALS trial_result · 2012-03-19Clinical Trial Update: Should Low Birth Weight Infants Be Vaccinated With BCG Vaccine at Birth in Developing Countries? [Phase 4]
Phase 4 trial evaluating whether administering the Bacillus Calmette-Guérin (BCG) vaccine at birth to low birth weight infants in developing…
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CLINICAL_TRIALS trial_result · 2012-03-19Clinical Trial Update: Medical and Economical Impact of IGRAs Diagnosis of Latent Tuberculosis in HIV-infected Patients [NA]
This update reports on the medical and economic implications of using Interferon-Gamma Release Assays (IGRAs) to diagnose latent tuberculosi…
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CLINICAL_TRIALS trial_result · 2012-03-16Clinical Trial Update: Early vs Late Introduction of Antiretroviral Therapy in HIV-infected Patients With Tuberculosis (ANRS 1295 CAMELIA) [Phase 3]
Phase 3 trial CAMELIA compared early versus delayed initiation of antiretroviral therapy in HIV-infected patients with tuberculosis; the stu…
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CLINICAL_TRIALS trial_result · 2012-03-16Clinical Trial Update: A Bioequivalence Study Comparing A Fixed Dose Combination Formulation Of Myrin P Forte That Contains Rifampicin, Isoniazid, Ethambutol And Pyrazinamide Per Tablet To An Equivalent Dose Of Single Drug Reference Preparations Of Similar Combination Following Oral Administration In Healthy Adults [Phase 1]
A Phase 1 bioequivalence study comparing a fixed-dose combination of rifampicin, isoniazid, ethambutol and pyrazinamide per tablet to the eq…
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CLINICAL_TRIALS trial_result · 2012-02-16Clinical Trial Update: Study of Safety and Efficacy of Different Regimes of Reintroduction of Anti-TB Drugs in Anti-TB Drugs Induced Liver Damage [Phase 4]
This Phase 4 study evaluates safety and efficacy of different regimens for reintroducing anti-tuberculosis drugs in patients who developed l…
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CLINICAL_TRIALS trial_result · 2012-02-15Clinical Trial Update: Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146 CARINEMO) [Phase 2, Phase 3]
A Phase 2/3 study (ANRS 12146 CARINEMO) comparing nevirapine to efavirenz in HIV-TB co-infected patients has completed Phase 2 and Phase 3.
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CLINICAL_TRIALS trial_result · 2012-02-09Clinical Trial Update: Comparison of Door-to-door Versus Community Gathering to Provide HIV Counseling and Testing Services in Rural Lesotho [NA]
This update reports a completed trial comparing door-to-door versus community gathering approaches for HIV counseling and testing in rural L…